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Spots Global Cancer Trial Database for Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

Official Title: Maintenance Systemic Therapy Versus Local Consolidative Therapy (LCT) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II/III Trial

Study ID: NCT03137771

Study Description

Brief Summary: This randomized phase II/III trial studies how well giving maintenance chemotherapy with or without local consolidation therapy works in treating patients with stage IV non-small cell lung cancer. Drugs used in maintenance chemotherapy, such as docetaxel, pemetrexed disodium, erlotinib hydrochloride, and gemcitabine work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Local consolidation therapy such as radiation/stereotactic body radiation or surgery may kill cancer cells left after initial treatment. Giving maintenance chemotherapy and local consolidation therapy together may work better than maintenance chemotherapy alone in treating patients with stage IV non-small cell lung cancer.

Detailed Description: PRIMARY OBJECTIVES: Phase II To evaluate the impact of adding local consolidative therapy (LCT) to maintenance systemic therapy versus maintenance systemic therapy alone on progression-free survival for patients with metastatic non-small cell lung cancer (NSCLC) with no evidence of progression and limited metastatic sites after first-line systemic therapy. Phase III To evaluate the impact of adding LCT to maintenance systemic therapy versus maintenance systemic therapy alone on overall survival for patients with metastatic NSCLC with no evidence of progression and limited metastatic sites after first-line systemic therapy. SECONDARY OBJECTIVES: I. To evaluate the impact of adding LCT to maintenance systemic therapy versus maintenance systemic therapy alone on in-field local failure. II. To evaluate the impact of adding LCT to maintenance systemic therapy versus maintenance systemic therapy alone on the time to development of new lesions. III. To evaluate the impact of adding LCT to maintenance systemic therapy versus maintenance systemic therapy alone on toxicity. IV. To evaluate the impact of adding LCT to maintenance systemic therapy versus maintenance systemic therapy alone on duration of maintenance systemic therapy usage. V. To evaluate the effect of adding LCT to systemic therapy in limited stage IV NSCLC on Quality of Life (QOL) VI. To collect biospecimens and evaluate the correlation between clinical outcomes and circulating tumor DNA (ctDNA). OUTLINE: Patients are randomized into 1 of 2 arms. ARM 1 (CHEMOTHERAPY ALONE): ): Patients may receive docetaxel intravenously (IV) over 60 minutes on Day 1, erlotinib hydrochloride orally (PO) once daily (QD), or gemcitabine IV over 30 minutes on Days 1 and 8. Patients with non-squamous non-small cell lung cancer may receive pemetrexed disodium IV over 10 minutes on Day 1 alone or in combination with pembrolizumab IV over 30 minutes. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity. ARM 2 (SBRT AND CHEMOTHERAPY): Patients undergo LCT over 2-4 weeks. If LCT cannot be used to treat primary disease sites, patients also undergo intensity-modulated radiation therapy (IMRT) or 3-dimensional conformal radiation therapy (3DCRT) over 3-5 weeks. Within 2 weeks after completion of radiation therapy, patients receive chemotherapy as in Arm 1. Patients may possibly undergo surgery. After completion of study treatment, patients are followed up every 3 months for 2 years, every 6 months for 3 years, then annually thereafter.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States

Arizona Breast Cancer Specialists-Gilbert, Gilbert, Arizona, United States

Arizona Center for Cancer Care-Peoria, Peoria, Arizona, United States

Mayo Clinic Hospital in Arizona, Phoenix, Arizona, United States

Arizona Breast Cancer Specialists-Scottsdale, Scottsdale, Arizona, United States

Mayo Clinic in Arizona, Scottsdale, Arizona, United States

University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona, United States

Banner University Medical Center - Tucson, Tucson, Arizona, United States

University of Arizona Cancer Center-North Campus, Tucson, Arizona, United States

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California, United States

City of Hope Comprehensive Cancer Center, Duarte, California, United States

UC San Diego Moores Cancer Center, La Jolla, California, United States

Los Angeles County-USC Medical Center, Los Angeles, California, United States

USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States

Memorial Medical Center, Modesto, California, United States

Saint Joseph Hospital - Orange, Orange, California, United States

The Permanente Medical Group-Roseville Radiation Oncology, Roseville, California, United States

