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Spots Global Cancer Trial Database for To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring

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Trial Identification

Brief Title: To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring

Official Title: A Phase II Randomized Double Blinded Study of Green Tea Catechins (GTC) vs. Placebo in Men on Active Surveillance for Prostate Cancer: Modulation of Biological and Clinical Intermediate Biomarkers

Study ID: NCT04597359

Study Description

Brief Summary: This phase II trial studies how well green tea catechins work in preventing progression of prostate cancer from a low risk stage to higher risk stages in men who are on active surveillance. Green tea catechins may stabilize prostate cancer and lower the chance of prostate growing.

Detailed Description: PRIMARY OBJECTIVE: I. To compare the change in the percent (%) Ki-67 expression in a biopsy core positive for cancer from baseline to end-of-study (EOS) biopsy between men on active surveillance (AS) for prostate cancer (PCa), treated with green tea catechins (GTCs) or placebo for 6 months. SECONDARY OBJECTIVES: I. To assess apoptosis by caspase in tumor tissue from EOS biopsy by treatment. II. To assess % Ki-67: Apoptosis ratio from EOS biopsy by treatment. III. To evaluate the number of biopsy cores positive for cancer from EOS biopsy by treatment. IV. To evaluate the percentage of any biopsy tissue core positive for cancer from EOS biopsy by treatment. V. To evaluate % Ki-67 in EOS biopsy from the same quadrant matching the quadrant with the highest % Ki-67 at baseline treatment. VI. To evaluate the Gleason sum from EOS biopsy by treatment. VII. To evaluate the change in serum prostate-specific antigen (PSA) from baseline to 3 months and to EOS by treatment. VIII. To evaluate the safety of 6 month administration of GTC assessed by Common Toxicity Criteria (CTC) version 5.0, complete blood count (CBC), comprehensive metabolic panel (CMP) and liver function toxicities (LFTs) by treatment. IX. To evaluate the change in geometric mean of % Ki-67 measures in all the cores positive for cancer from baseline to EOS biopsy by treatment. EXPLORATORY OBJECTIVES: I. To evaluate the change in catechin (epigallocatechin gallate \[EGCG\]) as indicated by change from EGCG measured in plasma from baseline and EOS by treatment. II. To evaluate the adherence and acceptability to GTC based on the percentage compliance using agent logs (%) and pill counts monthly until EOS by treatment groups. III. To evaluate the bioavailability of GTC as indicated by change from EGCG measured in plasma from baseline and EOS by treatment groups. PATIENT REPORTED OUTCOMES OBJECTIVES: I. To evaluate the change in lower urinary tract symptoms (LUTS) from baseline to 3 months and to EOS using the LUTS scale by treatment groups. II. To evaluate the change in quality of life (QOL) scores from baseline to 3 months and to EOS using the Functional Assessment of Cancer Therapy (FACT)-Prostate by treatment groups. OUTLINE: Patients are randomized to 1 of 2 arms. ARM A: Patients receive green tea catechins orally (PO) twice daily (BID) for up to 6 months in the absence of disease progression or unacceptable toxicity. ARM B: Patients receive placebo PO BID for up to 6 months. After completion of study, patients are followed up at approximately 7 days, at 6 months, and then up to 12 months.

Keywords

Eligibility

Minimum Age: 21 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Fairbanks Memorial Hospital, Fairbanks, Alaska, United States

Cancer Center at Saint Joseph's, Phoenix, Arizona, United States

Highlands Oncology Group - Fayetteville, Fayetteville, Arkansas, United States

Mercy Hospital Fort Smith, Fort Smith, Arkansas, United States

CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas, United States

CARTI Cancer Center, Little Rock, Arkansas, United States

Highlands Oncology Group - Rogers, Rogers, Arkansas, United States

Highlands Oncology Group, Springdale, Arkansas, United States

Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande, California, United States

