Spots Global Cancer Trial Database for Ability of a New Design of Iodine 125 Seed to Maintain Intended Position When Implanted in the Prostate

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Trial Identification

Brief Title: Ability of a New Design of Iodine 125 Seed to Maintain Intended Position When Implanted in the Prostate

Official Title: A Study Assessing the Ability of AnchorSeed Iodine-125 Sources to Hold Fast in Tissue When Implanted for Treatment of Localized Prostate Cancer

Study ID: NCT01174017

Conditions

Prostate Cancer

Interventions

Iodine 125 standard loose brachytherapy seeds

AnchorSeed Iodine 125 brachytherapy prostate implant

Study Description

Brief Summary: This study compares the ability of a new design of brachytherapy seed for prostate seed implants for treatment of prostate cancer to maintain their intended position in the prostate after being deposited. Standard seeds, especially in apical locations, have a tendency to migrate distally in response to muscular forces. AnchorSeeds have a textured coating which is designed to prevent migration. 40 patients who are eligible and suitable for prostate brachytherapy will be randomly assigned to receive either standard seeds or AnchorSeeds.

Detailed Description: Standard post implant prostate brachytherapy quality assurance at the Center for the Southern Interior is usually performed at one month after the procedure with CT and MR imaging. In order to test the ability of the new design of prostate brachytherapy seeds (AnchorSeeds) to hold their position in the prostate, 40 men who have been randomly assigned to receive either standard seeds or AnchorSeeds will have an additional CT scan immediately after the procedure to record seed position for comparison to positions one month later. The magnitude and frequency of seed displacement will be determined.