Spots Global Cancer Trial Database for Trabectedin for Recurrent Grade II/III Meningioma
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Trial Identification
Brief Title: Trabectedin for Recurrent Grade II/III Meningioma
Official Title: Trabectedin for Recurrent Grade II or III Meningioma: a Randomized Phase II Study of the EORTC Brain Tumor Group
Study ID: NCT02234050
Conditions
Study Description
Brief Summary: The aim of this study is to collect data on activity, toxicity and quality of life of trabectedin therapy in patients with recurrent high-grade meningioma.
Detailed Description: This is a randomized open label multicenter comparative phase II trial. The objective of the study is to investigate whether trabectedin demonstrates sufficient antitumor activity against recurrent grade II or III to justify further investigation in phase III or as adjuvant therapy for newly diagnosed disease after resection and radiotherapy.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Landesnervenklinik Wagner Jauregg, Linz, , Austria
Medical University Vienna - General Hospital AKH, Vienna, , Austria
Hopitaux Universitaires Bordet-Erasme - Hopital Universitaire Erasme, Brussels, , Belgium
Universitair Ziekenhuis Antwerpen, Edegem, , Belgium
Universitair Ziekenhuis Gent, Gent, , Belgium
U.Z. Leuven - Campus Gasthuisberg, Leuven, , Belgium
CHU Dinant Godinne - UCL Namur, Yvoir, , Belgium
CHU de Bordeaux - Groupe Hospitalier Saint-André - Hopital Saint-Andre, Bordeaux, , France
CHU de Lyon - CHU Lyon - Hopital neurologique Pierre Wertheimer, Bron, , France
Centre Georges-Francois-Leclerc, Dijon, , France
CHRU de Lille, Lille, , France
Centre Leon Berard, Lyon, , France
Institut régional du Cancer Montpellier, Montpellier, , France
CHU de Nice - Hopital Pasteur, Nice, , France
Assistance Publique - Hopitaux de Paris - La Pitie Salpetriere, Paris, , France
Centre Eugene Marquis, Rennes, , France
Gustave Roussy, Villejuif, , France
Universitaetsklinikum Bonn, Bonn, , Germany
Universitaetsklinikum - Essen, Essen, , Germany
Klinikum Der J.W. Goethe Universitaet, Frankfurt, , Germany
Universitaetsklinikum Freiburg - Klinik fuer Neurochirurgie, Freiburg, , Germany
Universitaetsklinikum Heidelberg - UniversitaetsKlinikum Heidelberg - Head Hospital, Heidelberg, , Germany
Universitaetsklinikum Leipzig, Leipzig, , Germany
Ludwig-Maximilians-Universitaet Muenchen - Klinikum der Universitaet Muenchen - Campus Grosshadern, Muenchen, , Germany
Universitaetsklinikum Muenster, Zentralklinikum, Muenster, , Germany
Universitaetskliniken Regensburg, Regensburg, , Germany
Eberhard Karls Universitaet Tuebingen - Universitaetsklinikum Tuebingen, Tubingen, , Germany
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, , Italy
Ospedale San Raffaele, Milano, , Italy
Istituto Oncologico Veneto IRCCS - Ospedale Busonera, Padova, , Italy
Istituto Regina Elena / Istituti Fisioterapici Ospitalieri, Roma, , Italy
Azienda Ospedaliera Città della Salute e della Scienza di Torino - Ospedale San Giovanni - Dipartimento Neuroscienze, Torino, , Italy
Spaarne Gasthuis - Vrije Universiteit Medisch Centrum, Amsterdam, , Netherlands
University Medical Center Groningen, Groningen, , Netherlands
Erasmus MC Cancer Institute - location Daniel den Hoed, Rotterdam, , Netherlands
Oslo University Hospital - Radiumhospitalet, Oslo, , Norway
Hospital Clinic Universitari de Barcelona, Barcelona, , Spain
Hospital De La Santa Creu I Sant Pau, Barcelona, , Spain
Institut Catala d'Oncologia - ICO Badalona - Hospital Germans Trias i Pujol (Institut Catala D'Oncologia), Barcelona, , Spain
Institut Catala d'Oncologia - ICO L'Hospitalet - Hospital Duran i Reynals (Institut Catala D'Oncologia), L'Hospitalet de Llobregat, , Spain
Hospital Universitario 12 De Octubre, Madrid, , Spain
Centre Hospitalier Universitaire Vaudois - Lausanne, Lausanne, , Switzerland
UniversitaetsSpital Zurich, Zurich, , Switzerland
University Hospitals Bristol NHS Foundation Trust - Bristol Haematology And Oncology Centre, Bristol, , United Kingdom
NHS Lothian - Western General Hospital, Edinburgh, , United Kingdom
Guy's and St Thomas' NHS - St Thomas Hospital, London, , United Kingdom
Newcastle Hospitals NHS Trust - Freeman Hospital, Northern Centre For Cancer Care, Newcastle, , United Kingdom
Contact Details
Name: Matthias Preusser
Affiliation: Medical University Vienna - General Hospital AKH
Role: STUDY_CHAIR
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