Marshall Cancer Center, Cameron Park, California, United States

Mercy Cancer Center - Carmichael, Carmichael, California, United States

Mercy San Juan Medical Center, Carmichael, California, United States

Epic Care-Dublin, Dublin, California, United States

Mercy Cancer Center - Elk Grove, Elk Grove, California, United States

Bay Area Breast Surgeons Inc, Emeryville, California, United States

Epic Care Partners in Cancer Care, Emeryville, California, United States

Contra Costa Regional Medical Center, Martinez, California, United States

Mercy UC Davis Cancer Center, Merced, California, United States

Alta Bates Summit Medical Center - Summit Campus, Oakland, California, United States

Bay Area Tumor Institute, Oakland, California, United States

Marshall Hospital, Placerville, California, United States

Mercy Cancer Center - Rocklin, Rocklin, California, United States

Mercy Cancer Center - Sacramento, Sacramento, California, United States

Pacific Central Coast Health Center-San Luis Obispo, San Luis Obispo, California, United States

UCSF Cancer Center - San Mateo, San Mateo, California, United States

Mission Hope Medical Oncology - Santa Maria, Santa Maria, California, United States

Epic Care Cyberknife Center, Walnut Creek, California, United States

Woodland Memorial Hospital, Woodland, California, United States

Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado, United States

Rocky Mountain Regional VA Medical Center, Aurora, Colorado, United States

UCHealth University of Colorado Hospital, Aurora, Colorado, United States

Boulder Community Foothills Hospital, Boulder, Colorado, United States

Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado, United States

Rocky Mountain Cancer Centers - Centennial, Centennial, Colorado, United States

Penrose-Saint Francis Healthcare, Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado, United States

Saint Francis Cancer Center, Colorado Springs, Colorado, United States

UCHealth - Cherry Creek, Denver, Colorado, United States

The Women's Imaging Center, Denver, Colorado, United States

Porter Adventist Hospital, Denver, Colorado, United States

Colorado Blood Cancer Institute, Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown, Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose, Denver, Colorado, United States

Rose Medical Center, Denver, Colorado, United States

Mercy Medical Center, Durango, Colorado, United States

Southwest Oncology PC, Durango, Colorado, United States

Mountain Blue Cancer Care Center - Swedish, Englewood, Colorado, United States

Rocky Mountain Cancer Centers - Swedish, Englewood, Colorado, United States

Swedish Medical Center, Englewood, Colorado, United States

The Melanoma and Skin Cancer Institute, Englewood, Colorado, United States

Poudre Valley Hospital, Fort Collins, Colorado, United States

Cancer Care and Hematology-Fort Collins, Fort Collins, Colorado, United States

UCHealth Greeley Hospital, Greeley, Colorado, United States

UCHealth Highlands Ranch Hospital, Highlands Ranch, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado, United States

Saint Anthony Hospital, Lakewood, Colorado, United States

Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado, United States

Littleton Adventist Hospital, Littleton, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge, Lone Tree, Colorado, United States

Longmont United Hospital, Longmont, Colorado, United States

Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado, United States

Medical Center of the Rockies, Loveland, Colorado, United States

Parker Adventist Hospital, Parker, Colorado, United States

Saint Mary Corwin Medical Center, Pueblo, Colorado, United States

Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado, United States

MedStar Washington Hospital Center, Washington, District of Columbia, United States

Mount Sinai Comprehensive Cancer Center at Aventura, Aventura, Florida, United States

