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Brief Title: E3-Hormone Refractory Prostrate Cancer Taxotere Combination
Official Title: A Phase II, Double-blind, Placebo-controlled, Randomised Study to Assess the Efficacy and Safety of Docetaxel (Taxotere)/Prednisolone/ZD6474 vs Docetaxel/Prednisolone/Placebo in Patients With Hormone Refractory Prostrate Cancer (HRPC)
Study ID: NCT00498797
Brief Summary: The purpose of this study is to determine whether treatment with Zactima (vandetanib) in combination with Docetaxel and Prednisolone is more effective than the standard Docetaxel and Prednisolone alone for prostate cancer, in patients with Hormone refractory prostate cancer who have not previously received chemotherapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Research site, Rio de Janeiro, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Hamburg, , Germany
Research Site, Hannover, , Germany
Research Site, Kassel, , Germany
Research Site, Tubingen, , Germany
Research Site, Budapest, , Hungary
Research Site, Bloemfontein, , South Africa
Research Site, Cape Town, , South Africa
Research Site, Umea, , Sweden
Research Site, Uppsala, , Sweden
Name: Clinical Sciences & Operations
Affiliation: Sanofi
Role: STUDY_DIRECTOR