Sutter Medical Center Sacramento, Sacramento, California, United States

University of California Davis Comprehensive Cancer Center, Sacramento, California, United States

Saint Helena Hospital, Saint Helena, California, United States

Salinas Valley Memorial, Salinas, California, United States

City of Hope South Pasadena, South Pasadena, California, United States

Kaiser Permanente Cancer Treatment Center, South San Francisco, California, United States

Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, California, United States

Penrose-Saint Francis Healthcare, Colorado Springs, Colorado, United States

UCHealth Memorial Hospital Central, Colorado Springs, Colorado, United States

Porter Adventist Hospital, Denver, Colorado, United States

Poudre Valley Hospital, Fort Collins, Colorado, United States

Yale University, New Haven, Connecticut, United States

Helen F Graham Cancer Center, Newark, Delaware, United States

Beebe Health Campus, Rehoboth Beach, Delaware, United States

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida, United States

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida, United States

University of Florida Health Science Center - Gainesville, Gainesville, Florida, United States

Mayo Clinic in Florida, Jacksonville, Florida, United States

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida, United States

Miami Cancer Institute, Miami, Florida, United States

UM Sylvester Comprehensive Cancer Center at Kendall, Miami, Florida, United States

Orlando Health Cancer Institute, Orlando, Florida, United States

UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida, United States

Tallahassee Memorial HealthCare, Tallahassee, Florida, United States

Moffitt Cancer Center, Tampa, Florida, United States

Cleveland Clinic-Weston, Weston, Florida, United States

Grady Health System, Atlanta, Georgia, United States

Emory University Hospital Midtown, Atlanta, Georgia, United States

Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, United States

Emory Saint Joseph's Hospital, Atlanta, Georgia, United States

Augusta University Medical Center, Augusta, Georgia, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia, United States

Queen's Medical Center, Honolulu, Hawaii, United States

The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii, United States

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho, United States

Northwestern University, Chicago, Illinois, United States

Rush University Medical Center, Chicago, Illinois, United States

University of Illinois, Chicago, Illinois, United States

Decatur Memorial Hospital, Decatur, Illinois, United States

Crossroads Cancer Center, Effingham, Illinois, United States

Western Illinois Cancer Treatment Center, Galesburg, Illinois, United States

Edward Hines Jr VA Hospital, Hines, Illinois, United States

Condell Memorial Hospital, Libertyville, Illinois, United States

Loyola University Medical Center, Maywood, Illinois, United States

Advocate Lutheran General Hospital, Park Ridge, Illinois, United States

Methodist Medical Center of Illinois, Peoria, Illinois, United States

OSF Saint Francis Medical Center, Peoria, Illinois, United States

SwedishAmerican Regional Cancer Center/ACT, Rockford, Illinois, United States

Memorial Medical Center, Springfield, Illinois, United States

Southwest Illinois Health Services LLP, Swansea, Illinois, United States

Carle Cancer Center, Urbana, Illinois, United States

Parkview Hospital Randallia, Fort Wayne, Indiana, United States

Parkview Regional Medical Center, Fort Wayne, Indiana, United States

Goshen Center for Cancer Care, Goshen, Indiana, United States

Community Cancer Center East, Indianapolis, Indiana, United States

Community Cancer Center South, Indianapolis, Indiana, United States

Franciscan Health Indianapolis, Indianapolis, Indiana, United States

Community Cancer Center North, Indianapolis, Indiana, United States

Franciscan Health Mooresville, Mooresville, Indiana, United States

Mercy Cancer Center-West Lakes, Clive, Iowa, United States

Iowa Methodist Medical Center, Des Moines, Iowa, United States

Mercy Medical Center - Des Moines, Des Moines, Iowa, United States

University of Kansas Cancer Center, Kansas City, Kansas, United States

Lawrence Memorial Hospital, Lawrence, Kansas, United States

University of Kansas Cancer Center-Overland Park, Overland Park, Kansas, United States

Ascension Via Christi Hospitals Wichita, Wichita, Kansas, United States

Saint Elizabeth Healthcare Edgewood, Edgewood, Kentucky, United States

University of Kentucky/Markey Cancer Center, Lexington, Kentucky, United States

Norton Hospital Pavilion and Medical Campus, Louisville, Kentucky, United States

The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky, United States

Norton Brownsboro Hospital and Medical Campus, Louisville, Kentucky, United States