Holy Cross Hospital, Fort Lauderdale, Florida, United States

Mount Sinai Medical Center, Miami Beach, Florida, United States

Hawaii Cancer Care - Westridge, 'Aiea, Hawaii, United States

Pali Momi Medical Center, 'Aiea, Hawaii, United States

Queen's Cancer Center - Pearlridge, 'Aiea, Hawaii, United States

Straub Pearlridge Clinic, 'Aiea, Hawaii, United States

The Cancer Center of Hawaii-Pali Momi, 'Aiea, Hawaii, United States

The Queen's Medical Center - West Oahu, 'Ewa Beach, Hawaii, United States

Hawaii Cancer Care Inc - Waterfront Plaza, Honolulu, Hawaii, United States

Queen's Cancer Cenrer - POB I, Honolulu, Hawaii, United States

Queen's Medical Center, Honolulu, Hawaii, United States

Straub Clinic and Hospital, Honolulu, Hawaii, United States

University of Hawaii Cancer Center, Honolulu, Hawaii, United States

Hawaii Cancer Care Inc-Liliha, Honolulu, Hawaii, United States

Hawaii Diagnostic Radiology Services LLC, Honolulu, Hawaii, United States

Kuakini Medical Center, Honolulu, Hawaii, United States

Queen's Cancer Center - Kuakini, Honolulu, Hawaii, United States

The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii, United States

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii, United States

Straub Medical Center - Kahului Clinic, Kahului, Hawaii, United States

Castle Medical Center, Kailua, Hawaii, United States

Wilcox Memorial Hospital and Kauai Medical Clinic, Lihue, Hawaii, United States

Saint Anthony's Health, Alton, Illinois, United States

Rush - Copley Medical Center, Aurora, Illinois, United States

Illinois CancerCare-Bloomington, Bloomington, Illinois, United States

Illinois CancerCare-Canton, Canton, Illinois, United States

Memorial Hospital of Carbondale, Carbondale, Illinois, United States

SIH Cancer Institute, Carterville, Illinois, United States

Illinois CancerCare-Carthage, Carthage, Illinois, United States

Centralia Oncology Clinic, Centralia, Illinois, United States

Saint Mary's Hospital, Centralia, Illinois, United States

John H Stroger Jr Hospital of Cook County, Chicago, Illinois, United States

Carle at The Riverfront, Danville, Illinois, United States

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois, United States

Decatur Memorial Hospital, Decatur, Illinois, United States

Illinois CancerCare-Dixon, Dixon, Illinois, United States

Carle Physician Group-Effingham, Effingham, Illinois, United States

Crossroads Cancer Center, Effingham, Illinois, United States

Illinois CancerCare-Eureka, Eureka, Illinois, United States

Illinois CancerCare-Galesburg, Galesburg, Illinois, United States

Western Illinois Cancer Treatment Center, Galesburg, Illinois, United States

Ingalls Memorial Hospital, Harvey, Illinois, United States

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois, United States

Illinois CancerCare-Macomb, Macomb, Illinois, United States

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois, United States

Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States

Cancer Care Center of O'Fallon, O'Fallon, Illinois, United States

HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois, United States

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois, United States

Illinois CancerCare-Pekin, Pekin, Illinois, United States

Illinois CancerCare-Peoria, Peoria, Illinois, United States

Methodist Medical Center of Illinois, Peoria, Illinois, United States

Illinois CancerCare-Peru, Peru, Illinois, United States

Valley Radiation Oncology, Peru, Illinois, United States

Illinois CancerCare-Princeton, Princeton, Illinois, United States

Southern Illinois University School of Medicine, Springfield, Illinois, United States

Springfield Clinic, Springfield, Illinois, United States

Memorial Medical Center, Springfield, Illinois, United States

Carle Cancer Center, Urbana, Illinois, United States

The Carle Foundation Hospital, Urbana, Illinois, United States

Illinois CancerCare - Washington, Washington, Illinois, United States

Rush-Copley Healthcare Center, Yorkville, Illinois, United States

Reid Health, Richmond, Indiana, United States

Mary Greeley Medical Center, Ames, Iowa, United States

McFarland Clinic - Ames, Ames, Iowa, United States

Mission Cancer and Blood - Ankeny, Ankeny, Iowa, United States

McFarland Clinic - Boone, Boone, Iowa, United States

Saint Anthony Regional Hospital, Carroll, Iowa, United States

Medical Oncology and Hematology Associates-West Des Moines, Clive, Iowa, United States

Mercy Cancer Center-West Lakes, Clive, Iowa, United States

Alegent Health Mercy Hospital, Council Bluffs, Iowa, United States

Greater Regional Medical Center, Creston, Iowa, United States

Iowa Methodist Medical Center, Des Moines, Iowa, United States

Medical Oncology and Hematology Associates-Des Moines, Des Moines, Iowa, United States

