Spots Global Cancer Trial Database for Leflunomide in Patients With PTEN-null Advanced Solid Malignancies
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Trial Identification
Brief Title: Leflunomide in Patients With PTEN-null Advanced Solid Malignancies
Official Title: A Phase IA/IB Trial of Leflunomide in Patients With PTEN-null Advanced Solid Malignancies
Study ID: NCT04997993
Conditions
Interventions
Study Description
Brief Summary: Leflunomide in patients with PTEN-null advanced solid tumors. Objectives are to determine the safety and tolerability and the MTD of leflunomide in patients with PTEN-null advanced solid malignancies and to assess preliminary evidence of clinical activity of leflunomide in patients with PTEN-null advanced solid malignancies.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Icahn School of Medicine at Mount Sinai, New York, New York, United States
Contact Details
Name: Deborah Doroshow, MD, PhD
Affiliation: Icahn School of Medicine at Mount Sinai
Role: PRINCIPAL_INVESTIGATOR
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