Spots Global Cancer Trial Database for Doxorubicin Hydrochloride, Cisplatin, and Paclitaxel or Carboplatin and Paclitaxel in Treating Patients With Stage III-IV or Recurrent Endometrial Cancer
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Trial Identification
Brief Title: Doxorubicin Hydrochloride, Cisplatin, and Paclitaxel or Carboplatin and Paclitaxel in Treating Patients With Stage III-IV or Recurrent Endometrial Cancer
Official Title: Randomized Phase III Trial of Doxorubicin/Cisplatin/Paclitaxel and G-CSF Versus Carboplatin/Paclitaxel in Patients With Stage III &Amp; IV or Recurrent Endometrial Cancer
Study ID: NCT00063999
Study Description
Brief Summary: This randomized phase III trial compares how well two different combination chemotherapy regimens (doxorubicin hydrochloride, cisplatin, and paclitaxel versus carboplatin and paclitaxel) work in treating patients with endometrial cancer that is stage III-IV or has come back (recurrent). Drugs used in chemotherapy such as doxorubicin hydrochloride, cisplatin, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known which combination chemotherapy regimen is more effective in treating endometrial cancer.
Detailed Description: PRIMARY OBJECTIVES: I. To determine if the combination of carboplatin and paclitaxel (TC) chemotherapy is therapeutically equivalent to the combination of doxorubicin (doxorubicin hydrochloride), cisplatin and paclitaxel (TAP) chemotherapy with regards to survival. II. To determine if estrogen/progesterone receptor status provides prognostic information in patients treated with chemotherapy. III. To assess whether combination TC chemotherapy is superior to combination TAP chemotherapy with regards to toxicity profile, specifically neurotoxicity and infection. IV. To measure differences in patient-reported neurotoxicity and quality of life (QOL) among the regimens. OUTLINE: Patients are randomized to 1 of 2 treatment arms. Patients with left ventricular ejection fraction \< 50% at randomization who are initially randomized to Arm I are immediately crossed over to Arm II. ARM I: Patients receive doxorubicin hydrochloride intravenously (IV) over approximately 15-30 minutes on day 1, cisplatin IV over 60-90 minutes on day 1, paclitaxel IV over 3 hours on day 2, and filgrastim subcutaneously (SC) on days 3-12 or pegfilgrastim SC on day 3. ARM II: Patients receive paclitaxel IV over 3 hours and carboplatin IV over 30-60 minutes on day 1. In both arms, treatment repeats every 21 days for 7 courses in the absence of disease progression or unacceptable toxicity. After completion of study treatment, patients are followed up every 3 months for 2 years, every 6 months for 3 years, and then annually thereafter.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
Clearview Cancer Institute, Huntsville, Alabama, United States
Mobile Infirmary Medical Center, Mobile, Alabama, United States
Providence Hospital, Mobile, Alabama, United States
Providence Alaska Medical Center, Anchorage, Alaska, United States
Mayo Clinic in Arizona, Scottsdale, Arizona, United States
Highlands Oncology Group PA - Fayetteville, Fayetteville, Arkansas, United States
Washington Regional Medical Center - Fayetteville, Fayetteville, Arkansas, United States
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, United States
John Muir Medical Center-Concord Campus, Concord, California, United States
City of Hope Comprehensive Cancer Center, Duarte, California, United States
Kaiser Permanente-Fremont, Fremont, California, United States
Saint Jude Medical Center, Fullerton, California, United States
Marin Cancer Care Inc, Greenbrae, California, United States
Long Beach Memorial Medical Center-Todd Cancer Institute, Long Beach, California, United States
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
Cedars Sinai Medical Center, Los Angeles, California, United States
UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California, United States
Community Hospital of Los Gatos, Los Gatos, California, United States
Doctors Medical Center, Modesto, California, United States
Memorial Medical Center, Modesto, California, United States
