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Brief Title: The Efficacy and Safety of The Fuzuloparib Combination With Bevacizumab
Official Title: The Efficacy and Safety of The Fuzuloparib Combination With Bevacizumab in Maintenance Treatment for Platinum-Sensitive Recurrent Ovarian Cancer
Study ID: NCT05819060
Brief Summary: The study will be a Prospective, Single-arm, Phase Ⅱ Clinical Study. This study intends to explore the efficacy and safety of Fuzuloparib combined with bevacizumab in the maintenance treatment of patients with platinum-sensitive ovarian cancer. The progression-free survival, OS, and safety were evaluated based on RECIST V1.1.
Detailed Description: Due to the lack of effective predictive molecular markers in the maintenance treatment phase, it is difficult to assess the effectiveness of maintenance treatment. This project plans to collect blood and urine from subjects before maintenance treatment, during relapse, and for follow-up molecular marker exploration research.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Fudan University Shanghai Cancer Cente, Shanghai, Shanghai, China
Name: Zhong Zheng, Ph.D
Affiliation: Department of Gynecologic Oncology, Fudan University Shanghai Cancer
Role: PRINCIPAL_INVESTIGATOR