Broadlawns Medical Center, Des Moines, Iowa, United States

Mercy Medical Center - Des Moines, Des Moines, Iowa, United States

Mission Cancer and Blood - Laurel, Des Moines, Iowa, United States

Iowa Lutheran Hospital, Des Moines, Iowa, United States

McFarland Clinic - Trinity Cancer Center, Fort Dodge, Iowa, United States

Trinity Regional Medical Center, Fort Dodge, Iowa, United States

McFarland Clinic - Jefferson, Jefferson, Iowa, United States

McFarland Clinic - Marshalltown, Marshalltown, Iowa, United States

Methodist West Hospital, West Des Moines, Iowa, United States

Mercy Medical Center-West Lakes, West Des Moines, Iowa, United States

Central Care Cancer Center - Garden City, Garden City, Kansas, United States

Central Care Cancer Center - Great Bend, Great Bend, Kansas, United States

Flaget Memorial Hospital, Bardstown, Kentucky, United States

Commonwealth Cancer Center-Corbin, Corbin, Kentucky, United States

Saint Joseph Hospital, Lexington, Kentucky, United States

Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky, United States

Saint Joseph Hospital East, Lexington, Kentucky, United States

Saint Joseph London, London, Kentucky, United States

Jewish Hospital, Louisville, Kentucky, United States

Saints Mary and Elizabeth Hospital, Louisville, Kentucky, United States

UofL Health Medical Center Northeast, Louisville, Kentucky, United States

Saint Joseph Mount Sterling, Mount Sterling, Kentucky, United States

Mercy Health - Paducah Medical Oncology and Hematology, Paducah, Kentucky, United States

Jewish Hospital Medical Center South, Shepherdsville, Kentucky, United States

Maine Medical Partners Urology, South Portland, Maine, United States

Hickman Cancer Center, Adrian, Michigan, United States

Saint Joseph Mercy Hospital, Ann Arbor, Michigan, United States

Saint Joseph Mercy Brighton, Brighton, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan, United States

Saint Joseph Mercy Canton, Canton, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan, United States

Caro Cancer Center, Caro, Michigan, United States

Saint Joseph Mercy Chelsea, Chelsea, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan, United States

Hematology Oncology Consultants-Clarkston, Clarkston, Michigan, United States

Newland Medical Associates-Clarkston, Clarkston, Michigan, United States

Ascension Saint John Hospital, Detroit, Michigan, United States

Great Lakes Cancer Management Specialists-Doctors Park, East China Township, Michigan, United States

Genesee Cancer and Blood Disease Treatment Center, Flint, Michigan, United States

Genesee Hematology Oncology PC, Flint, Michigan, United States

Genesys Hurley Cancer Institute, Flint, Michigan, United States

Hurley Medical Center, Flint, Michigan, United States

Academic Hematology Oncology Specialists, Grosse Pointe Woods, Michigan, United States

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center, Grosse Pointe Woods, Michigan, United States

Michigan Breast Specialists-Grosse Pointe Woods, Grosse Pointe Woods, Michigan, United States

University of Michigan Health - Sparrow Lansing, Lansing, Michigan, United States

Hope Cancer Clinic, Livonia, Michigan, United States

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan, United States

Great Lakes Cancer Management Specialists-Macomb Medical Campus, Macomb, Michigan, United States

Michigan Breast Specialists-Macomb Township, Macomb, Michigan, United States

Saint Mary's Oncology/Hematology Associates of Marlette, Marlette, Michigan, United States

Toledo Clinic Cancer Centers-Monroe, Monroe, Michigan, United States

21st Century Oncology-Pontiac, Pontiac, Michigan, United States

Hope Cancer Center, Pontiac, Michigan, United States

Newland Medical Associates-Pontiac, Pontiac, Michigan, United States

Saint Joseph Mercy Oakland, Pontiac, Michigan, United States

Ascension Saint Mary's Hospital, Saginaw, Michigan, United States

Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan, United States

Bhadresh Nayak MD PC-Sterling Heights, Sterling Heights, Michigan, United States

Ascension Saint Joseph Hospital, Tawas City, Michigan, United States

Advanced Breast Care Center PLLC, Warren, Michigan, United States

Great Lakes Cancer Management Specialists-Macomb Professional Building, Warren, Michigan, United States

Macomb Hematology Oncology PC, Warren, Michigan, United States

Michigan Breast Specialists-Warren, Warren, Michigan, United States

Saint John Macomb-Oakland Hospital, Warren, Michigan, United States

Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan, United States

Huron Gastroenterology PC, Ypsilanti, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan, United States

