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Spots Global Cancer Trial Database for ET 743 (Yondelis) in Men With Advanced Prostate Cancer

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Trial Identification

Brief Title: ET 743 (Yondelis) in Men With Advanced Prostate Cancer

Official Title: A Phase II Study of Three Hour, Weekly Infusion of ET 743 (Yondelis) in Men With Advanced Prostate Cancer

Study ID: NCT00147212

Conditions

Prostate Cancer

Interventions

ET 743

Study Description

Brief Summary: The main purpose of this study is to find out what effects (good or bad) trabectedin (ET743) has on men with advanced prostate carcinoma.

Detailed Description: * Treatment with trabectedin will be given once a week for three consecutive weeks with one week of no treatment. This four week period constitutes one cycle. * Trabectedin is given as an infusion through a central venous catheter and is administered over 3 hours. * On day 1 of each cycle a history, physical exam and blood tests will be performed and trabectedin will be administered. * On day 8 and day 15 of each cycle blood work will be performed and trabectedin will be administered. * Patients will continue to receive trabectedin as long as there is no disease progression or unacceptable side effects. * Scans (CT, MRI or bone) or x-rays may be done while the patient is on the trial at the discretion of the physician.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: MALE

Healthy Volunteers: No

Locations

Masachusetts General Hospital, Boston, Massachusetts, United States

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Contact Details

Name: Dror Michaelson, MD

Affiliation: Massachusetts General Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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