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Brief Title: Intergroup Trial for Children or Adolescents With Primary Mediastinal Large B-Cell Lymphoma: DA-EPOCH-Rituximab Evaluation
Official Title: Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients - Phase II Trial of DA-EPOCH-Rituximab in PMLBL
Study ID: NCT01516567
Brief Summary: Phase II trial to determine the efficacy of Dose Adjusted-EPOCH-Rituximab regimen in children and adolescent with primary mediastinal large B cell lymphoma in terms of event free survival.
Detailed Description:
Minimum Age: 6 Months
Eligible Ages: CHILD
Sex: ALL
Healthy Volunteers: No
University Hospitals Leuven, Leuven, , Belgium
Children Oncology Group Operations centres, Monrovia, , Canada
Gustave Roussy, Villejuif, , France
2nd Dept. of Pediatrics Semmelweis Univ., Budapest, , Hungary
Associazione Italiana di Ematologia ed Oncologia Pediatrica, Padova, , Italy
Emma Children's Hospital, Amsterdam, , Netherlands
Rectorat of Medical University, Wroclaw, , Poland
Sociedad Española de Hematología y Oncología Pediátricas, Valencia, , Spain
University of Birmingham, Birmingham, , United Kingdom
Name: Catherine PATTE, MD
Affiliation: Institut Gustave Roussy, Villejuif, FRANCE
Role: STUDY_CHAIR
Name: Thomas GROSS, MD
Affiliation: Children's Oncology Group, USA
Role: STUDY_CHAIR