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Brief Title: Intratumoral Bromelain + Acetylcysteine in Relapsed and Unresectable Pseudomyxoma Peritonei
Official Title: Intratumoral Bromelain + N-acetylcysteine in Relapsed and Unresectable Pseudomyxoma Peritonei. Phase I Single-arm Trial
Study ID: NCT04982146
Brief Summary: This trial pursues studying a compassionate treatment option for patients with inoperable pseudomyxoma peritonei through percutaneous administration of bromelain + N-acetylcysteine (NAC) in order to decrease tumoral volume. Secondary endpoints are the decrease of ascites, compressive symptoms and pain through the dilution of mucins, which would better intestinal blockage.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Hospital Universitario Reina SofĂa, CĂłrdoba, , Spain
Name: Lidia RodrĂguez Ortiz, MD
Affiliation: Hospital Universitario Reina SofĂa
Role: PRINCIPAL_INVESTIGATOR
Name: Ălvaro Arjona SĂĄnchez, PhD
Affiliation: Hospital Universitario Reina SofĂa
Role: PRINCIPAL_INVESTIGATOR