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Brief Title: Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer
Official Title: A Phase III Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer
Study ID: NCT03819101
Brief Summary: This is a 2x2 factorial randomized, multicenter, international, open phase III trial. The primary objective is to evaluate the benefit of acetylsalicylic acid and atorvastatin on overall survival (OS) (main endpoint) for patients with castrate-resistant prostate cancer starting first line treatment for CRPC
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Gustave Roussy Cancer Campus Grand Paris, Villejuif, Val De Marne, France
CHU Besançon Hopital Jean Minjoz, Besançon, , France
Centre Jean Perrin, Clermont-Ferrand, , France
Hôpital Privé Sainte Marguerite, Hyères, , France
Centre Azuréen de Cancérologie, Mougins, , France
Centre Antoine Lacassagne, Nice, , France
Hôpital de la Croix Saint Simon, Paris, , France
Institut Jean Godinot, Reims, , France
Hôpital d'Instruction des Armées Bégin, Saint-Mandé, , France
Institut de Cancérologie Lucien Neuwirth, Saint-Priest-en-Jarez, , France
Hôpital Foch, Suresnes, , France
Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, , France
Klinik Hirslanden Aarau, Aarau, , Switzerland
Kantonsspital Baden, Baden, , Switzerland
Bellinzona Istituto Oncologico, Bellinzona, , Switzerland
Kantonsspital Baselland, Bruderholz, , Switzerland
Kantansspital Graubündern, Chur, , Switzerland
Kantonsspital Münsterlingen, Münsterlingen, , Switzerland
Kantonsspital St.Gallen, Saint Gallen, , Switzerland
Stadtspital Triemli, Zürich, , Switzerland