Kaiser Permanente-Oakland, Oakland, California, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California, United States
Stanford Cancer Institute Palo Alto, Palo Alto, California, United States
Kaiser Permanente-Redwood City, Redwood City, California, United States
Kaiser Permanente-Richmond, Richmond, California, United States
Kaiser Permanente-Roseville, Roseville, California, United States
Sutter Roseville Medical Center, Roseville, California, United States
Sutter Medical Center Sacramento, Sacramento, California, United States
University of California Davis Comprehensive Cancer Center, Sacramento, California, United States
Kaiser Permanente-South Sacramento, Sacramento, California, United States
Kaiser Permanente - Sacramento, Sacramento, California, United States
Salinas Valley Memorial, Salinas, California, United States
University of California San Diego, San Diego, California, United States
Alvarado Hospital Medical Center, San Diego, California, United States
Zuckerberg San Francisco General Hospital, San Francisco, California, United States
Kaiser Permanente-San Francisco, San Francisco, California, United States
UCSF Medical Center-Mount Zion, San Francisco, California, United States
Kaiser Permanente-Santa Teresa-San Jose, San Jose, California, United States
Kaiser Permanente San Leandro, San Leandro, California, United States
Kaiser Permanente-San Rafael, San Rafael, California, United States
Cancer Center of Santa Barbara, Santa Barbara, California, United States
Ridley-Tree Cancer Center, Santa Barbara, California, United States
Sansum Clinic Inc, Santa Barbara, California, United States
Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California, United States
Kaiser Permanente-Santa Rosa, Santa Rosa, California, United States
Ridley-Tree Cancer Center-Solvang, Solvang, California, United States
Kaiser Permanente-South San Francisco, South San Francisco, California, United States
Kaiser Permanente-Stockton, Stockton, California, United States
Olive View-University of California Los Angeles Medical Center, Sylmar, California, United States
Kaiser Permanente-Vallejo, Vallejo, California, United States
Kaiser Permanente-Walnut Creek, Walnut Creek, California, United States
John Muir Medical Center-Walnut Creek, Walnut Creek, California, United States
Colorado Gynecologic Oncology Group, Aurora, Colorado, United States
University of Colorado, Denver, Colorado, United States
Rocky Mountain Gynecologic Oncology PC, Englewood, Colorado, United States
Poudre Valley Hospital, Fort Collins, Colorado, United States
Hartford Hospital, Hartford, Connecticut, United States
Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut, United States
The Hospital of Central Connecticut, New Britain, Connecticut, United States
Yale University, New Haven, Connecticut, United States
Beebe Medical Center, Lewes, Delaware, United States
Christiana Care Health System-Christiana Hospital, Newark, Delaware, United States
TidalHealth Nanticoke / Allen Cancer Center, Seaford, Delaware, United States
Saint Francis Hospital - Wilmington, Wilmington, Delaware, United States
MedStar Washington Hospital Center, Washington, District of Columbia, United States
Morton Plant Hospital, Clearwater, Florida, United States
Broward Health Medical Center, Fort Lauderdale, Florida, United States
Florida Gynecologic Oncology, Fort Myers, Florida, United States
Saint Vincent's Medical Center, Jacksonville, Florida, United States
Mayo Clinic in Florida, Jacksonville, Florida, United States
Jupiter Medical Center, Jupiter, Florida, United States
Mercy Hospital, Miami, Florida, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida, United States
AdventHealth Orlando, Orlando, Florida, United States
Orlando Health Cancer Institute, Orlando, Florida, United States
Bayfront Outpatient Health Clinic, Saint Petersburg, Florida, United States
Sarasota Memorial Hospital, Sarasota, Florida, United States
Moffitt Cancer Center, Tampa, Florida, United States
Florida Cancer Specialists-West Palm Beach, West Palm Beach, Florida, United States
