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Brief Title: Propranolol Administration in Pediatric Patients With Recurrent Respiratory Papillomatosis
Official Title: Propranolol Administration in Pediatric Patients With Recurrent Respiratory Papillomatosis
Study ID: NCT01058317
Brief Summary: Juvenile onset recurrent respiratory papillomatosis (JORRP) is a rare, difficult to treat, benign tumor of the pediatric airway. Current therapy is mainly surgical, but in a significant portion of patients adjuvant therapy is required to control the disease process. Although multiple adjuvant medical therapies have been tried, success has been limited. We have seen some success in a limited amount of patients using orally administered propranolol. Our goal is to enroll a larger cohort of patients to determine the effectiveness of propranolol as an adjuvant therapy for JORRP.
Detailed Description:
Minimum Age: 1 Year
Eligible Ages: CHILD
Sex: ALL
Healthy Volunteers: No
Name: Christopher Hartnick, MD
Affiliation: Massachusetts Eye and Ear Infirmary
Role: PRINCIPAL_INVESTIGATOR