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Brief Title: Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer
Official Title: A Phase 1/2, Open-label, Dose Escalation, and Cohort Expansion Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer
Study ID: NCT03888612
Brief Summary: Phase 1/2 dose escalation study to assess the safety and tolerability of ARV-110 in men with mCRPC who have progressed on prior approved systemic therapies for their castrate resistant disease (one of which must be enzalutamide or abiraterone).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Clinical Trial Site, Los Angeles, California, United States
Clinical Trial Site, Orange, California, United States
Clinical Trial Site, San Francisco, California, United States
Clinical Trial Site, New Haven, Connecticut, United States
Clinical Trial Site, Altamonte Springs, Florida, United States
Clinical Trial Site, Bonita Springs, Florida, United States
Clinical Trial Site, Bradenton, Florida, United States
Clinical Trial Site, Brandon, Florida, United States
Clinical Trial Site, Cape Coral, Florida, United States
Clinical Trial Site, Clearwater, Florida, United States
Clinical Trial Site, Daytona Beach, Florida, United States
Clinical Trial Site, Fleming Island, Florida, United States
Clinical Trial Site, Fort Myers, Florida, United States
Clinical Trial Site, Gainesville, Florida, United States
Clinical Trial Site, Largo, Florida, United States
Clinical Trial Site, Lecanto, Florida, United States
Clinical Trial Site, Naples, Florida, United States
Clinical Trial Site, New Port Richey, Florida, United States
Clinical Trial Site, Ocala, Florida, United States
Clinical Trial Site, Orange City, Florida, United States
Clinical Trial Site, Orlando, Florida, United States
Clinical Trial Site, Port Charlotte, Florida, United States
Clinical Trial Site, Saint Petersburg, Florida, United States
Clinical Trial Site, Sarasota, Florida, United States
Clinical Trial Site, Spring Hill, Florida, United States
Clinical Trial Site, Stuart, Florida, United States
Clinical Trial Site, Tampa, Florida, United States
Clinical Trial Site, Tavares, Florida, United States
Clinical Trial Site, The Villages, Florida, United States
Clinical Trial Site, Venice, Florida, United States
Clinical Trial Site, Vero Beach, Florida, United States
Clinical Trial Site, Wellington, Florida, United States
Clinical Trial Site, West Palm Beach, Florida, United States
Clinical Trial Site, Winter Park, Florida, United States
Clinical Trial Site, Chicago, Illinois, United States
Clinical Trial Site, New Orleans, Louisiana, United States
Clinical Trial Site, Boston, Massachusetts, United States
Clinical Trial Site, Detroit, Michigan, United States
Clinical Trial Site, Omaha, Nebraska, United States
Clinical Trial Site, Las Vegas, Nevada, United States
Clinical Trial Site, New York, New York, United States
Clinical Trial Site, Portland, Oregon, United States
Clinical Trial Site, Dickson, Tennessee, United States
Clinical Trial Site, Franklin, Tennessee, United States
Clinical Trial Site, Gallatin, Tennessee, United States
Clinical Trial Site, Hendersonville, Tennessee, United States
Clinical Trial Site, Hermitage, Tennessee, United States
Clinical Trial Site, Lebanon, Tennessee, United States
Clinical Trial Site, Murfreesboro, Tennessee, United States
Clinical Trial Site, Nashville, Tennessee, United States
Clinical Trial Site, Shelbyville, Tennessee, United States
Clinical Trial Site, Smyrna, Tennessee, United States
Clinical Trial Site, Salt Lake City, Utah, United States
Clinical Trial Site, Charlottesville, Virginia, United States