Southeastern Gynecologic Oncology LLP, Atlanta, Georgia, United States
Piedmont Hospital, Atlanta, Georgia, United States
Atlanta Regional CCOP, Atlanta, Georgia, United States
Emory Saint Joseph's Hospital, Atlanta, Georgia, United States
Northside Hospital, Atlanta, Georgia, United States
Augusta University Medical Center, Augusta, Georgia, United States
WellStar Cobb Hospital, Austell, Georgia, United States
John B Amos Cancer Center, Columbus, Georgia, United States
Dekalb Medical Center, Decatur, Georgia, United States
Northeast Georgia Medical Center-Gainesville, Gainesville, Georgia, United States
Northside Hospital - Gwinnett, Lawrenceville, Georgia, United States
Central Georgia Gynecologic Oncology, Macon, Georgia, United States
Wellstar Kennestone Hospital, Marietta, Georgia, United States
Southern Regional Medical Center, Riverdale, Georgia, United States
Harbin Clinic Medical Oncology and Clinical Research, Rome, Georgia, United States
Memorial Health University Medical Center, Savannah, Georgia, United States
Pali Momi Medical Center, 'Aiea, Hawaii, United States
Hawaii Cancer Care Inc - Waterfront Plaza, Honolulu, Hawaii, United States
Queen's Medical Center, Honolulu, Hawaii, United States
Straub Clinic and Hospital, Honolulu, Hawaii, United States
University of Hawaii Cancer Center, Honolulu, Hawaii, United States
Queen's Cancer Center - Kuakini, Honolulu, Hawaii, United States
The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii, United States
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii, United States
Pacific Cancer Institute of Maui, Wailuku, Hawaii, United States
Saint Anthony's Health, Alton, Illinois, United States
Northwest Community Hospital, Arlington Heights, Illinois, United States
Rush - Copley Medical Center, Aurora, Illinois, United States
Saint Joseph Medical Center, Bloomington, Illinois, United States
Graham Hospital Association, Canton, Illinois, United States
Memorial Hospital, Carthage, Illinois, United States
Mount Sinai Hospital Medical Center, Chicago, Illinois, United States
Northwestern University, Chicago, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
University of Illinois, Chicago, Illinois, United States
Swedish Covenant Hospital, Chicago, Illinois, United States
University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States
Decatur Memorial Hospital, Decatur, Illinois, United States
Heartland Cancer Research NCORP, Decatur, Illinois, United States
Eureka Hospital, Eureka, Illinois, United States
NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois, United States
Saint Francis Hospital, Evanston, Illinois, United States
Galesburg Cottage Hospital, Galesburg, Illinois, United States
Illinois CancerCare-Galesburg, Galesburg, Illinois, United States
Western Illinois Cancer Treatment Center, Galesburg, Illinois, United States
Ingalls Memorial Hospital, Harvey, Illinois, United States
Mason District Hospital, Havana, Illinois, United States
Hinsdale Hematology Oncology Associates Incorporated, Hinsdale, Illinois, United States
Hopedale Medical Complex - Hospital, Hopedale, Illinois, United States
Duly Health and Care Joliet, Joliet, Illinois, United States
Presence Saint Mary's Hospital, Kankakee, Illinois, United States
Kewanee Hospital, Kewanee, Illinois, United States
Mcdonough District Hospital, Macomb, Illinois, United States
Loyola University Medical Center, Maywood, Illinois, United States
Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States
Bromenn Regional Medical Center, Normal, Illinois, United States
Carle Cancer Institute Normal, Normal, Illinois, United States
Franciscan St. James Health-Olympia Fields Campus, Olympia Fields, Illinois, United States
Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois, United States
Ottawa Regional Hospital and Healthcare Center, Ottawa, Illinois, United States
Chicago Gynecologic Oncology SC, Palatine, Illinois, United States
Advocate Lutheran General Hospital, Park Ridge, Illinois, United States
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center, Pekin, Illinois, United States
Pekin Hospital, Pekin, Illinois, United States
