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Brief Title: Almonertinib as First-line Treatment in Patients With EGFR+ Positive Pulmonary Adenosquamous Carcinoma or Combined Adenocarcinoma and Squamous Cell Carcinoma
Official Title: Aumolertinib as First-line Treatment in EGFR-Mutant Pulmonary Adenosquamous Carcinoma: A Multicenter, Single-Arm, Prospective Study (ARISE)
Study ID: NCT04354961
Brief Summary: This is a prospective, multi-center, single-arm clinical trial.
Detailed Description: This is a multicenter, single arm, phase II study assessing the efficacy and safety of Almonertinib as first-line treatment in patients with EGFR mutation positive locally advanced or metastatic Pulmonary Adenosquamous Carcinoma.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Beijing Cancer Hospital, Beijing, , China
Beijing Chest Hospital, Capital Medical University, Beijing, , China
Cancer Hospital Chinese Academy of Medical Sciences, Beijing, , China
Hunan Cancer Hospital, Changsha, , China
The Second Xiangya Hospital of Central South University, Changsha, , China
Xinqiao Hospital, Army Medical University, Chongqing, , China
Fujian Cancer Hospital, Fuzhou, , China
Fujian Provincial Hospital, Fuzhou, , China
Sir Run Run Shaw Hospital, Hangzhou, , China
The second Affiliated Hospital of Kunming Medical University, Kunming, , China
The second Affiliated Hospital of Nanchang University, Nanchang, , China
Jiangsu Province Hospital, Nanjing, , China
Shanghai Chest Hospital, Shanghai, , China
Tianjin Medical University Cancer Institute & Hospital, Tianjin, , China
Tongji Hospital of Tongji Medical College,Huazhong University of Science and Technology, Wuhan, , China
Air Force Medical University of PLA (the Fourth Military Medical University), Xi'an, , China
Henan Cancer Hospital, Zhengzhou, , China
Henan Provincial People's Hospital, Zhengzhou, , China