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Brief Title: Choline-PET for Evaluating the Incidence of Nodal Metastases Among Newly Diagnosed Patients of Prostate Cancer
Official Title: Evaluation of the Incidence of Choline-PET Detected Nodal Metastases Among Newly Diagnosed Prostate Cancer Patients With Presumed Absence of Nodal and Distant Metastases.
Study ID: NCT01769950
Brief Summary: Nodal involvement among patients with prostate cancer is known to be a poor prognostic factor. Traditionally, the presence or absence of nodal disease in patients with prostate cancer is ascertained with the use of anatomical imaging methods such as computed tomography (CT) and magnetic resonance imaging (MRI). However, the sensitivities of CT and MRI for the detection of pelvic nodal disease is rather low, with reports placing the value to lie between 50-80%. Positron emission tomography (PET) with the use of carbon-11 or fluorine-18 tagged choline (Choline-PET) is an approach which is known to deliver a high sensitivity for the imaging of prostate cancer disease burden in the primary, nodal and the metastatic areas. The investigators in this prospective trial intend to utilize Choline-PET among all newly diagnosed patients of prostate cancer who are presumed to be non-N1 (absence of nodal disease on conventional imaging) and non-M1 (absence of metastatic disease on conventional imaging).
Detailed Description:
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
HealthCare Global- Bangalore Institute of Oncology, Bengaluru, Karnataka, India
Name: Ajaikumar Basavalingaiah, MD
Affiliation: HealthCare Global- Bangalore Insititute of Oncology
Role: STUDY_CHAIR
Name: Kumar G Kallur, MD
Affiliation: HealthCare Global- Bangalore Institute of Oncology
Role: STUDY_DIRECTOR
Name: Swaroop Revannasiddaiah, MD
Affiliation: HealthCare Global- Bangalore Institute of Oncology
Role: STUDY_DIRECTOR
Name: Sandeep Muzumder, MD
Affiliation: HealthCare Global- Bangalore Institute of Oncology
Role: STUDY_DIRECTOR
Name: Govindarajan Mallarajapatna, MD
Affiliation: HealthCare Global- Bangalore Institute of Oncology
Role: STUDY_DIRECTOR
Name: Raghunath S Krishnappa, MS, DNB
Affiliation: HealthCare Global- Bangalore Institute of Oncology
Role: STUDY_DIRECTOR