Proctor Hospital, Peoria, Illinois, United States
Illinois CancerCare-Peoria, Peoria, Illinois, United States
Methodist Medical Center of Illinois, Peoria, Illinois, United States
OSF Saint Francis Medical Center, Peoria, Illinois, United States
Illinois Valley Hospital, Peru, Illinois, United States
Valley Radiation Oncology, Peru, Illinois, United States
Perry Memorial Hospital, Princeton, Illinois, United States
Swedish American Hospital, Rockford, Illinois, United States
OSF Saint Anthony Medical Center, Rockford, Illinois, United States
Sarah Culbertson Memorial Hospital, Rushville, Illinois, United States
Saint Margaret's Hospital, Spring Valley, Illinois, United States
Memorial Medical Center, Springfield, Illinois, United States
Carle Cancer Center, Urbana, Illinois, United States
Franciscan Saint Francis Health-Beech Grove, Beech Grove, Indiana, United States
Elkhart General Hospital, Elkhart, Indiana, United States
Fort Wayne Medical Oncology and Hematology Inc-Parkview, Fort Wayne, Indiana, United States
Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States
Saint Vincent Hospital and Health Care Center, Indianapolis, Indiana, United States
Community Howard Regional Health, Kokomo, Indiana, United States
IU Health La Porte Hospital, La Porte, Indiana, United States
Franciscan Saint Anthony Health-Michigan City, Michigan City, Indiana, United States
Saint Joseph Regional Medical Center-Mishawaka, Mishawaka, Indiana, United States
Reid Health, Richmond, Indiana, United States
Memorial Hospital of South Bend, South Bend, Indiana, United States
Michiana Hematology Oncology PC-South Bend, South Bend, Indiana, United States
South Bend Clinic, South Bend, Indiana, United States
Northern Indiana Cancer Research Consortium, South Bend, Indiana, United States
McFarland Clinic PC - Ames, Ames, Iowa, United States
University of Iowa Healthcare Cancer Services Quad Cities, Bettendorf, Iowa, United States
Saint Luke's Hospital, Cedar Rapids, Iowa, United States
Mercy Hospital, Cedar Rapids, Iowa, United States
Oncology Associates at Mercy Medical Center, Cedar Rapids, Iowa, United States
Medical Oncology and Hematology Associates-West Des Moines, Clive, Iowa, United States
Genesis Medical Center - East Campus, Davenport, Iowa, United States
Genesis Cancer Care Institute, Davenport, Iowa, United States
Mercy Capitol, Des Moines, Iowa, United States
Iowa Methodist Medical Center, Des Moines, Iowa, United States
Iowa-Wide Oncology Research Coalition NCORP, Des Moines, Iowa, United States
Medical Oncology and Hematology Associates-Des Moines, Des Moines, Iowa, United States
Medical Oncology and Hematology Associates-Laurel, Des Moines, Iowa, United States
Mercy Medical Center - Des Moines, Des Moines, Iowa, United States
Iowa Lutheran Hospital, Des Moines, Iowa, United States
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa, United States
Mercy Medical Center - North Iowa, Mason City, Iowa, United States
Siouxland Regional Cancer Center, Sioux City, Iowa, United States
Mercy Medical Center-Sioux City, Sioux City, Iowa, United States
Saint Luke's Regional Medical Center, Sioux City, Iowa, United States
Cancer Center of Kansas - Chanute, Chanute, Kansas, United States
Cancer Center of Kansas - Dodge City, Dodge City, Kansas, United States
Cancer Center of Kansas - El Dorado, El Dorado, Kansas, United States
Cancer Center of Kansas-Independence, Independence, Kansas, United States
Providence Medical Center, Kansas City, Kansas, United States
University of Kansas Cancer Center, Kansas City, Kansas, United States
Cancer Center of Kansas-Kingman, Kingman, Kansas, United States
Lawrence Memorial Hospital, Lawrence, Kansas, United States
Southwest Medical Center, Liberal, Kansas, United States
Cancer Center of Kansas - Newton, Newton, Kansas, United States
Menorah Medical Center, Overland Park, Kansas, United States
Radiation Oncology Practice Corporation Southwest, Overland Park, Kansas, United States
Cancer Center of Kansas - Parsons, Parsons, Kansas, United States
Ascension Via Christi - Pittsburg, Pittsburg, Kansas, United States
