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Brief Title: Ibrutinib as Neoadjuvant Therapy in Localized Prostate Cancer
Official Title: A Phase 2 Study of Ibrutinib as Neoadjuvant Therapy in Patients With Localized Prostate Cancer
Study ID: NCT02643667
Brief Summary: 30-40% of patients who undergo radical prostatetecomy (RP) with curative intent for their localized prostate cancer experience relapse of their disease. Thus, improved therapeutic approaches are needed in this patient population. Enhancing the patient's anti-tumor immune response prior to surgery may improve long-term outcomes following RP
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
University of California, San Francisco, San Francisco, California, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Name: Russell K Pachynski, M.D.
Affiliation: Washington University School of Medicine
Role: PRINCIPAL_INVESTIGATOR