Spots Global Cancer Trial Database for Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer
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Trial Identification
Brief Title: Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer
Official Title: A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy for Patients With Intermediate-Risk Prostate Cancer
Study ID: NCT00936390
Conditions
Study Description
Brief Summary: RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells and shrink tumors. Androgens can cause the growth of prostate cancer cells. Androgen-deprivation therapy may lessen the amount of androgens made by the body. It is not yet known whether radiation therapy is more effective with or without androgen-deprivation therapy in treating patients with prostate cancer. PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared with radiation therapy given together with androgen-deprivation therapy in treating patients with prostate cancer.
Detailed Description: OBJECTIVES: Primary * Demonstrate an overall survival (OS) advantage in patients with intermediate-risk prostate cancer treated with dose-escalated radiotherapy (RT) with versus without short-term androgen-deprivation therapy (ADT). Secondary * Determine whether the addition of ADT to dose-escalated RT versus RT alone improves clinical failures, biochemical failure by the "nadir +2", freedom from failure, rate of salvage ADT, and prostate cancer-specific mortality in these patients. * Estimate the magnitude of benefit of ADT with respect to OS in patients treated with different RT modalities (i.e., external-beam radiation therapy alone vs low-dose rate brachytherapy boost vs high-dose rate brachytherapy boost). * Compare acute and late treatment adverse events of these regimens and correlate these events with the presence or absence of pre-existing comorbidity as documented by the Adult Comorbidity Evaluation 27 assessment. OUTLINE: This is a multicenter, dose-escalation study of radiotherapy. Patients are stratified according to number of risk factors (1 vs 2-3), comorbidity (ACE-27 grade ≥ 2 vs \< 2), and radiotherapy (RT) modality (dose-escalated external-beam RT \[EBRT\] vs EBRT and low-dose rate brachytherapy boost vs EBRT and high-dose rate brachytherapy boost). Patients are randomized to 1 of 2 treatment arms. After completion of study therapy, patients are followed up periodically.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Locations
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
Fairbanks Memorial Hospital, Fairbanks, Alaska, United States
Arizona Center for Cancer Care-Peoria, Peoria, Arizona, United States
Saint Joseph's Hospital and Medical Center, Phoenix, Arizona, United States
21st Century Oncology-Scottsdale, Scottsdale, Arizona, United States
Mayo Clinic in Arizona, Scottsdale, Arizona, United States
Arizona Oncology Services Foundation, Scottsdale, Arizona, United States
Arizona Oncology Associates-West Orange Grove, Tucson, Arizona, United States
Mercy Cancer Center-Hot Springs, Hot Springs, Arkansas, United States
Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn, California, United States
Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, United States
Sutter Cancer Centers Radiation Oncology Services-Cameron Park, Cameron Park, California, United States
Mercy San Juan Medical Center, Carmichael, California, United States
Enloe Medical Center, Chico, California, United States
21st Century Oncology - El Segundo, El Segundo, California, United States
Fresno Cancer Center, Fresno, California, United States
Saint Agnes Medical Center, Fresno, California, United States
Marin General Hospital, Greenbrae, California, United States
Veterans Administration Long Beach Medical Center, Long Beach, California, United States
Los Angeles County-USC Medical Center, Los Angeles, California, United States
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
Memorial Medical Center, Modesto, California, United States
Kaiser Permanente Oakland-Broadway, Oakland, California, United States
Kaiser Permanente-Oakland, Oakland, California, United States
Desert Regional Medical Center, Palm Springs, California, United States
Stanford Cancer Institute, Palo Alto, California, United States
Feather River Cancer Center, Paradise, California, United States
Pomona Valley Hospital Medical Center, Pomona, California, United States
Kaiser Permanente-Rancho Cordova Cancer Center, Rancho Cordova, California, United States
Kaiser Permanente-Redwood City, Redwood City, California, United States
Kaiser Permanente-Richmond, Richmond, California, United States
Rohnert Park Cancer Center, Rohnert Park, California, United States
Kaiser Permanente-Roseville, Roseville, California, United States
Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California, United States
The Permanente Medical Group-Roseville Radiation Oncology, Roseville, California, United States
Sutter General Hospital, Sacramento, California, United States
University of California Davis Comprehensive Cancer Center, Sacramento, California, United States
Mercy General Hospital Radiation Oncology Center, Sacramento, California, United States
Kaiser Permanente-South Sacramento, Sacramento, California, United States
South Sacramento Cancer Center, Sacramento, California, United States
Kaiser Permanente - Sacramento, Sacramento, California, United States
University of California San Diego, San Diego, California, United States
Kaiser Permanente-San Francisco, San Francisco, California, United States
UCSF Medical Center-Mount Zion, San Francisco, California, United States
California Pacific Medical Center-Pacific Campus, San Francisco, California, United States
Kaiser Permanente-Santa Teresa-San Jose, San Jose, California, United States
Kaiser Permanente San Leandro, San Leandro, California, United States
Kaiser Permanente-San Rafael, San Rafael, California, United States
Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California, United States
Kaiser Permanente-Santa Rosa, Santa Rosa, California, United States
Kaiser Permanente Cancer Treatment Center, South San Francisco, California, United States
Kaiser Permanente-South San Francisco, South San Francisco, California, United States
Kaiser Permanente-Stockton, Stockton, California, United States
David Grant United States Air Force Medical Center, Travis Air Force Base, California, United States
Tahoe Forest Cancer Center, Truckee, California, United States
Sutter Cancer Centers Radiation Oncology Services-Vacaville, Vacaville, California, United States
Sutter Solano Medical Center/Cancer Center, Vallejo, California, United States
Kaiser Permanente-Walnut Creek, Walnut Creek, California, United States
Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado, United States
University of Colorado Cancer Center - Anschutz Cancer Pavilion, Aurora, Colorado, United States
The Urology Center of Colorado, Denver, Colorado, United States
The Shaw Regional Cancer Center, Edwards, Colorado, United States
Poudre Valley Hospital, Fort Collins, Colorado, United States
Saint Mary's Hospital and Regional Medical Center, Grand Junction, Colorado, United States
Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado, United States
Hartford Hospital, Hartford, Connecticut, United States
Saint Francis Hospital and Medical Center, Hartford, Connecticut, United States
Midstate Medical Center, Meriden, Connecticut, United States
The Hospital of Central Connecticut, New Britain, Connecticut, United States
Yale-New Haven Hospital Saint Raphael Campus, New Haven, Connecticut, United States
Helen F Graham Cancer Center, Newark, Delaware, United States
Christiana Care Health System-Christiana Hospital, Newark, Delaware, United States
University of Miami Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida, United States
Broward Health Medical Center, Fort Lauderdale, Florida, United States
Mayo Clinic in Florida, Jacksonville, Florida, United States
Florida Hospital Kissimmee, Kissimmee, Florida, United States
Lakeland Regional Cancer Center, Lakeland, Florida, United States
The Watson Clinic, Lakeland, Florida, United States
Jackson Memorial Hospital-Holtz Children's Hospital, Miami, Florida, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida, United States
South Miami Hospital, Miami, Florida, United States
Florida Hospital Orlando, Orlando, Florida, United States
Bay Medical Center, Panama City, Florida, United States
James A. Haley Veterans Affairs Hospital, Tampa, Florida, United States
Grady Health System, Atlanta, Georgia, United States
Piedmont Hospital, Atlanta, Georgia, United States
Emory University/Winship Cancer Institute, Atlanta, Georgia, United States
Northside Hospital, Atlanta, Georgia, United States
John B Amos Cancer Center, Columbus, Georgia, United States
Northside Hospital-Forsyth, Cumming, Georgia, United States
Atlanta VA Medical Center, Decatur, Georgia, United States
Piedmont Fayette Hospital, Fayetteville, Georgia, United States
Northeast Georgia Medical Center, Gainesville, Georgia, United States
Memorial University Medical Center, Savannah, Georgia, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia, United States
Queen's Medical Center, Honolulu, Hawaii, United States
University of Hawaii Cancer Center, Honolulu, Hawaii, United States
The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii, United States
Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho, United States
Idaho Urologic Institute-Meridian, Meridian, Idaho, United States
