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Brief Title: A Study of Atrasentan in Men With Metastatic, Hormone-Refractory Prostate Cancer
Official Title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of 10 Mg Atrasentan in Men With Metastatic, Hormone-Refractory Prostate Cancer
Study ID: NCT00036543
Brief Summary: This study is being done to evaluate the safety and efficacy of atrasentan in men with metastatic hormone-refractory prostate cancer.
Detailed Description:
Minimum Age: 19 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Urology Centers Of Alabama, Homewood,, Alabama, United States
Alaska Clinical Research Center, LLC, Anchorage, Alaska, United States
Advanced Clinical Trials, Tucson, Arizona, United States
Arkansas Urologial Associates, PA, Little Rock, Arkansas, United States
Robin V. Smith, MD, Chula Vista, California, United States
Urology Associate Of Central California, Fresno,, California, United States
South Valley Medical Plaza, Gilroy, California, United States
San Diego Urology Center, La Mesa, California, United States
UCLA School Of Medicine, Los Angeles,, California, United States
UCLA School of Medicine, Los Angeles, California, United States
Hillcrest Urological Medical Group, Inc., San Diego, California, United States
Urology Associates Of San Luis Obispo, San Luis Obispo,, California, United States
Pacific Clinical Research, Santa Monica, California, United States
Western Clinical Research, Inc., Torrance,, California, United States
Urology Associate, Pc, Denver,, Colorado, United States
South Fl Medical Research, Aventura, Florida, United States
Clinical Physiology Associates, Fort Myers, Florida, United States
Advanced Research Institute, New Port Richey, Florida, United States
Urology Treatment Center, Sarasota,, Florida, United States
Southeastern Urological Center, P.A., Tallahassee, Florida, United States
Winship Cancer Institute Emory University, Atlanta,, Georgia, United States
Sandy Springs Urology, Atlanta, Georgia, United States
Atlanta Va Medical Center, Decatur, Georgia, United States
Dreyer Medical Clinic, Aurora, Illinois, United States
Weiss Memorial Hospital, Chicago,, Illinois, United States
Progressive Care, S.C., Chicago, Illinois, United States
Evanston Hospital Kellogg Cancer Center, Evanston, Illinois, United States
Welborn Clinic, Evansville, Indiana, United States
Urologic Associates, Pc, Davenport, Iowa, United States
Iowa Urology, Des Moines, Iowa, United States
Kansas University Medical Center, Kansas City,, Kansas, United States
Ochsner Clinic, Department of Urology, New Orleans, Louisiana, United States
Regional Urology, Shreveport, Louisiana, United States
LSUHSC, Shreveport, Louisiana, United States
Johns Hopkins Oncology Center, Baltimore, Maryland, United States
Mid Atlantic Clinical Research, Rockville, Maryland, United States
Michigan Institute Of Urology, Pc, St. Clair Shores, Michigan, United States
Lakeside Urology, PC, St. Joseph, Michigan, United States
Mayo Clinic, Rochester, Minnesota, United States
The Medical Oncology Group, Gulfport,, Mississippi, United States
St. Joseph Oncology, St. Joseph, Missouri, United States
Washington University, St. Louis, Missouri, United States
Billings Oncology Associates, Billings,, Montana, United States
Nevada Urology Associate, Reno, Nevada, United States
Albany Medical Center South Clinical Campus, Albany, New York, United States
