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Brief Title: Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion
Official Title: Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion
Study ID: NCT06315595
Brief Summary: This study evaluates contrast-enhanced MR angiography and contrast-enhanced MR perfusion imaging for the visualization of blood vessels and enhancing tissues with better spatial detail and improved temporal fidelity compared to current methods.
Detailed Description: PRIMARY OBJECTIVE: I. To study how a variety of technological approaches in MRI can be used to provide improved performance contrast-enhanced MR imaging as used for angiography and perfusion. OUTLINE: This is an observational study. Participants are assigned to 1 of 3 groups. GROUP 1: Participants undergo magnetic resonance imaging (MRI) on study. Participants may also undergo blood sample collection on study. GROUP 2: Participants receive gadolinium based MR contrast agent intravenously (IV) and undergo MRI on study. Participants may also undergo blood sample collection on study. GROUP 3: Participants receive gadolinium based MR contrast agent IV and undergo up to two MRIs on study. Participants may also undergo blood sample collection on study.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Mayo Clinic in Arizona, Scottsdale, Arizona, United States
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Name: Stephen J. Riederer, Ph.D.
Affiliation: Mayo Clinic in Rochester
Role: PRINCIPAL_INVESTIGATOR