Kootenai Cancer Center, Post Falls, Idaho, United States
Saint Anthony's Health, Alton, Illinois, United States
Memorial Hospital of Carbondale, Carbondale, Illinois, United States
Northwestern University, Chicago, Illinois, United States
John H Stroger Jr Hospital of Cook County, Chicago, Illinois, United States
University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States
Advocate Illinois Masonic Medical Center, Chicago, Illinois, United States
Decatur Memorial Hospital, Decatur, Illinois, United States
Crossroads Cancer Center, Effingham, Illinois, United States
Hines Veterans Administration Hospital, Hines, Illinois, United States
Loyola University Medical Center, Maywood, Illinois, United States
Pekin Cancer Treatment Center, Pekin, Illinois, United States
OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC, Peoria, Illinois, United States
OSF Saint Francis Medical Center, Peoria, Illinois, United States
SwedishAmerican Regional Cancer Center/ACT, Rockford, Illinois, United States
Saint John's Hospital, Springfield, Illinois, United States
Memorial Medical Center, Springfield, Illinois, United States
Memorial and Saint Elizabeth's Health Care Services LLP, Swansea, Illinois, United States
Saint Vincent Anderson Regional Hospital/Cancer Center, Anderson, Indiana, United States
IU Health West Hospital, Avon, Indiana, United States
IU Health Bloomington, Bloomington, Indiana, United States
Radiation Oncology Associates PC, Fort Wayne, Indiana, United States
Parkview Hospital Randallia, Fort Wayne, Indiana, United States
IU Health Goshen Center for Cancer Care, Goshen, Indiana, United States
Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States
IU Health Methodist Hospital, Indianapolis, Indiana, United States
Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana, United States
IU Health Central Indiana Cancer Centers-East, Indianapolis, Indiana, United States
McFarland Clinic PC-William R Bliss Cancer Center, Ames, Iowa, United States
Medical Oncology and Hematology Associates-West Des Moines, Clive, Iowa, United States
Iowa Methodist Medical Center, Des Moines, Iowa, United States
Iowa Oncology Research Association CCOP, Des Moines, Iowa, United States
Medical Oncology and Hematology Associates-Des Moines, Des Moines, Iowa, United States
Medical Oncology and Hematology Associates-Laurel, Des Moines, Iowa, United States
Mercy Medical Center - Des Moines, Des Moines, Iowa, United States
Iowa Lutheran Hospital, Des Moines, Iowa, United States
Finley Hospital, Dubuque, Iowa, United States
Cancer Center of Kansas - Dodge City, Dodge City, Kansas, United States
Cancer Center of Kansas - El Dorado, El Dorado, Kansas, United States
Lawrence Memorial Hospital, Lawrence, Kansas, United States
Kansas City Cancer Centers-Southwest, Overland Park, Kansas, United States
Cancer Center of Kansas - Wellington, Wellington, Kansas, United States
Associates In Womens Health, Wichita, Kansas, United States
Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas, United States
Cancer Center of Kansas - Main Office, Wichita, Kansas, United States
Via Christi Regional Medical Center, Wichita, Kansas, United States
Wesley Medical Center, Wichita, Kansas, United States
Wichita CCOP, Wichita, Kansas, United States
Cancer Center of Kansas - Winfield, Winfield, Kansas, United States
Baptist Health Lexington, Lexington, Kentucky, United States
University of Kentucky/Markey Cancer Center, Lexington, Kentucky, United States
The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky, United States
Owensboro Health Mitchell Memorial Cancer Center, Owensboro, Kentucky, United States
Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, United States
Tulane University Health Sciences Center, New Orleans, Louisiana, United States
Ochsner Medical Center Jefferson, New Orleans, Louisiana, United States
Central Maine Medical Center, Lewiston, Maine, United States
Maine Medical Center- Scarborough Campus, Scarborough, Maine, United States
Anne Arundel Medical Center, Annapolis, Maryland, United States
University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland, United States
Greater Baltimore Medical Center, Baltimore, Maryland, United States
Saint Agnes Hospital, Baltimore, Maryland, United States
Upper Chesapeake Medical Center, Bel Air, Maryland, United States
Walter Reed National Military Medical Center, Bethesda, Maryland, United States
Central Maryland Radiation Oncology in Howard County, Columbia, Maryland, United States
Tate Cancer Center, Glen Burnie, Maryland, United States
Holy Cross Hospital, Silver Spring, Maryland, United States
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States
Boston Medical Center, Boston, Massachusetts, United States
