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Spots Global Cancer Trial Database for Ovarian Reserve in Premenopausal Breast Cancer

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Ovarian Reserve in Premenopausal Breast Cancer

Official Title: A Study to Determine Alteration of Hormone Levels in Premenopausal Patients Receiving Adjuvant or Neo-adjuvant Chemotherapy for Breast Cancer

Study ID: NCT01726322

Interventions

Study Description

Brief Summary: This is a translational, mutlicentre study. The aim of this study is to determine whether pre-treatment levels of hormones predict ovarian follicular reserve post adjuvant or neoadjuvant chemotherapy for breast cancer and chemotherapy induced amenorrhea.

Detailed Description: It is proposed that levels of AMH and inhibin A and B measured will give an indication of the residual ovarian reserve in women with breast cancer treated with chemotherapy. In addition, AMH might give an indication of the possible efficacy of GNRH agonists in fertility preservation and the effect on ovarian follicular reserve using different adjuvant chemotherapy regimens. Those likely to be offered GNRH agonists are younger women with no children and a wish to have some in the future. Older women who have completed their families are less likely to be offered a GNRH agonist.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Beacon Hospital, Dublin, Dublin 18, Ireland

Our Lady of Lourdes Hospital, Drogheda, Louth, Ireland

Bon Secours Hospital, Cork, , Ireland

Cork University Hospital, Cork, , Ireland

Beaumont Hospital, Dublin, , Ireland

St James Hospital, Dublin, , Ireland

St Vincent's University Hospital, Dublin, , Ireland

Tallaght University Hospital, Dublin, , Ireland

Sligo General Hospital, Sligo, , Ireland

Waterford Regional Hospital, Waterford, , Ireland

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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