Fairview Ridges Hospital, Burnsville, Minnesota, United States

Minnesota Oncology - Burnsville, Burnsville, Minnesota, United States

Cambridge Medical Center, Cambridge, Minnesota, United States

Mercy Hospital, Coon Rapids, Minnesota, United States

Fairview Southdale Hospital, Edina, Minnesota, United States

Unity Hospital, Fridley, Minnesota, United States

Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States

Saint John's Hospital - Healtheast, Maplewood, Minnesota, United States

Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States

Hennepin County Medical Center, Minneapolis, Minnesota, United States

Health Partners Inc, Minneapolis, Minnesota, United States

Monticello Cancer Center, Monticello, Minnesota, United States

New Ulm Medical Center, New Ulm, Minnesota, United States

Fairview Northland Medical Center, Princeton, Minnesota, United States

North Memorial Medical Health Center, Robbinsdale, Minnesota, United States

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, United States

Regions Hospital, Saint Paul, Minnesota, United States

United Hospital, Saint Paul, Minnesota, United States

Saint Francis Regional Medical Center, Shakopee, Minnesota, United States

Lakeview Hospital, Stillwater, Minnesota, United States

Ridgeview Medical Center, Waconia, Minnesota, United States

Rice Memorial Hospital, Willmar, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States

Fairview Lakes Medical Center, Wyoming, Minnesota, United States

Saint Louis Cancer and Breast Institute-Ballwin, Ballwin, Missouri, United States

Central Care Cancer Center - Bolivar, Bolivar, Missouri, United States

Cox Cancer Center Branson, Branson, Missouri, United States

Saint Francis Medical Center, Cape Girardeau, Missouri, United States

Southeast Cancer Center, Cape Girardeau, Missouri, United States

Parkland Health Center - Farmington, Farmington, Missouri, United States

Capital Region Southwest Campus, Jefferson City, Missouri, United States

Freeman Health System, Joplin, Missouri, United States

Mercy Hospital Joplin, Joplin, Missouri, United States

Lake Regional Hospital, Osage Beach, Missouri, United States

Delbert Day Cancer Institute at PCRMC, Rolla, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri, United States

Heartland Regional Medical Center, Saint Joseph, Missouri, United States

Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States

Mercy Hospital South, Saint Louis, Missouri, United States

Missouri Baptist Medical Center, Saint Louis, Missouri, United States

Mercy Hospital Saint Louis, Saint Louis, Missouri, United States

Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri, United States

Mercy Hospital Springfield, Springfield, Missouri, United States

CoxHealth South Hospital, Springfield, Missouri, United States

Missouri Baptist Sullivan Hospital, Sullivan, Missouri, United States

BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri, United States

Mercy Hospital Washington, Washington, Missouri, United States

CHI Health Saint Francis, Grand Island, Nebraska, United States

CHI Health Good Samaritan, Kearney, Nebraska, United States

Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States

Alegent Health Immanuel Medical Center, Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States

Alegent Health Lakeside Hospital, Omaha, Nebraska, United States

Creighton University Medical Center, Omaha, Nebraska, United States

Midlands Community Hospital, Papillion, Nebraska, United States

New Hampshire Oncology Hematology PA-Concord, Concord, New Hampshire, United States

Solinsky Center for Cancer Care, Manchester, New Hampshire, United States

Hackensack University Medical Center, Hackensack, New Jersey, United States

Saint Peter's University Hospital, New Brunswick, New Jersey, United States

University of New Mexico Cancer Center, Albuquerque, New Mexico, United States

James J Peters VA Medical Center, Bronx, New York, United States

Elmhurst Hospital Center, Elmhurst, New York, United States

Queens Hospital Center, Jamaica, New York, United States

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States

Outer Banks Hospital, Nags Head, North Carolina, United States

Indu and Raj Soin Medical Center, Beavercreek, Ohio, United States

Saint Elizabeth Boardman Hospital, Boardman, Ohio, United States

Dayton Physicians LLC-Miami Valley South, Centerville, Ohio, United States

Miami Valley Hospital South, Centerville, Ohio, United States

Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Kenwood, Cincinnati, Ohio, United States

