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Spots Global Cancer Trial Database for Character Traits and Stress in Suspected Prostate Cancer

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Trial Identification

Brief Title: Character Traits and Stress in Suspected Prostate Cancer

Official Title: A Questionnaire Study by Elevated Prostate Specific Antigen (PSA): Do Men Where Subsequent Assessment Shows Prostate Cancer, Higher Levels of Neuroticism and Stress Compared to Those Who do Not Get the Diagnosis?

Study ID: NCT02031029

Interventions

Study Description

Brief Summary: It has previously been reported that men with prostate cancer are 1 ) reduced quality of life after diagnosis and treatment, 2 ) neuroticism increases the reduction in QoL related to treatment side effects, and 3) often have very involved and active spouses who seems to have been handed over / taken over parts of the men's responsibility for their own health. We postulate herein a new hypothesis that the stress level is elevated when harbouring undetected prostate cancer. We will investigate whether those who are diagnosed with prostate cancer already in beforehand have an increased degree of masculine stress ( experience of not living up to their own perception of the ideal man ) and neuroticism in the typology. We will examine different personality and QoL questionnaires for patients with elevated PSA, and compare those whose clinical assessment later reveals prostate cancer, with three control groups: 1) men with elevated PSA who are not diagnosed with prostate cancer, 2) men with normal PSA treated for benign prostate enlargement and 3) patient with substantial risk of colorectal cancer (CRC) who undergo colonoscopy, with regard to increased level of masculine stress and the personality trait neuroticism.

Detailed Description: Inclusion criteria: 1. Men who are being referred as new urological outpatient and meet the following criteria: 1. Wanted clinical examined because of elevated PSA 2. Not strong family history of prostate cancer 3. It is taken biopsy as part of routine investigation. 2. Control groups: Men being referred to urological / gastroenterological outpatient clinic, and which meet the following criteria: 1. urination complaints, normal PSA, and study shows prostate size\> 40cc 2. Or melena and cancer suspicion in colorectum 3. Age\> 18 years and \<75 years Outcome measures: Together with statistician look for patterns / covariance in replies from those who are diagnosed with prostate cancer in the questionnaires personality evaluation adapted to normal population (Neo-FFI), gender differentiated stress response questionnaire (MGRSS) and questionnaires related to resilience, relationship and quality of life index, compared with the control groups.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: MALE

Healthy Volunteers: Yes

Locations

Akershus University Hospital, Lørenskog, , Norway

Stavanger University Hospital, urological department, Stavanger, , Norway

Contact Details

Name: Gunn Iren Meling, MD PhD

Affiliation: Helse Stavanger HF

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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