Mass General/North Shore Cancer Center, Danvers, Massachusetts, United States
Saint Anne's Hospital, Fall River, Massachusetts, United States
Cape Cod Hospital, Hyannis, Massachusetts, United States
Lowell General Hospital, Lowell, Massachusetts, United States
Berkshire Hematology Oncology PC, Pittsfield, Massachusetts, United States
Beth Israel Deaconess Hospital-Plymouth, Plymouth, Massachusetts, United States
D'Amour Center for Cancer Care, Springfield, Massachusetts, United States
Baystate Medical Center, Springfield, Massachusetts, United States
Saint Vincent Hospital/Reliant Medical Group, Worcester, Massachusetts, United States
Bixby Medical Center, Adrian, Michigan, United States
Veteran's Administration Medical Center - Ann Arbor, Ann Arbor, Michigan, United States
Saint Joseph Mercy Hospital, Ann Arbor, Michigan, United States
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States
Bronson Battle Creek, Battle Creek, Michigan, United States
McLaren-Bay Region, Bay City, Michigan, United States
Henry Ford Macomb Hospital, Clinton Township, Michigan, United States
Huron Valley-Sinai Hospital, Commerce, Michigan, United States
Henry Ford Hospital, Detroit, Michigan, United States
Saint John Hospital and Medical Center, Detroit, Michigan, United States
Green Bay Oncology - Escanaba, Escanaba, Michigan, United States
21st Century Oncology-Farmington Hills, Farmington Hills, Michigan, United States
Botsford General Hospital, Farmington, Michigan, United States
Genesys Hurley Cancer Institute, Flint, Michigan, United States
Genesys Regional Medical Center-West Flint Campus, Flint, Michigan, United States
McLaren-Flint, Flint, Michigan, United States
Mercy Health Saint Mary's, Grand Rapids, Michigan, United States
Spectrum Health at Butterworth Campus, Grand Rapids, Michigan, United States
Green Bay Oncology - Iron Mountain, Iron Mountain, Michigan, United States
Borgess Medical Center, Kalamazoo, Michigan, United States
Bronson Methodist Hospital, Kalamazoo, Michigan, United States
West Michigan Cancer Center, Kalamazoo, Michigan, United States
Sparrow Hospital, Lansing, Michigan, United States
Great Lakes Cancer Institute-Lapeer Campus, Lapeer, Michigan, United States
McLaren-Macomb, Mount Clemens, Michigan, United States
McLaren-Central Michigan, Mount Pleasant, Michigan, United States
Mercy Health Mercy Campus, Muskegon, Michigan, United States
McLaren Cancer Institute-Owosso, Owosso, Michigan, United States
Northern Michigan Regional Hospital, Petoskey, Michigan, United States
Saint Joseph Mercy Oakland, Pontiac, Michigan, United States
Saint Joseph Mercy Port Huron, Port Huron, Michigan, United States
Crittenton Hospital, Rochester, Michigan, United States
William Beaumont Hospital-Royal Oak, Royal Oak, Michigan, United States
Saint Mary's of Michigan, Saginaw, Michigan, United States
Downriver Center for Oncology, Trenton, Michigan, United States
21st Century Oncology-Troy, Troy, Michigan, United States
William Beaumont Hospital - Troy, Troy, Michigan, United States
Saint John Macomb-Oakland Hospital, Warren, Michigan, United States
Henry Ford West Bloomfield Hospital, West Bloomfield, Michigan, United States
Mayo Clinic Health System in Albert Lea, Albert Lea, Minnesota, United States
Sanford Clinic North-Bemidgi, Bemidji, Minnesota, United States
Miller-Dwan Hospital, Duluth, Minnesota, United States
Saint Luke's Hospital of Duluth, Duluth, Minnesota, United States
Fairview-Southdale Hospital, Edina, Minnesota, United States
Mayo Clinic Health Systems-Mankato, Mankato, Minnesota, United States
Mayo Clinic, Rochester, Minnesota, United States
Regions Hospital, Saint Paul, Minnesota, United States
Saint Francis Medical Center, Cape Girardeau, Missouri, United States
Mercy Hospital-Joplin, Joplin, Missouri, United States
Kansas City Cancer Center - South, Kansas City, Missouri, United States
Kansas City Cancer Centers - North, Kansas City, Missouri, United States
Kansas City Cancer Center-Lee's Summit, Lee's Summit, Missouri, United States
Phelps County Regional Medical Center, Rolla, Missouri, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Siteman Cancer Center-South County, Saint Louis, Missouri, United States
Missouri Baptist Medical Center, Saint Louis, Missouri, United States
Barnes-Jewish West County Hospital, Saint Louis, Missouri, United States
Mercy Hospital Saint Louis, Saint Louis, Missouri, United States
Saint Louis-Cape Girardeau CCOP, Saint Louis, Missouri, United States
Siteman Cancer Center - Saint Peters, Saint Peters, Missouri, United States
Cancer Research for the Ozarks NCORP, Springfield, Missouri, United States
Mercy Hospital Springfield, Springfield, Missouri, United States
CoxHealth South Hospital, Springfield, Missouri, United States
