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Brief Title: Ultrahypofractionated, Adaptive Radiation Therapy of Prostate Cancer
Official Title: Ultrahypofractionated, Adaptive Radiation Therapy of Prostate Cancer - Ultra-HART
Study ID: NCT06355050
Brief Summary: In this prospective, multi-center cohort study, the tolerability and quality of life during ultrahypofractionated radiotherapy (RT) of early stage prostate cancer is surveyed at several institutions in Germany. Radiotherapy is delivered with by an online-adaptive RT device (Varian Ethos), which is able to correct daily variations in anatomy and to adjust the irradiation plan accordingly. A digital patient questionnaire is used to asses quality of life longitudinally. Quality of life (QoL) and toxicity profiles will be correlated with planning parameters and compared to retrospective cohorts of patients who underwent normofractionated RT or moderately hypofractionated RT, respectively.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Department of Radiotherapy and Radiation Oncology, Jena University Hospital, Jena, , Germany