Bethesda North Hospital, Cincinnati, Ohio, United States

TriHealth Cancer Institute-Westside, Cincinnati, Ohio, United States

TriHealth Cancer Institute-Anderson, Cincinnati, Ohio, United States

Miami Valley Hospital, Dayton, Ohio, United States

Dayton Physician LLC-Miami Valley Hospital North, Dayton, Ohio, United States

Miami Valley Hospital North, Dayton, Ohio, United States

Armes Family Cancer Center, Findlay, Ohio, United States

Blanchard Valley Hospital, Findlay, Ohio, United States

Orion Cancer Care, Findlay, Ohio, United States

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio, United States

Dayton Physicians LLC-Atrium, Franklin, Ohio, United States

Dayton Physicians LLC-Wayne, Greenville, Ohio, United States

Wayne Hospital, Greenville, Ohio, United States

Greater Dayton Cancer Center, Kettering, Ohio, United States

Kettering Medical Center, Kettering, Ohio, United States

Toledo Clinic Cancer Centers-Maumee, Maumee, Ohio, United States

Springfield Regional Cancer Center, Springfield, Ohio, United States

Springfield Regional Medical Center, Springfield, Ohio, United States

Mercy Health - Saint Anne Hospital, Toledo, Ohio, United States

Toledo Clinic Cancer Centers-Toledo, Toledo, Ohio, United States

Dayton Physicians LLC - Troy, Troy, Ohio, United States

Upper Valley Medical Center, Troy, Ohio, United States

Saint Joseph Warren Hospital, Warren, Ohio, United States

Saint Elizabeth Youngstown Hospital, Youngstown, Ohio, United States

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma, United States

Oregon Health and Science University, Portland, Oregon, United States

Portland VA Medical Center, Portland, Oregon, United States

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania, United States

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania, United States

Pocono Medical Center, East Stroudsburg, Pennsylvania, United States

Lehigh Valley Hospital-Hazleton, Hazleton, Pennsylvania, United States

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States

Reading Hospital, West Reading, Pennsylvania, United States

Ralph H Johnson VA Medical Center, Charleston, South Carolina, United States

Medical University of South Carolina, Charleston, South Carolina, United States

Lexington Medical Center, West Columbia, South Carolina, United States

Saint Joseph Regional Cancer Center, Bryan, Texas, United States

Audie L Murphy VA Hospital, San Antonio, Texas, United States

University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

Inova Alexandria Hospital, Alexandria, Virginia, United States

Chesapeake Regional Medical Center, Chesapeake, Virginia, United States

Inova Schar Cancer Institute, Fairfax, Virginia, United States

Inova Fair Oaks Hospital, Fairfax, Virginia, United States

Inova Fairfax Hospital, Falls Church, Virginia, United States

Sovah Health Martinsville, Martinsville, Virginia, United States

VCU Massey Cancer Center at Stony Point, Richmond, Virginia, United States

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia, United States

Harrison Medical Center, Bremerton, Washington, United States

Highline Medical Center-Main Campus, Burien, Washington, United States

Saint Elizabeth Hospital, Enumclaw, Washington, United States

Saint Francis Hospital, Federal Way, Washington, United States

Saint Clare Hospital, Lakewood, Washington, United States

Jefferson Healthcare, Port Townsend, Washington, United States

Franciscan Research Center-Northwest Medical Plaza, Tacoma, Washington, United States

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin, United States

Cancer Center of Western Wisconsin, New Richmond, Wisconsin, United States

Cheyenne Regional Medical Center-West, Cheyenne, Wyoming, United States

FHP Health Center-Guam, Tamuning, , Guam

Cancer Center-Metro Medical Center Bayamon, Bayamon, , Puerto Rico

Doctors Cancer Center, Manati, , Puerto Rico

San Juan Community Oncology Group, San Juan, , Puerto Rico

Centro Comprensivo de Cancer de UPR, San Juan, , Puerto Rico

PROncology, San Juan, , Puerto Rico

San Juan City Hospital, San Juan, , Puerto Rico

Contact Details

Name: Nagi B Kumar

Affiliation: ECOG-ACRIN Cancer Research Group

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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