Spots Global Cancer Trial Database for Early Assessment of Treatment Response Using Functional Diffusion Mapping

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Trial Identification

Brief Title: Early Assessment of Treatment Response Using Functional Diffusion Mapping

Official Title: Early Assessment of Treatment Response Using Functional Diffusion Mapping

Study ID: NCT02064283

Conditions

Prostate Cancer

Interventions

Diffusion MRI

Study Description

Brief Summary: This study will evaluate the feasibility of identifying changes in diffusion MRI characteristics of bone that correlates with response to therapy in men with metastatic prostate cancer.

Detailed Description: This study will evaluate a special type of MRI (magnetic resonance imaging) scan that measures the movement of water molecules through tissue called diffusion MRI. Researchers are using this new MRI technology to track the diffusion, or movement, of water through tumor tissue, and map these changes as a cancer patient undergoes treatment. Early research seems to indicate that tumor cells restrict the movement of water, so as tumor cells die, the movement of water changes within the tumor. These changes in the movement (diffusion) of water may help doctors determine earlier than traditional tests whether a patient's cancer is responding (getting better) to treatment. This study will evaluate the feasibility of identifying changes in diffusion MRI characteristics of bone that correlates with response to therapy in men with metastatic prostate cancer.