Cancer Center of Kansas - Pratt, Pratt, Kansas, United States
Cancer Center of Kansas - Salina, Salina, Kansas, United States
Advent Health - Shawnee Mission Medical Center, Shawnee Mission, Kansas, United States
Cotton O'Neil Cancer Center / Stormont Vail Health, Topeka, Kansas, United States
University of Kansas Health System Saint Francis Campus, Topeka, Kansas, United States
Cancer Center of Kansas - Wellington, Wellington, Kansas, United States
Associates In Womens Health, Wichita, Kansas, United States
Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas, United States
Ascension Via Christi Hospitals Wichita, Wichita, Kansas, United States
Cancer Center of Kansas - Wichita, Wichita, Kansas, United States
Wichita NCI Community Oncology Research Program, Wichita, Kansas, United States
Cancer Center of Kansas - Winfield, Winfield, Kansas, United States
Saint Elizabeth Medical Center South, Edgewood, Kentucky, United States
University of Kentucky/Markey Cancer Center, Lexington, Kentucky, United States
Norton Hospital Pavilion and Medical Campus, Louisville, Kentucky, United States
The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky, United States
Baton Rouge General Medical Center, Baton Rouge, Louisiana, United States
Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, United States
Woman's Hospital, Baton Rouge, Louisiana, United States
Louisiana State University Health Science Center, New Orleans, Louisiana, United States
Tulane University Health Sciences Center, New Orleans, Louisiana, United States
University Medical Center New Orleans, New Orleans, Louisiana, United States
Ochsner Medical Center Jefferson, New Orleans, Louisiana, United States
Maine Medical Center-Bramhall Campus, Portland, Maine, United States
University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland, United States
Greater Baltimore Medical Center, Baltimore, Maryland, United States
MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore, Maryland, United States
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland, United States
University of Maryland Shore Medical Center at Easton, Easton, Maryland, United States
Christiana Care - Union Hospital, Elkton, Maryland, United States
Kaiser Permanente - Largo Medical Center, Largo, Maryland, United States
Kaiser Permanente - Towson Medical Center, Lutherville, Maryland, United States
Kaiser Permanente - Shady Grove Medical Center, Rockville, Maryland, United States
TidalHealth Peninsula Regional, Salisbury, Maryland, United States
Tufts Medical Center, Boston, Massachusetts, United States
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States
Brigham and Women's Hospital, Boston, Massachusetts, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Dana Farber Community Cancer Care-Quincy, Quincy, Massachusetts, United States
Baystate Medical Center, Springfield, Massachusetts, United States
UMass Memorial Medical Center - University Campus, Worcester, Massachusetts, United States
Bixby Medical Center, Adrian, Michigan, United States
Hickman Cancer Center, Adrian, Michigan, United States
Michigan Cancer Research Consortium NCORP, Ann Arbor, Michigan, United States
Saint Joseph Mercy Hospital, Ann Arbor, Michigan, United States
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States
Bronson Battle Creek, Battle Creek, Michigan, United States
Spectrum Health Big Rapids Hospital, Big Rapids, Michigan, United States
Beaumont Hospital - Dearborn, Dearborn, Michigan, United States
Wayne State University/Karmanos Cancer Institute, Detroit, Michigan, United States
Henry Ford Hospital, Detroit, Michigan, United States
Ascension Saint John Hospital, Detroit, Michigan, United States
Green Bay Oncology - Escanaba, Escanaba, Michigan, United States
Hurley Medical Center, Flint, Michigan, United States
Genesys Regional Medical Center-West Flint Campus, Flint, Michigan, United States
Cancer Research Consortium of West Michigan NCORP, Grand Rapids, Michigan, United States
Mercy Health Saint Mary's, Grand Rapids, Michigan, United States
Spectrum Health at Butterworth Campus, Grand Rapids, Michigan, United States
