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Brief Title: Pembrolizumab and Lenvatinib in Advanced/Metastatic Neuroendocrine Prostate Cancer
Official Title: Phase II Trial of Pembrolizumab and Lenvatinib in Advanced/Metastatic Neuroendocrine Prostate Cancer
Study ID: NCT04848337
Brief Summary: Eligible patients will be treated with the combination of lenvatinib and pembrolizumab. A cycle equals 21 days and therapy will continue until radiographic progression, intolerable toxicity, or patient/physician wishes to discontinue protocol therapy. A maximum of 35 cycles may be administered. On Day 1, when both pembrolizumab and lenvatinib are administered, patients should take the lenvatinib per their normal routine.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
City of Hope, Duarte, California, United States
Winship Cancer Instituted of Emory University, Atlanta, Georgia, United States
University of Michigan Health System, Ann Arbor, Michigan, United States
Oregon health, Portland, Oregon, United States
Froedtert and The Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Name: Ulka Vaishampayan, MD
Affiliation: University of Michigan
Role: PRINCIPAL_INVESTIGATOR