Montana Cancer Consortium CCOP, Billings, Montana, United States
Northern Rockies Radiation Oncology Center, Billings, Montana, United States
Billings Clinic Cancer Center, Billings, Montana, United States
Berdeaux, Donald MD (UIA Investigator), Great Falls, Montana, United States
Great Falls Clinic, Great Falls, Montana, United States
Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States
Missouri Valley Cancer Consortium, Omaha, Nebraska, United States
Nebraska Methodist Hospital, Omaha, Nebraska, United States
Alegent Health Immanuel Medical Center, Omaha, Nebraska, United States
Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States
Alegent Health Lakeside Hospital, Omaha, Nebraska, United States
Creighton University Medical Center, Omaha, Nebraska, United States
University of Nebraska Medical Center, Omaha, Nebraska, United States
Concord Hospital, Concord, New Hampshire, United States
Exeter Hospital, Exeter, New Hampshire, United States
Cheshire Medical Center-Dartmouth-Hitchcock Keene, Keene, New Hampshire, United States
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States
Elliot Hospital, Manchester, New Hampshire, United States
Ocean Medical Center, Brick, New Jersey, United States
Cooper Hospital University Medical Center, Camden, New Jersey, United States
Veterans Adminstration New Jersey Health Care System, East Orange, New Jersey, United States
CentraState Medical Center, Freehold, New Jersey, United States
Princeton Radiation Oncology Center, Monroe, New Jersey, United States
Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County, Mount Holly, New Jersey, United States
Jersey Shore Medical Center, Neptune, New Jersey, United States
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States
UMDNJ - Robert Wood Johnson University Hospital, New Brunswick, New Jersey, United States
UMDNJ - New Jersey Medical School, Newark, New Jersey, United States
Newark Beth Israel Medical Center, Newark, New Jersey, United States
The Medical Center At Princeton, Princeton, New Jersey, United States
Riverview Medical Center/Booker Cancer Center, Red Bank, New Jersey, United States
Sparta Cancer Treatment Center, Sparta, New Jersey, United States
Community Medical Center, Toms River, New Jersey, United States
MD Anderson Cancer Center at Cooper-Voorhees, Voorhees, New Jersey, United States
Virtua West Jersey Hospital Voorhees, Voorhees, New Jersey, United States
Prostate Cancer Center of New Jersey, West Orange, New Jersey, United States
Lovelace Medical Center-Downtown, Albuquerque, New Mexico, United States
University of New Mexico, Albuquerque, New Mexico, United States
University of New Mexico Cancer Center, Albuquerque, New Mexico, United States
Radiation Oncology Associates, Albuquerque, New Mexico, United States
Memorial Medical Center - Las Cruces, Las Cruces, New Mexico, United States
New York Oncology Hematology PC - Albany, Albany, New York, United States
Saint Peters Hospital-Albany, Albany, New York, United States
Southside Hospital, Bay Shore, New York, United States
Lourdes Hospital, Binghamton, New York, United States
State University of New York Downstate Medical Center, Brooklyn, New York, United States
Veteran Affairs New York Harbor Healthcare System-Brooklyn Campus, Brooklyn, New York, United States
Roswell Park Cancer Institute, Buffalo, New York, United States
Sands Cancer Center, Canandaigua, New York, United States
Mary Imogene Bassett Hospital, Cooperstown, New York, United States
Arnot Ogden Medical Center/Falck Cancer Center, Elmira, New York, United States
North Shore University Hospital, Manhasset, New York, United States
North Shore-LIJ Health System NCORP, Manhasset, New York, United States
Long Island Jewish Medical Center, New Hyde Park, New York, United States
North Shore-LIJ Health System/Center for Advanced Medicine, New Hyde Park, New York, United States
Columbia University Medical Center, New York, New York, United States
Hudson Valley Oncology Associates, Poughkeepsie, New York, United States
Highland Hospital, Rochester, New York, United States
University Radiation Oncology, Rochester, New York, United States
University of Rochester, Rochester, New York, United States
Randolph Hospital, Asheboro, North Carolina, United States
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
Duke University Medical Center, Durham, North Carolina, United States
Cone Health Cancer Center, Greensboro, North Carolina, United States
The Coleman Radiation Center-Carteret General Hospital, Morehead City, North Carolina, United States
CarolinaEast Health System-Medical Center, New Bern, North Carolina, United States
Duke Cancer Institute Macon Pond, Raleigh, North Carolina, United States