Spectrum Health-Blodgett Campus, Grand Rapids, Michigan, United States
Holland Community Hospital, Holland, Michigan, United States
Green Bay Oncology - Iron Mountain, Iron Mountain, Michigan, United States
Allegiance Health, Jackson, Michigan, United States
Bronson Methodist Hospital, Kalamazoo, Michigan, United States
West Michigan Cancer Center, Kalamazoo, Michigan, United States
Kalamazoo Center for Medical Studies, Kalamazoo, Michigan, United States
Borgess Medical Center, Kalamazoo, Michigan, United States
Sparrow Hospital, Lansing, Michigan, United States
Saint Mary Mercy Hospital, Livonia, Michigan, United States
Mercy Memorial Hospital, Monroe, Michigan, United States
Toledo Clinic Cancer Centers-Monroe, Monroe, Michigan, United States
Mercy Health Partners-Hackley Campus, Muskegon, Michigan, United States
Mercy Health Mercy Campus, Muskegon, Michigan, United States
McLaren Cancer Institute-Northern Michigan, Petoskey, Michigan, United States
Saint Joseph Mercy Oakland, Pontiac, Michigan, United States
Lake Huron Medical Center, Port Huron, Michigan, United States
William Beaumont Hospital-Royal Oak, Royal Oak, Michigan, United States
Ascension Saint Mary's Hospital, Saginaw, Michigan, United States
Lakeland Medical Center Saint Joseph, Saint Joseph, Michigan, United States
Ascension Providence Hospitals - Southfield, Southfield, Michigan, United States
Munson Medical Center, Traverse City, Michigan, United States
Saint John Macomb-Oakland Hospital, Warren, Michigan, United States
Metro Health Hospital, Wyoming, Michigan, United States
Sanford Joe Lueken Cancer Center, Bemidji, Minnesota, United States
Fairview Ridges Hospital, Burnsville, Minnesota, United States
Mercy Hospital, Coon Rapids, Minnesota, United States
Essentia Health Cancer Center, Duluth, Minnesota, United States
Essentia Health Saint Mary's Medical Center, Duluth, Minnesota, United States
Miller-Dwan Hospital, Duluth, Minnesota, United States
Fairview Southdale Hospital, Edina, Minnesota, United States
Unity Hospital, Fridley, Minnesota, United States
Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States
Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States
University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota, United States
North Memorial Medical Health Center, Robbinsdale, Minnesota, United States
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Metro Minnesota Community Oncology Research Consortium, Saint Louis Park, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, United States
United Hospital, Saint Paul, Minnesota, United States
Saint Francis Regional Medical Center, Shakopee, Minnesota, United States
Ridgeview Medical Center, Waconia, Minnesota, United States
Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States
Saint Dominic-Jackson Memorial Hospital, Jackson, Mississippi, United States
University of Mississippi Medical Center, Jackson, Mississippi, United States
Keesler Medical Center, Keesler Air Force Base, Mississippi, United States
Singing River Hospital, Pascagoula, Mississippi, United States
Southeast Missouri Hospital, Cape Girardeau, Missouri, United States
Saint Francis Medical Center, Cape Girardeau, Missouri, United States
University of Missouri - Ellis Fischel, Columbia, Missouri, United States
Centerpoint Medical Center LLC, Independence, Missouri, United States
Freeman Health System, Joplin, Missouri, United States
Truman Medical Centers, Kansas City, Missouri, United States
Saint Luke's Hospital of Kansas City, Kansas City, Missouri, United States
Radiation Oncology Practice Corporation South, Kansas City, Missouri, United States
Saint Joseph Health Center, Kansas City, Missouri, United States
North Kansas City Hospital, Kansas City, Missouri, United States
Research Medical Center, Kansas City, Missouri, United States
Radiation Oncology Practice Corporation - North, Kansas City, Missouri, United States
Liberty Radiation Oncology Center, Liberty, Missouri, United States
Heartland Regional Medical Center, Saint Joseph, Missouri, United States
SSM Health Saint Louis University Hospital, Saint Louis, Missouri, United States
Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Saint Mary's Hospital, Saint Louis, Missouri, United States
Missouri Baptist Medical Center, Saint Louis, Missouri, United States
Center for Cancer Care and Research, Saint Louis, Missouri, United States
Mercy Hospital Saint Louis, Saint Louis, Missouri, United States
Saint Louis-Cape Girardeau CCOP, Saint Louis, Missouri, United States
Cancer Research for the Ozarks NCORP, Springfield, Missouri, United States
Mercy Hospital Springfield, Springfield, Missouri, United States
CoxHealth South Hospital, Springfield, Missouri, United States
Billings Clinic Cancer Center, Billings, Montana, United States
Northern Rockies Radiation Oncology Center, Billings, Montana, United States
Saint Vincent Healthcare, Billings, Montana, United States
Montana Cancer Consortium NCORP, Billings, Montana, United States
Saint Vincent Frontier Cancer Center, Billings, Montana, United States
Deaconess Medical Center, Billings, Montana, United States
Bozeman Deaconess Hospital, Bozeman, Montana, United States
Internal Medicine of Bozeman, Bozeman, Montana, United States
Saint James Community Hospital and Cancer Treatment Center, Butte, Montana, United States
Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana, United States
Berdeaux, Donald MD (UIA Investigator), Great Falls, Montana, United States
Great Falls Clinic, Great Falls, Montana, United States
Northern Montana Hospital, Havre, Montana, United States
Saint Peter's Community Hospital, Helena, Montana, United States
Glacier Oncology PLLC, Kalispell, Montana, United States
Kalispell Medical Oncology, Kalispell, Montana, United States
Kalispell Regional Medical Center, Kalispell, Montana, United States
Eastern Montana Cancer Center, Miles City, Montana, United States
Montana Cancer Specialists, Missoula, Montana, United States
Saint Patrick Hospital - Community Hospital, Missoula, Montana, United States
Community Medical Hospital, Missoula, Montana, United States
Guardian Oncology and Center for Wellness, Missoula, Montana, United States
CHI Health Good Samaritan, Kearney, Nebraska, United States
Bryan LGH Medical Center West, Lincoln, Nebraska, United States
Bryan LGH Medical Center East, Lincoln, Nebraska, United States
Nebraska Cancer Research Center, Lincoln, Nebraska, United States
Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States
Nebraska Methodist Hospital, Omaha, Nebraska, United States
Alegent Health Immanuel Medical Center, Omaha, Nebraska, United States
Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States
Creighton University Medical Center, Omaha, Nebraska, United States
University of Nebraska Medical Center, Omaha, Nebraska, United States
University Medical Center of Southern Nevada, Las Vegas, Nevada, United States
Nevada Cancer Research Foundation NCORP, Las Vegas, Nevada, United States
Center of Hope at Renown Medical Center, Reno, Nevada, United States
Renown Regional Medical Center, Reno, Nevada, United States
Women's Cancer Center at Washoe, Reno, Nevada, United States
Saint Mary's Regional Medical Center, Reno, Nevada, United States
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States
Cooper Hospital University Medical Center, Camden, New Jersey, United States
Hunterdon Medical Center, Flemington, New Jersey, United States
Saint Barnabas Medical Center, Livingston, New Jersey, United States
Mountainside Hospital, Montclair, New Jersey, United States
Morristown Medical Center, Morristown, New Jersey, United States
Virtua Memorial, Mount Holly, New Jersey, United States
Inspira Medical Center Mullica Hill, Mullica Hill, New Jersey, United States
Jersey Shore Medical Center, Neptune, New Jersey, United States
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States
Rutgers New Jersey Medical School, Newark, New Jersey, United States
AtlantiCare Regional Medical Center -Main Campus, Pomona, New Jersey, United States
Riverview Medical Center/Booker Cancer Center, Red Bank, New Jersey, United States
Sparta Cancer Treatment Center, Sparta, New Jersey, United States
Overlook Hospital, Summit, New Jersey, United States