Albert Einstein College of Medicine, Bronx, New York, United States
HemOnCare, PC, Brooklyn, New York, United States
Beth Israel Medical Center, New York, New York, United States
NYU Medical Center, New York, New York, United States
Nyack Hospital, Nyack, New York, United States
Rochester General Hospital, Rochester, New York, United States
St. Vincent's Medical Center - Staten Island, Staten Island,, New York, United States
The University Of North Carolina At Chapel Hill, Chapel Hill, North Carolina, United States
Blumenthal Cancer Center, Charlotte, North Carolina, United States
The Urology Center, Greensboro,, North Carolina, United States
Urologic Specialists Of Oklahoma, Inc., Tulsa,, Oklahoma, United States
Oregon Urology Specialists, Eugene, Oregon, United States
Urologic Associates of Allentown, Allentown, Pennsylvania, United States
Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States
Urological Associates Of Lancaster, Lancaster, Pennsylvania, United States
Albert Einstein Medical Center, Philadelphia, Pennsylvania, United States
University Of Pittsburgh, Pittsburgh, Pennsylvania, United States
Center for Urologic Care, West Reading,, Pennsylvania, United States
Vanderbilt University Medical Center, Nashville,, Tennessee, United States
Urology Associates, Nashville, Tennessee, United States
Dept of Veteran's Affairs North Texas Healthcare System, Dallas, Texas, United States
Ntouch Research Corporation, Dallas, Texas, United States
Uthscsa, San Antonio, Texas, United States
Scott & White Memorial Hospital, Temple,, Texas, United States
Anthony Middleton, M.D., Salt Lake City,, Utah, United States
Western Urological Clinic, Salt Lake City, Utah, United States
University Of Vermont, Burlington,, Vermont, United States
Virginia Urology Center, Richmond,, Virginia, United States
Jeffrey Frankel, M.D., Seattle,, Washington, United States
Seattle Urological Associates, Seattle, Washington, United States
University Of Washington School Of Medicine, Seattle, Washington, United States
Madigan Army Medical Center, Tacoma,, Washington, United States
Midwest Research Specialists, LLC, Milwaukee, Wisconsin, United States
Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Wyoming Research Foundation, Cheyenne, Wyoming, United States
St Vincent's Clinic, Darlinghurst, New South Wales, Australia
Prince Of Wales Hospital, Randwick, New South Wales, Australia
Westmead Public Hospital, Westmead, New South Wales, Australia
Royal Brisbane Hospital, Herston, Queensland, Australia
Repatriation General Hospital, Daws Park, South Australia, Australia
Peter Maccallum Cancer Institute, East Melbourne, Victoria, Australia
Bayside Urology, Mentone, Victoria, Australia
Royal Melbourne Hospital, Parkville, Victoria, Australia
Hollywood Specialist Centre, Nedlands, Western Australia, Australia
Princess Alexandra Hospital, Woolloongabba, , Australia
Universitatsklinik Innsbruck, Innsbruck, , Austria
Urologische Abteilung, Linz, , Austria
Landesklinik fur Urologie und Andrologie, Salzburg, , Austria
A.Z. Middelheim, Antwerpen, , Belgium
AZ Middelheim, Antwerpen, , Belgium
A Z St Jan, Brugge, , Belgium
University Hospital Erasme, Bruxelles, , Belgium
Uz Gent, Gent, , Belgium
Virga Jesse Hospital, Hasselt, , Belgium
C.H.U. Liege, Liege, , Belgium
St-Elisabeth Ziekenhuis, Turnhout, , Belgium
Tom Baker Cancer Center, Calgary,, Alberta, Canada
