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Brief Title: Fluorescence-navigated Thoracoscopy for Detection of Small Pulmonary Nodules
Official Title: Fluorescence-navigated Thoracoscopy for Detection of Small Pulmonary Nodules
Study ID: NCT04165603
Brief Summary: Fluorescence-navigated thoracoscopic imaging with indocyanine green (ICG) is a novel technique for detection of small pulmonary nodules other than traditional radiography or intraoperative palpation. As a non-targeted fluorescent contrast agent, ICG accumulates in tumors by the enhanced permeability and retention effect (EPR), making the lesions fluoresce under fluorescent imaging. However, the optimal dosage and injection time of ICG are still under exploration. Hence, we perform this study in humans made up of four groups to determine the optimal time and dose.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Peking University People's Hospital, Beijing, Beijing, China
Name: Wang Jun, MD
Affiliation: Peking University People's Hospital
Role: STUDY_DIRECTOR