LSU Health Baton Rouge-North Clinic, Baton Rouge, Louisiana, United States

Louisiana Hematology Oncology Associates LLC, Baton Rouge, Louisiana, United States

Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, United States

Our Lady of the Lake Physicians Group - Medical Oncology, Baton Rouge, Louisiana, United States

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland, United States

Central Maryland Radiation Oncology in Howard County, Columbia, Maryland, United States

UM Baltimore Washington Medical Center/Tate Cancer Center, Glen Burnie, Maryland, United States

TidalHealth Richard A Henson Cancer Institute, Ocean Pines, Maryland, United States

TidalHealth Peninsula Regional, Salisbury, Maryland, United States

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

Brigham and Women's Hospital, Boston, Massachusetts, United States

Boston Medical Center, Boston, Massachusetts, United States

Lahey Hospital and Medical Center, Burlington, Massachusetts, United States

McLaren Cancer Institute-Bay City, Bay City, Michigan, United States

McLaren Cancer Institute-Clarkston, Clarkston, Michigan, United States

Henry Ford Macomb Hospital-Clinton Township, Clinton Township, Michigan, United States

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan, United States

Henry Ford Hospital, Detroit, Michigan, United States

Ascension Saint John Hospital, Detroit, Michigan, United States

Weisberg Cancer Treatment Center, Farmington Hills, Michigan, United States

McLaren Cancer Institute-Flint, Flint, Michigan, United States

Singh and Arora Hematology Oncology PC, Flint, Michigan, United States

Allegiance Health, Jackson, Michigan, United States

West Michigan Cancer Center, Kalamazoo, Michigan, United States

Karmanos Cancer Institute at McLaren Greater Lansing, Lansing, Michigan, United States

Mid-Michigan Physicians-Lansing, Lansing, Michigan, United States

Sparrow Hospital, Lansing, Michigan, United States

McLaren Cancer Institute-Lapeer Region, Lapeer, Michigan, United States

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan, United States

McLaren Cancer Institute-Macomb, Mount Clemens, Michigan, United States

McLaren Cancer Institute-Northern Michigan, Petoskey, Michigan, United States

21st Century Oncology-Pontiac, Pontiac, Michigan, United States

McLaren-Port Huron, Port Huron, Michigan, United States

William Beaumont Hospital-Royal Oak, Royal Oak, Michigan, United States

Ascension Saint Mary's Hospital, Saginaw, Michigan, United States

William Beaumont Hospital - Troy, Troy, Michigan, United States

Saint John Macomb-Oakland Hospital, Warren, Michigan, United States

University of Michigan Health - West, Wyoming, Michigan, United States

Sanford Joe Lueken Cancer Center, Bemidji, Minnesota, United States

Saint Luke's Hospital of Duluth, Duluth, Minnesota, United States

Hennepin County Medical Center, Minneapolis, Minnesota, United States

Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota, United States

Regions Hospital, Saint Paul, Minnesota, United States

Saint Francis Medical Center, Cape Girardeau, Missouri, United States

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri, United States

Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, United States

Delbert Day Cancer Institute at PCRMC, Rolla, Missouri, United States

Washington University School of Medicine, Saint Louis, Missouri, United States

Missouri Baptist Medical Center, Saint Louis, Missouri, United States

Mercy Hospital Saint Louis, Saint Louis, Missouri, United States

Mercy Hospital Springfield, Springfield, Missouri, United States

Bozeman Deaconess Hospital, Bozeman, Montana, United States

Saint James Community Hospital and Cancer Treatment Center, Butte, Montana, United States

Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana, United States

Kalispell Regional Medical Center, Kalispell, Montana, United States

Nebraska Methodist Hospital, Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States

Renown Regional Medical Center, Reno, Nevada, United States

Wentworth-Douglass Hospital, Dover, New Hampshire, United States

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire, United States

Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth, Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen, Montvale, New Jersey, United States

Virtua Samson Cancer Center, Moorestown, New Jersey, United States

Virtua Memorial, Mount Holly, New Jersey, United States

Community Medical Center, Toms River, New Jersey, United States

Virtua Voorhees, Voorhees, New Jersey, United States

Lovelace Medical Center-Saint Joseph Square, Albuquerque, New Mexico, United States

