Spots Global Cancer Trial Database for Study of a Polymorphism in Patients With Prostate Cancer

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Study of a Polymorphism in Patients With Prostate Cancer

Official Title: Retrospective Analysis of Endostatin Genotype in Prostate Cancer Patients to Assess the Association of a Single Nucleotide Polymorphism (D104N) in Endostatin and Prostate Cancer

Study ID: NCT00900185

Conditions

Prostate Cancer

Interventions

mutation analysis

polymerase chain reaction

polymorphism analysis

Study Description

Brief Summary: RATIONALE: Studying samples of blood from patients with cancer and from healthy participants in the laboratory may help doctors learn more about changes that may occur in DNA. PURPOSE: This laboratory study is looking at blood samples from patients with prostate cancer and from healthy participants to identify a polymorphism that may help in the study of prostate cancer.

Detailed Description: OBJECTIVES: Primary * Determine the incidence of the D104N COL18A1 polymorphism in patients with prostate cancer. Secondary * Determine the incidence of this polymorphism in African-American patients with prostate cancer. OUTLINE: This is a retrospective, multicenter study. DNA is extracted from preexisting serum samples and polymerase chain reaction is performed to determine the genotype pattern. PROJECTED ACCRUAL: A total of 500 patients and 250 healthy participants will be accrued for this study.