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Brief Title: DNA Methylation in Adenocarcinoma of the Prostate: Analysis of Validated Biomarkers in Urine
Official Title: DNA Methylation in Adenocarcinoma of the Prostate: Analysis of Validated Biomarkers in Urine
Study ID: NCT06347809
Brief Summary: This study explores the potential use of DNA markers in the detection of prostate cancer and patient perceptions of this screening approach and other current or future prostate cancer screening and diagnostic tests.
Detailed Description: PRIMARY OBJECTIVE: I. To assess the accuracy of MDM candidates (individually and in combination) assayed from urine and prostatic fluid (collected following digital prostate massage) for detection of CAP. OUTLINE: This is an observational study. PHASE I: Participants undergo urine sample collection on study. PHASE II: Participants undergo standard prostate massage and collection of prostatic fluid and urine samples on study. All participants complete a questionnaire and have their medical records reviewed on study.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: Yes
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Name: John B. Kisiel, M.D.
Affiliation: Mayo Clinic in Rochester
Role: PRINCIPAL_INVESTIGATOR