University of New Mexico Cancer Center, Albuquerque, New Mexico, United States

Lovelace Radiation Oncology, Albuquerque, New Mexico, United States

Christus Saint Vincent Regional Cancer Center, Santa Fe, New Mexico, United States

Montefiore Medical Center-Einstein Campus, Bronx, New York, United States

Montefiore Medical Center - Moses Campus, Bronx, New York, United States

New York-Presbyterian/Brooklyn Methodist Hospital, Brooklyn, New York, United States

Memorial Sloan Kettering Commack, Commack, New York, United States

Memorial Sloan Kettering Westchester, Harrison, New York, United States

Mount Sinai West, New York, New York, United States

Mount Sinai Hospital, New York, New York, United States

Memorial Sloan Kettering Cancer Center, New York, New York, United States

University of Rochester, Rochester, New York, United States

Stony Brook University Medical Center, Stony Brook, New York, United States

State University of New York Upstate Medical University, Syracuse, New York, United States

Memorial Sloan Kettering Nassau, Uniondale, New York, United States

Dickstein Cancer Treatment Center, White Plains, New York, United States

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina, United States

Atrium Health Pineville/LCI-Pineville, Charlotte, North Carolina, United States

Atrium Health University City/LCI-University, Charlotte, North Carolina, United States

Atrium Health Cabarrus/LCI-Concord, Concord, North Carolina, United States

Duke University Medical Center, Durham, North Carolina, United States

Atrium Health Union/LCI-Union, Monroe, North Carolina, United States

CarolinaEast Medical Center, New Bern, North Carolina, United States

Novant Cancer Institute Radiation Oncology - Supply, Supply, North Carolina, United States

Novant Health Cancer Institute Radiation Oncology - Wilmington, Wilmington, North Carolina, United States

Novant Health New Hanover Regional Medical Center, Wilmington, North Carolina, United States

Sanford Bismarck Medical Center, Bismarck, North Dakota, United States

Sanford Roger Maris Cancer Center, Fargo, North Dakota, United States

Altru Cancer Center, Grand Forks, North Dakota, United States

Cleveland Clinic Akron General, Akron, Ohio, United States

UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio, United States

Geauga Hospital, Chardon, Ohio, United States

Adena Regional Medical Center, Chillicothe, Ohio, United States

University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio, United States

Case Western Reserve University, Cleveland, Ohio, United States

Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio, United States

Cleveland Clinic Foundation, Cleveland, Ohio, United States

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

The Mark H Zangmeister Center, Columbus, Ohio, United States

Cleveland Clinic Cancer Center Mansfield, Mansfield, Ohio, United States

Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio, United States

UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio, United States

UH Seidman Cancer Center at Southwest General Hospital, Middleburg Heights, Ohio, United States

University Hospitals Parma Medical Center, Parma, Ohio, United States

University Hospitals Portage Medical Center, Ravenna, Ohio, United States

North Coast Cancer Care, Sandusky, Ohio, United States

UH Seidman Cancer Center at Firelands Regional Medical Center, Sandusky, Ohio, United States

ProMedica Flower Hospital, Sylvania, Ohio, United States

University of Cincinnati Cancer Center-West Chester, West Chester, Ohio, United States

UH Seidman Cancer Center at Saint John Medical Center, Westlake, Ohio, United States

UHHS-Westlake Medical Center, Westlake, Ohio, United States

Cleveland Clinic Wooster Family Health and Surgery Center, Wooster, Ohio, United States

Genesis Healthcare System Cancer Care Center, Zanesville, Ohio, United States

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma, United States

Good Samaritan Hospital, Corvallis, Oregon, United States

Legacy Mount Hood Medical Center, Gresham, Oregon, United States

Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon, United States

Providence Portland Medical Center, Portland, Oregon, United States

Providence Saint Vincent Medical Center, Portland, Oregon, United States

Bryn Mawr Hospital, Bryn Mawr, Pennsylvania, United States

Geisinger Medical Center, Danville, Pennsylvania, United States

Delaware County Memorial Hospital, Drexel Hill, Pennsylvania, United States

Northeast Radiation Oncology Center, Dunmore, Pennsylvania, United States

Saint Vincent Hospital, Erie, Pennsylvania, United States

UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg, Pennsylvania, United States

Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, United States

Lancaster General Ann B Barshinger Cancer Institute, Lancaster, Pennsylvania, United States

Lancaster General Hospital, Lancaster, Pennsylvania, United States

Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania, United States

Lewistown Hospital, Lewistown, Pennsylvania, United States

Paoli Memorial Hospital, Paoli, Pennsylvania, United States

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

Jefferson Torresdale Hospital, Philadelphia, Pennsylvania, United States

Geisinger Cancer Services-Pottsville, Pottsville, Pennsylvania, United States

Guthrie Medical Group PC-Robert Packer Hospital, Sayre, Pennsylvania, United States

Reading Hospital, West Reading, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania, United States

Asplundh Cancer Pavilion, Willow Grove, Pennsylvania, United States

Lankenau Medical Center, Wynnewood, Pennsylvania, United States

Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina, United States

Prisma Health Cancer Institute - Faris, Greenville, South Carolina, United States

Saint Francis Cancer Center, Greenville, South Carolina, United States

Prisma Health Cancer Institute - Eastside, Greenville, South Carolina, United States

Self Regional Healthcare, Greenwood, South Carolina, United States

Prisma Health Cancer Institute - Greer, Greer, South Carolina, United States

Gibbs Cancer Center-Pelham, Greer, South Carolina, United States

The Radiation Oncology Center-Hilton Head/Bluffton, Hilton Head Island, South Carolina, United States

Prisma Health Cancer Institute - Seneca, Seneca, South Carolina, United States

Spartanburg Medical Center, Spartanburg, South Carolina, United States

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota, United States

Baptist Memorial Hospital and Cancer Center-Memphis, Memphis, Tennessee, United States

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas, United States

UT Southwestern/Simmons Cancer Center-Fort Worth, Fort Worth, Texas, United States

University of Texas Medical Branch, Galveston, Texas, United States

M D Anderson Cancer Center, Houston, Texas, United States

Covenant Medical Center-Lakeside, Lubbock, Texas, United States

University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah, United States

George E Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, United States

Norris Cotton Cancer Center-North, Saint Johnsbury, Vermont, United States

VCU Massey Cancer Center at Stony Point, Richmond, Virginia, United States

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia, United States

Legacy Salmon Creek Hospital, Vancouver, Washington, United States

West Virginia University Healthcare, Morgantown, West Virginia, United States

Langlade Hospital and Cancer Center, Antigo, Wisconsin, United States

Ascension Saint Elizabeth Hospital, Appleton, Wisconsin, United States

Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin, United States

Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin, United States

Aurora Health Center-Fond du Lac, Fond Du Lac, Wisconsin, United States

Aurora Health Care Germantown Health Center, Germantown, Wisconsin, United States

Aurora Cancer Care-Grafton, Grafton, Wisconsin, United States

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin, United States

Aurora BayCare Medical Center, Green Bay, Wisconsin, United States

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin, United States

Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin, United States

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin, United States

Froedtert Menomonee Falls Hospital, Menomonee Falls, Wisconsin, United States

Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin, United States

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin, United States

Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Aurora Sinai Medical Center, Milwaukee, Wisconsin, United States

Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin, United States

Ascension Mercy Hospital, Oshkosh, Wisconsin, United States

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin, United States

Aurora Cancer Care-Racine, Racine, Wisconsin, United States

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin, United States

Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin, United States

Aurora Medical Center in Summit, Summit, Wisconsin, United States

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin, United States

Aspirus Regional Cancer Center, Wausau, Wisconsin, United States

Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin, United States

Aurora West Allis Medical Center, West Allis, Wisconsin, United States

Froedtert West Bend Hospital/Kraemer Cancer Center, West Bend, Wisconsin, United States

Marshfield Medical Center - Weston, Weston, Wisconsin, United States

Aspirus Cancer Care - Wisconsin Rapids, Wisconsin Rapids, Wisconsin, United States

Cross Cancer Institute, Edmonton, Alberta, Canada

London Regional Cancer Program, London, Ontario, Canada

Ottawa Hospital and Cancer Center-General Campus, Ottawa, Ontario, Canada

Chaim Sheba Medical Center, Tel Hashomer, , Israel

King Faisal Specialist Hospital and Research Centre, Riyadh, , Saudi Arabia

Contact Details

Name: Puneeth Iyengar

Affiliation: NRG Oncology

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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