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Brief Title: LITT Combined With Early Use of Temozolomide for Recurrent Glioblastomas
Official Title: Safety and Efficacy of LITT Combined With Early Use of Temozolomide for Recurrent Glioblastomas
Study ID: NCT05663125
Brief Summary: This study aims to investigate the safety and efficacy of Laser Interstitial Thermal Therapy (LITT) combined with postoperative early use of temozolomide in treating recurrent glioblastomas.
Detailed Description: This is an open-label, non-randomized Phase II study, planning to recruit about ten patients. The primary objective of this study is to investigate the safety of MRI-guided LITT in combination with the early application of temozolomide. The secondary outcome is to explore the efficacy of MRI-guided LITT combined with the early use of temozolomide in treating recurrent glioblastomas.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Beijing Tiantan Hospital, Beijing, , China
Name: Dabiao Zhou, MD
Affiliation: Beijing Tiantan Hospital
Role: PRINCIPAL_INVESTIGATOR