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Spots Global Cancer Trial Database for A Pilot Trial Using BR55 Ultrasound Contrast Agent in the Assessment of Prostate Cancer

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Trial Identification

Brief Title: A Pilot Trial Using BR55 Ultrasound Contrast Agent in the Assessment of Prostate Cancer

Official Title: A Pilot Clinical Trial Using BR55 Ultrasound Contrast Agent in the Assessment of Prostate Cancer by Molecular Imaging of VEGFR2

Study ID: NCT02142608

Conditions

Prostate Cancer

Interventions

BR55

Study Description

Brief Summary: Pilot study to evaluate the ability of BR55 to identify prostate cancer lesions with Gleason Score ≥7 by ultrasound molecular imaging on the basis of a visual score in comparison with histopathology results

Detailed Description: This multi-centre, open label, prospective, pilot study was designed to assess the ability of BR55 to detect VEGFR2 in human prostate cancer by Ultrasound Molecular Imaging (USMI). The binding of BR55 to VEGFR2 (focal enhancement still visible after significant decrease in signal from circulating microbubbles seen) was assessed at USMI and VEGFR2 expression was to be confirmed by immunohistochemistry (IHC) analysis including VEGFR2 and CD31 staining.

Eligibility

Minimum Age: 50 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: MALE

Healthy Volunteers: No

Locations

Translational Molecular Imaging Lab, Stanford, California, United States

Service d'Imagerie Diagnostique et Interventionnelle de l'Adulte, Bordeaux, , France

Contact Details

Name: Maria Luigia Storto, M.D.

Affiliation: Bracco Diagnostics, Inc

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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