Rex Cancer Center, Raleigh, North Carolina, United States
South Atlantic Radiation Oncology, Supply, North Carolina, United States
Coastal Carolina Radiation Oncology, Wilmington, North Carolina, United States
New Hanover Regional Medical Center/Zimmer Cancer Center, Wilmington, North Carolina, United States
Southeast Cancer Consortium-Upstate NCORP, Winston-Salem, North Carolina, United States
Mid Dakota Clinic, Bismarck, North Dakota, United States
Saint Alexius Medical Center, Bismarck, North Dakota, United States
Sanford Bismarck Medical Center, Bismarck, North Dakota, United States
Sanford Clinic North-Fargo, Fargo, North Dakota, United States
Sanford Medical Center-Fargo, Fargo, North Dakota, United States
Trinity Cancer Care Center, Minot, North Dakota, United States
Summa Akron City Hospital/Cooper Cancer Center, Akron, Ohio, United States
Akron General Medical Center, Akron, Ohio, United States
Summa Barberton Hospital, Barberton, Ohio, United States
UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio, United States
Geaugra Hospital, Chardon, Ohio, United States
Adena Regional Medical Center, Chillicothe, Ohio, United States
University of Cincinnati, Cincinnati, Ohio, United States
Case Western Reserve University, Cleveland, Ohio, United States
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio, United States
Cleveland Clinic Foundation, Cleveland, Ohio, United States
Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
Riverside Methodist Hospital, Columbus, Ohio, United States
Columbus CCOP, Columbus, Ohio, United States
Grant Medical Center, Columbus, Ohio, United States
The Mark H Zangmeister Center, Columbus, Ohio, United States
Mount Carmel Health Center West, Columbus, Ohio, United States
Doctors Hospital, Columbus, Ohio, United States
Grady Memorial Hospital, Delaware, Ohio, United States
Mercy Cancer Center-Elyria, Elyria, Ohio, United States
Cleveland Clinic Cancer Center Independence, Independence, Ohio, United States
Marietta Memorial Hospital, Marietta, Ohio, United States
Toledo Clinic Cancer Centers-Maumee, Maumee, Ohio, United States
Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio, United States
Summa Health Center at Lake Medina, Medina, Ohio, United States
Lake University Ireland Cancer Center, Mentor, Ohio, United States
Southwest General Health Center Ireland Cancer Center, Middleburg Heights, Ohio, United States
Licking Memorial Hospital, Newark, Ohio, United States
Saint Charles Hospital, Oregon, Ohio, United States
University Hospitals Parma Medical Center, Parma, Ohio, United States
Southern Ohio Medical Center, Portsmouth, Ohio, United States
Robinson Radiation Oncology, Ravenna, Ohio, United States
Cancer Care Center, Incorporated, Salem, Ohio, United States
Ireland Cancer Center at Firelands Regional Medical Center, Sandusky, Ohio, United States
North Coast Cancer Care, Sandusky, Ohio, United States
Flower Hospital, Sylvania, Ohio, United States
University of Toledo, Toledo, Ohio, United States
Mercy Saint Anne Hospital, Toledo, Ohio, United States
University Pointe, West Chester, Ohio, United States
Saint Ann's Hospital, Westerville, Ohio, United States
UHHS-Westlake Medical Center, Westlake, Ohio, United States
Cancer Treatment Center, Wooster, Ohio, United States
Cleveland Clinic Wooster Specialty Center, Wooster, Ohio, United States
Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio, United States
Genesis HealthCare System, Zanesville, Ohio, United States
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Clackamas Radiation Oncology Center, Clackamas, Oregon, United States
Willamette Valley Cancer Center, Eugene, Oregon, United States
Three Rivers Community Hospital, Grants Pass, Oregon, United States
Legacy Mount Hood Medical Center, Gresham, Oregon, United States
Asante Health System, Medford, Oregon, United States
Providence Medford Medical Center, Medford, Oregon, United States
Rogue Valley Medical Center, Medford, Oregon, United States
Providence Milwaukie Hospital, Milwaukie, Oregon, United States
Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon, United States
Providence Portland Medical Center, Portland, Oregon, United States
Western Oncology Research Consortium, Portland, Oregon, United States
Providence Saint Vincent Medical Center, Portland, Oregon, United States
Legacy Meridian Park Hospital, Tualatin, Oregon, United States
Abington Memorial Hospital, Abington, Pennsylvania, United States
Saint Luke's University Hospital-Bethlehem Campus, Bethlehem, Pennsylvania, United States
Bryn Mawr Hospital, Bryn Mawr, Pennsylvania, United States
Geisinger Medical Center, Danville, Pennsylvania, United States
Mercy Fitzgerald Hospital, Darby, Pennsylvania, United States
Delaware County Memorial Hospital, Drexel Hill, Pennsylvania, United States