Cross Cancer Institute, Edmonton,, Alberta, Canada
Wilson Urology, Kelowna, British Columbia, Canada
Dr. Cal Andreou, Surrey, British Columbia, Canada
Vancouver Hospital & Health Sciences Centre, Vancouver, British Columbia, Canada
Dr. P. J. Pommerville, Inc., Victoria, British Columbia, Canada
Dr. Gary Steinhoff, Clinical Research, Victoria, British Columbia, Canada
Abbott Clinic, Winnipeg, Manitoba, Canada
Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia, Canada
Valley Professional Centre, Kentville, Nova Scotia, Canada
The Male Health Centres, Barrie, Ontario, Canada
Burlington Professional Centre, Burlington, Ontario, Canada
The Urology Resource Centre, Burlington, Ontario, Canada
Kingston General Hospital, Kingston, Ontario, Canada
Probidity Medical Research, Kitchener, Ontario, Canada
London Health Sciences Centre, London, Ontario, Canada
Quest Clinical Trials, Markham, Ontario, Canada
Walk-In Clinic, North Bay, Ontario, Canada
Jack Barkin, M.D., North York, Ontario, Canada
The Male Health Centres, Oakville, Ontario, Canada
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Service Radio-Oncologie, Chus, Fleurimont,, Quebec, Canada
Hopital Notre-Dame, Montreal, Quebec, Canada
Royal Victoria Hospital, Montreal, Quebec, Canada
Ultramed, Pointe Claire, Quebec, Canada
Chuq Pavillon Hotel-Dieu, Quebec, , Canada
Hopital De Pontchaillou, Rennes, Cedex, France
Hopital De Rangueil, Toulouse, Cedex, France
CHU HĂ´pital CĂ´te De Nacre, Caen, , France
HĂ´pital Henri Mondor, Creteil, , France
CHU de BicĂŞtre, Kremlin Bicetre, , France
Hopital Bichat Claude Bernard, Paris, , France
HĂ´pital Foch, Suresnes, , France
Krankenhaus Am Urban, Berlin, , Germany
Allgemeines Krankenhaus Urologie, Celle, , Germany
Universitätsklinikum Carl Gustav Carus an der, Dresden, , Germany
Universitätsklinikum Urologie, Essen, , Germany
Universitätsklinkum, Freiburg, , Germany
Allgemeines Krankenhaus Barmbek, Hamburg, , Germany
Klinik Und Poliklinik fĂźr Urologie und Kinder, Homburg / Saar, , Germany
Universitutsklinikum Lubeck Urologie, LuBECK, , Germany
Universitätsklinikum Mannheim, Mannheim, , Germany
Urologische Klinik Und Poliklinik Grosshadern, Munchen, , Germany
Klinikum Rechts Der Isar, Munchen, , Germany
Universitätsklinikum, Munster, , Germany
Städtische Kliniken, Urologie, Offenbach, , Germany
Universitat Ulm, ULM, , Germany
Klinikum Wuppertal GmbH, Wuppertal, , Germany
'Alexandra' Hospital, Athens, , Greece
Pe.Pa.G.N.I Hospital, Heraklion, , Greece
G. Genimatas Hospital, Thessaloniki, , Greece
Tallaght Hospital, Dublin, , Ireland
St Vincent'S Hospital, Dublin, , Ireland
Mater Misericordiae Hospital, Dublin, , Ireland
Clinica Urologica I - UniversitĂ di Bari, Bari, , Italy
Istituto Nazionale per la Ricerca sul Cancro -IST, Genoa, , Italy
Istituto Europeo di Oncologia, Milan, , Italy
Clinica Urologica - UniversitĂ Di Milano, Milan, , Italy
Istituto di Urologia, Padova, , Italy
Policlinico G. B. Rossi, Verona, , Italy
Amc, Amsterdam, , Netherlands
Rijnstate Hospital, Arnhem, , Netherlands
Medisch Spectrun Twente, Enschede, , Netherlands
Atrium Heerlen, Heerlen, , Netherlands
University Hospital Maastricht, Maastricht, , Netherlands
University Hospital Rotterdam, Rotterdam, , Netherlands
St Franciscus Gasthuis, Rotterdam, , Netherlands
University Hospital Utrecht, Utrecht, , Netherlands
Canterbury Urology Research Trust, Christchurch, , New Zealand
