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Brief Title: The ProCaRis Study: Prostate Cancer Risk Assessment in General Practice
Official Title: Prostate Cancer Risk Assessment Using Genetic Markers in General Practice
Study ID: NCT01739062
Brief Summary: The preferred method for early detection of prostate cancer (PCa) in older men with family history is the Prostate Specific Antigen test (PSA test), although the method is imprecise. It produces a high number of false-positive results and increases the risk of over-diagnosis and over-treatment. Yet, an increasing number of men get the PSA test as part of unsystematic screening. Genetic risk assessment may be a better way to identify men with low risk of PCa. The main study hypothesis is that genetic information about low risk of PCa can reduce the number of patients who get a PSA test as part of unsystematic screening.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: Yes
Department of Molecular Medicine, Aarhus N, Aarhus, Denmark
Name: Karina D Sørensen, PhD
Affiliation: Department of Molecular Medicine, Aarhus University Hospital, Denmark
Role: PRINCIPAL_INVESTIGATOR
Name: Flemming Bro, Professor
Affiliation: The Research Unit for General Practice, Aarhus University, Denmark
Role: STUDY_CHAIR
Name: Peter Vedsted, Professor
Affiliation: Danish Research Centre for Cancer Diagnosis in Primary Care, Aarhus University, Denmark
Role: STUDY_CHAIR