Spots Global Cancer Trial Database for Seed Movement in Prostate Brachytherapy Implants: Clinical Measurement and Dosimetric Consequences

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Trial Identification

Brief Title: Seed Movement in Prostate Brachytherapy Implants: Clinical Measurement and Dosimetric Consequences

Official Title: Seed Movement in Prostate Brachytherapy Implants: Clinical Measurement and Dosimetric Consequences

Study ID: NCT01355185

Conditions

Prostate Cancer

Interventions

Study Description

Brief Summary: There are substantial uncertainties with contemporary seed placement techniques in prostate brachytherapy, particularly with the impact of seed movement after an implant due to edema and migration of seeds in the prostate and peri-prostatic tissues. This study will accrue 20 patients undergoing prostate brachytherapy implants and perform serial CT and MRI scans at specified intervals (pre-operatively, day 0, day 3, day 10 and day 28) to characterize these phenomena.

Detailed Description: Prostate brachytherapy is an effective treatment option for men with localized prostate cancer with excellent cure rates and a favorable toxicity profile. Having a more detailed understanding of seed movement after an implant will provide clinicians with details about the clinical impact of these phenomena on implants and provide the detailed understanding of these phenomena that are necessary for more sophisticated brachytherapy implants that are envisioned in the future.