Northeast Radiation Oncology Center, Dunmore, Pennsylvania, United States
The Regional Cancer Center, Erie, Pennsylvania, United States
Fox Chase Cancer Center Buckingham, Furlong, Pennsylvania, United States
Adams Cancer Center, Gettysburg, Pennsylvania, United States
Cherry Tree Cancer Center, Hanover, Pennsylvania, United States
Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, United States
Academic Urology Prostate Center, King Of Prussia, Pennsylvania, United States
Saint Mary Medical and Regional Cancer Center, Langhorne, Pennsylvania, United States
Upper Delaware Valley Cancer Center, Milford, Pennsylvania, United States
Paoli Memorial Hospital, Paoli, Pennsylvania, United States
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
Temple University Hospital, Philadelphia, Pennsylvania, United States
Albert Einstein Medical Center, Philadelphia, Pennsylvania, United States
VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, United States
Reading Hospital, West Reading, Pennsylvania, United States
Lankenau Medical Center, Wynnewood, Pennsylvania, United States
Mainline Health CCOP, Wynnewood, Pennsylvania, United States
WellSpan Health-York Hospital, York, Pennsylvania, United States
AnMed Health Hospital, Anderson, South Carolina, United States
Medical University of South Carolina, Charleston, South Carolina, United States
Greenville Health System Cancer Institute-Faris, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Eastside, Greenville, South Carolina, United States
Self Regional Healthcare, Greenwood, South Carolina, United States
Greenville Health System Cancer Institute-Greer, Greer, South Carolina, United States
Gibbs Cancer Center-Pelham, Greer, South Carolina, United States
Carolina Regional Cancer Center, Myrtle Beach, South Carolina, United States
Greenville Health System Cancer Institute-Seneca, Seneca, South Carolina, United States
Spartanburg Medical Center, Spartanburg, South Carolina, United States
Greenville Health System Cancer Institute-Spartanburg, Spartanburg, South Carolina, United States
Rapid City Regional Hospital, Rapid City, South Dakota, United States
Wellmont Holston Valley Hospital and Medical Center, Kingsport, Tennessee, United States
Thompson Cancer Survival Center, Knoxville, Tennessee, United States
Blount Memorial Hospital, Maryville, Tennessee, United States
Texas Oncology-Arlington South, Arlington, Texas, United States
Texas Oncology-Austin Midtown, Austin, Texas, United States
Texas Oncology - Central Austin Cancer Center, Austin, Texas, United States
Texas Oncology - South Austin Cancer Center, Austin, Texas, United States
Texas Oncology Bedford, Bedford, Texas, United States
Texas Cancer Center - Medical City Dallas, Dallas, Texas, United States
Texas Oncology Methodist Charlton Cancer Center, Dallas, Texas, United States
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas, United States
Texas Oncology-Denton South, Denton, Texas, United States
Brooke Army Medical Center, Fort Sam Houston, Texas, United States
The Klabzuba Cancer Center, Fort Worth, Texas, United States
University of Texas Medical Branch, Galveston, Texas, United States
Memorial Hermann Memorial City Medical Center, Houston, Texas, United States
M D Anderson Cancer Center, Houston, Texas, United States
UTMB Cancer Center at Victory Lakes, League City, Texas, United States
Texas Oncology - Lewisville, Lewisville, Texas, United States
Texas Oncology-Longview Cancer Center, Longview, Texas, United States
West Texas Cancer Center, Odessa, Texas, United States
Texas Oncology-Seton Williamson, Round Rock, Texas, United States
Texas Oncology - Round Rock Cancer Center, Round Rock, Texas, United States
Texas Cancer Center-Sherman, Sherman, Texas, United States
Texas Oncology Cancer Center Sugar Land, Sugar Land, Texas, United States
Texas Oncology-Wichita Falls Texoma Cancer Center, Wichita Falls, Texas, United States
Sandra L Maxwell Cancer Center, Cedar City, Utah, United States
Intermountain Medical Center, Murray, Utah, United States
McKay-Dee Hospital Center, Ogden, Utah, United States
Utah Valley Regional Medical Center, Provo, Utah, United States
Dixie Medical Center Regional Cancer Center, Saint George, Utah, United States
Utah Cancer Specialists-Salt Lake City, Salt Lake City, Utah, United States
Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah, United States
LDS Hospital, Salt Lake City, Utah, United States
Southwestern Vermont Medical Center, Bennington, Vermont, United States
Rutland Regional Medical Center, Rutland, Vermont, United States
Norris Cotton Cancer Center-North, Saint Johnsbury, Vermont, United States
Inova Alexandria Hospital, Alexandria, Virginia, United States
