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Brief Title: Radiosensitizing and Radioprotectve Effects of Curcumin in Prostate Cancer
Official Title: Radiation Therapy With or Without Curcumin Supplement in Treating Patients With Prostate Cancer
Study ID: NCT01917890
Brief Summary: Prostate cancer is the second most incident cancer among male population worldwide. Radiation therapy by itself or along with surgery and chemotherapy are the main treatments for prostate cancer however prostate cancer cells are only modestly responsive or even unresponsive to the cytotoxic effects of radiotherapy. Recently some in vitro and in vivo studies showed radiosensitizing and radioprotective effects for curcumin. No clinical trial has been done in this area and it is not yet known whether radiation therapy is more effective with or without curcumin supplements in treating patients with prostate cancer.
Detailed Description:
Minimum Age: 50 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Oncology and radiotherapy department, Besat Hospital, Tehran, , Iran, Islamic Republic of
Name: Reza Rastmanesh, PhD
Affiliation: Clinical Nutrition & Dietetics Dept., Shahid Beheshti University of Medical Sciences,
Role: STUDY_CHAIR