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Brief Title: Safety and Efficacy Study of Panzem NCD to Treat Glioblastoma
Official Title: A Single-Center, Open-Label, Phase II, Safety, Pharmacokinetic and Efficacy of Panzem Nanocrystal Colloidal Dispersion Administered Orally to Patients With Recurrent Glioblastoma Multiforme
Study ID: NCT00306618
Brief Summary: This single-center, open-label, phase 2 study will evaluate the anti-tumor activity, as well as the safety and pharmacokinetics, of Panzem (2-methoxyestradiol, 2ME2) Nanocrystal Colloidal Dispersion (NCD) administered in patients with recurrent glioblastoma multiforme (GBM)
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States
Name: David A. Reardon, M.D.
Affiliation: The Brain Center at Duke, Duke University Medical Center
Role: PRINCIPAL_INVESTIGATOR