Danville Regional Medical Center, Danville, Virginia, United States
Augusta Health Cancer Center, Fishersville, Virginia, United States
Sentara Cancer Institute at Sentara CarePlex Hospital, Hampton, Virginia, United States
Sentara Rockingham Memorial Hospital Hahn Cancer Center, Harrisonburg, Virginia, United States
Sentara Hospitals, Norfolk, Virginia, United States
Southwest VA Regional Cancer Center, Norton, Virginia, United States
Naval Medical Center - Portsmouth, Portsmouth, Virginia, United States
Oncology and Hematology Associates of Southwest Virginia, Roanoke, Virginia, United States
Sentara Virginia Beach General Hospital, Virginia Beach, Virginia, United States
PeaceHealth Saint Joseph Medical Center, Bellingham, Washington, United States
Saint Francis Hospital, Federal Way, Washington, United States
Virginia Mason CCOP, Seattle, Washington, United States
Virginia Mason Medical Center, Seattle, Washington, United States
Cancer Care Northwest - Spokane South, Spokane, Washington, United States
Cancer Care Northwest-North Spokane, Spokane, Washington, United States
PeaceHealth Southwest Medical Center, Vancouver, Washington, United States
Compass Oncology Vancouver, Vancouver, Washington, United States
Legacy Salmon Creek Hospital, Vancouver, Washington, United States
Appleton Medical Center, Appleton, Wisconsin, United States
Green Bay Oncology at Saint Vincent Hospital, Green Bay, Wisconsin, United States
Bellin Memorial Hospital, Green Bay, Wisconsin, United States
Saint Vincent Hospital, Green Bay, Wisconsin, United States
Green Bay Oncology Limited at Saint Mary's Hospital, Green Bay, Wisconsin, United States
Saint Mary's Hospital, Green Bay, Wisconsin, United States
Aurora BayCare Medical Center, Green Bay, Wisconsin, United States
UW Cancer Center Johnson Creek, Johnson Creek, Wisconsin, United States
Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States
Mayo Clinic Health System-Franciscan Healthcare, La Crosse, Wisconsin, United States
Bay Area Medical Center, Marinette, Wisconsin, United States
Vince Lombardi Cancer Clinic-Marinette, Marinette, Wisconsin, United States
Community Memorial Hospital, Menomonee Falls, Wisconsin, United States
Columbia Saint Mary's Hospital - Ozaukee, Mequon, Wisconsin, United States
Columbia Saint Mary's Water Tower Medical Commons, Milwaukee, Wisconsin, United States
Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin, United States
Froedtert and the Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Zablocki Veterans Administration Medical Center, Milwaukee, Wisconsin, United States
Green Bay Oncology - Oconto Falls, Oconto Falls, Wisconsin, United States
Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin, United States
Wheaton Franciscan Cancer Care - All Saints, Racine, Wisconsin, United States
Door County Cancer Center, Sturgeon Bay, Wisconsin, United States
Green Bay Oncology - Sturgeon Bay, Sturgeon Bay, Wisconsin, United States
Aurora Medical Center in Summit, Summit, Wisconsin, United States
Aurora West Allis Medical Center, West Allis, Wisconsin, United States
The Alyce and Elmore Kraemer Cancer Care Center, West Bend, Wisconsin, United States
Riverview Hospital, Wisconsin Rapids, Wisconsin, United States
Welch Cancer Center, Sheridan, Wyoming, United States
Tom Baker Cancer Centre, Calgary, Alberta, Canada
Cross Cancer Institute, Edmonton, Alberta, Canada
BCCA-Cancer Centre for the Southern Interior, Kelowna, British Columbia, Canada
BCCA-Vancouver Island Cancer Centre, Victoria, British Columbia, Canada
Atlantic Health Sciences Corporation-Saint John Regional Hospital, Saint John, New Brunswick, Canada
QEII Health Sciences Centre/Capital District Health Authority, Halifax, Nova Scotia, Canada
Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario, Canada
London Regional Cancer Program, London, Ontario, Canada
Ottawa Health Research Institute-General Division, Ottawa, Ontario, Canada
Irving Greenberg Family Cancer Centre, Ottawa, Ontario, Canada
Thunder Bay Regional Health Science Centre, Thunder Bay, Ontario, Canada
Odette Cancer Centre- Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Hopital Maisonneuve-Rosemont, Montreal, Quebec, Canada
CHUM - Hopital Notre-Dame, Montreal, Quebec, Canada
McGill University Department of Oncology, Montreal, Quebec, Canada
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ), Quebec City, Quebec, Canada
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec, Canada
Allan Blair Cancer Centre, Regina, Saskatchewan, Canada
Saskatoon Cancer Centre, Saskatoon, Saskatchewan, Canada
Contact Details
Name: Alvaro A. Martinez, MD, FACR
Affiliation: 21st Century Oncology - Michigan Institute for Radiation Oncology
Role: STUDY_CHAIR
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