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Brief Title: Contrast Echocardiography in Patients With Pulmonary Arteriovenous Malformations (PAVMs)
Official Title: The Evaluation of Intra-cardiac Shunts in Patients With Pulmonary Arteriovenous Malformations
Study ID: NCT00733759
Brief Summary: Pulmonary arteriovenous malformations (PAVMs) are thin-walled abnormal vessels which provide direct capillary-free communications between the pulmonary and systemic circulations. Patients with PAVMs have usually have low blood oxygen levels and are at risk of other complications including strokes, brain abscesses, pregnancy-related complications and haemorrhage. We hypothesise that the complications of PAVM patients arise from their PAVMs and not the more recognised intracardiac forms of shunting. We propose to perform echocardiograms to enable assessment of the presence of other causes of capillary-free communications between the pulmonary and systemic circulations.
Detailed Description:
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Imperial College Hammersmith Campus, London, , United Kingdom
Name: Claire L Shovlin
Affiliation: Imperial College London
Role: PRINCIPAL_INVESTIGATOR