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Spots Global Cancer Trial Database for Human Papillomatosis Genotyping of Children in Thailand

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Trial Identification

Brief Title: Human Papillomatosis Genotyping of Children in Thailand

Official Title: Human Papillomatosis Genotyping and Severity in Patients With Recurrent Respiratory Papillomatosis of Children in Thailand

Study ID: NCT01304966

Interventions

biopsy

Study Description

Brief Summary: The purpose of the present study was to identify risk factors for more severe juvenile Recurrent Respiratory Papillomatosis (RRP) through prospective evaluation of a pediatric population in Thailand by the employing a protocol that includes staging of disease severity using above mentioned staging system at the time of each endoscopic debridement, as well as human papilloma virus (HPV) genotyping.

Detailed Description: Recurrent respiratory papillomatosis is caused by human papilloma virus and is the most common benign laryngeal neoplasm in children. Although RRP is rarely fatal, the disease requires prolonged, extensive medical and surgical treatment, and causes physical and emotional suffering in affected children and their families. Although recurrent respiratory papillomatosis is a relatively unusual problem, it accounts for significant health are expenditures.The goal of management of RRP is control of the disease, preservation of the voice and prevention of major complication .The purpose of study will identify risk factors for more severe juvenile RRP through prospective evaluation of a pediatric population in Thailand by the employing a protocol that includes staging of disease severity , as well as HPV genotyping. Objective: * To identify the genotypes of HPV isolated from Thai RRP patients * To compare staging and severity with HPV genotypes * To correlate the following characteristics of the Thai RRP patients with the HPV genotypes

Keywords

Eligibility

Minimum Age:

Eligible Ages: CHILD, ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Department of Otorhinolaryngology: Queen Sirikit National of Child Health, Bangkok, , Thailand

Queen Sirikit National Institute of Child Health, Bangkok, , Thailand

Contact Details

Name: Pavinee Intakorn, MD

Affiliation: Queen Sirikit National Institute of Child Health

Role: PRINCIPAL_INVESTIGATOR

Name: Pavinee Intakorn, MD

Affiliation: Queen Sirikit National of Child Health

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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