Spots Global Cancer Trial Database for External Beam Radiation With or Without Chemotherapy to Treat High Risk Prostate Cancer

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Trial Identification

Brief Title: External Beam Radiation With or Without Chemotherapy to Treat High Risk Prostate Cancer

Official Title: Phase 2/3 Study of Dose-escalated External Beam Radiation Therapy With or Without Chemotherapy for High Risk Adenocarcinoma of the Prostate

Study ID: NCT01603420

Conditions

Prostate Cancer

Interventions

Luteinizing hormone-releasing hormone (LHRH)

Docetaxel

Conformal Radiation Therapy (RT)

Study Description

Brief Summary: The purpose of this study is to compare the effects on prostate cancer using radiation therapy with or without chemotherapy.

Detailed Description: The recommended treatment for a high risk prostate cancer consists of a combination of radiation therapy and androgen suppression for 2-3 years. Recent studies have shown a survival advantage for chemotherapy for prostate cancer. Chemotherapy has already been successfully integrated in the treatment of other cancer types and is our belief that chemotherapy will prove to be beneficial for patients with high risk prostate cancer. However, a clinical study is necessary to compare the results good or bad of chemotherapy with radiation therapy.