Promed Urology Ltd., Tauranga, , New Zealand
Katedra I Klinika Urologi AM, Gdansk, , Poland
Katedra i Klinika Urologii - Akademia Medyczna w Gdansku, Gdansk, , Poland
Samodzielny Publiczny Zaklad Opieki, Katowice, , Poland
Szpital Kliniczny Dzieciatka Jezus, Warszawa, , Poland
Akademia Medyczna we Wroclawiu, Wroclaw, , Poland
Mediclinic Hospital, Petermaritzburg, 3201, South Africa
Constantiaberg Medi-Clinic, Cape Town, , South Africa
University Of Stellenbosch, Cape Town, , South Africa
University Of Natal - Nelson R Mandela School of Medicine, Durban, , South Africa
Kenridge St Joseph Wingl, Parktown, , South Africa
Medi-Clinic Hospital, Pietermaritzburg, , South Africa
Medical Centre, Pietermaritzburg, , South Africa
Pretoria Urology Hospital, Pretoria, , South Africa
Pretoria Academic Hospital, Pretoria, , South Africa
Fundacion Puigvert, Barcelona, , Spain
Hospital Vall D'Hebron, Barcelona, , Spain
Hospital de Galdakao, Galdakao-Vizcaya, , Spain
Hospital Juan Canalejo, La Coruna, , Spain
Hospital Gregorio Maranon, Madrid, , Spain
Clinica Puerta De Hierro, Madrid, , Spain
Hospital 12 De Octubre, Madrid, , Spain
Hospital Carlos Haya, Malaga, , Spain
Hospital Marques De Valdecilla, Santander, , Spain
Instituto Valenciano De Oncologia, Valencia, , Spain
Sahlgrenska University Hospital, Gothenburg, , Sweden
Helsingborg Hospital, Helsingborg, , Sweden
Linkoping University Hospital, Linkoping, , Sweden
Lund University Hospital, Lund, , Sweden
Malmo University Hospital MAS, Malmo, , Sweden
Orebro Regional Hospital, Orebro, , Sweden
Karolinska Hospital, Stockholm, , Sweden
Umea University Hospital, Umea, , Sweden
Uppsala University Hospital, Uppsala, , Sweden
Zentrum fur Onkologie, Hämatologie und, Aarau, , Switzerland
Inselspital, Universität Bern, Bern, , Switzerland
Chefarzt Urologische Klinik - Universitätsspital Zßrich, Zßrich, , Switzerland
Royal Devon And Exeter Hospital, Exeter,, Devon, United Kingdom
Lister Hospital, Stevenage, Hertfordshire, United Kingdom
Northwick Park Hospital, Harrow, Middlesex, United Kingdom
Western General Hospital, Edinburgh,, Scotland, United Kingdom
Taunton And Somerset Hospital, Taunton, Somerset, United Kingdom
The Institute Of Cancer Research - Royal Marsden Hospital, Sutton, Surrey, United Kingdom
St Lukes Hospital, Bradford, West Yorkshire, United Kingdom
Clatterbridge Centre For Oncology, Bebington, Wirral, United Kingdom
Aberdeen Royal Infirmary, Aberdeen, , United Kingdom
Institute Of Cancer Studies - University of Birmingham, Birmingham, , United Kingdom
Royal Sussex County Hospital, Brighton, , United Kingdom
Southmead Hospital, Bristol, , United Kingdom
Addenbrookes Hospital, Cambridge, , United Kingdom
St Richard'S Hospital, Chichester, , United Kingdom
Leighton Hospital, Crewe, , United Kingdom
Gartnavel General Hospital, Glasgow, , United Kingdom
Glasgow Royal Infirmary, Glasgow, , United Kingdom
Freeman Hospital, High Heaton, , United Kingdom
St Batholomew'S Hospital, London, , United Kingdom
Royal Free Hospital, London, , United Kingdom
Clinical Research Centre - St Georges Hospital, London, , United Kingdom
Nottingham City Hospital, Nottingham, , United Kingdom
Derriford Hospital, Plymouth, , United Kingdom
Hope Hospital, Salford, , United Kingdom
Royal Hallamshire Hospital, Sheffield, , United Kingdom
Southampton General, Southampton, , United Kingdom
Name: Darryl Sleep, M.D.
Affiliation: Abbott
Role: STUDY_DIRECTOR