Inspira Medical Center Vineland, Vineland, New Jersey, United States
Virtua Voorhees, Voorhees, New Jersey, United States
University of New Mexico Cancer Center, Albuquerque, New Mexico, United States
Southwest Gynecologic Oncology Associates Inc, Albuquerque, New Mexico, United States
New York Oncology Hematology PC - Albany Medical Center, Albany, New York, United States
Women's Cancer Care Associates LLC, Albany, New York, United States
New York Oncology Hematology PC - Amsterdam, Amsterdam, New York, United States
Island Gynecologic Oncology, Brightwaters, New York, United States
Montefiore Medical Center-Einstein Campus, Bronx, New York, United States
Montefiore Medical Center-Wakefield Campus, Bronx, New York, United States
Montefiore Medical Center - Moses Campus, Bronx, New York, United States
State University of New York Downstate Medical Center, Brooklyn, New York, United States
Roswell Park Cancer Institute, Buffalo, New York, United States
New York Oncology Hematology PC - Clifton Park, Clifton Park, New York, United States
New York Oncology Hematology PC-Hudson, Hudson, New York, United States
Northwell Health NCORP, Lake Success, New York, United States
North Shore University Hospital, Manhasset, New York, United States
Long Island Jewish Medical Center, New Hyde Park, New York, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York, United States
Mount Sinai Hospital, New York, New York, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
South Nassau Communities, Oceanside, New York, United States
Stony Brook University Medical Center, Stony Brook, New York, United States
Good Samaritan Hospital Medical Center, West Islip, New York, United States
Randolph Hospital, Asheboro, North Carolina, United States
Hope Women's Cancer Centers-Asheville, Asheville, North Carolina, United States
Cone Health Cancer Center at Alamance Regional, Burlington, North Carolina, United States
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina, United States
Novant Health Presbyterian Medical Center, Charlotte, North Carolina, United States
Duke University Medical Center, Durham, North Carolina, United States
Moorehead Memorial Hospital, Eden, North Carolina, United States
Wayne Memorial Hospital, Goldsboro, North Carolina, United States
Wayne Radiation Oncology, Goldsboro, North Carolina, United States
Cone Health Cancer Center, Greensboro, North Carolina, United States
Gynecologic Oncology Network, Greenville, North Carolina, United States
Vidant Medical Center, Greenville, North Carolina, United States
Vidant Oncology-Kinston, Kinston, North Carolina, United States
FirstHealth of the Carolinas-Moore Regional Hospital, Pinehurst, North Carolina, United States
Annie Penn Memorial Hospital, Reidsville, North Carolina, United States
Wilson Medical Center, Wilson, North Carolina, United States
Novant Health Oncology Specialists, Winston-Salem, North Carolina, United States
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States
Mid Dakota Clinic, Bismarck, North Dakota, United States
Saint Alexius Medical Center, Bismarck, North Dakota, United States
Sanford Bismarck Medical Center, Bismarck, North Dakota, United States
Sanford Broadway Medical Center, Fargo, North Dakota, United States
Summa Health System - Akron Campus, Akron, Ohio, United States
Cleveland Clinic Akron General, Akron, Ohio, United States
Saint Elizabeth Boardman Hospital, Boardman, Ohio, United States
Toledo Clinic Cancer Centers-Bowling Green, Bowling Green, Ohio, United States
Cleveland Clinic Mercy Hospital, Canton, Ohio, United States
Aultman Health Foundation, Canton, Ohio, United States
University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio, United States
Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio, United States
Case Western Reserve University, Cleveland, Ohio, United States
MetroHealth Medical Center, Cleveland, Ohio, United States
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio, United States
Cleveland Clinic Foundation, Cleveland, Ohio, United States
North Coast Cancer Care-Clyde, Clyde, Ohio, United States
Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
Riverside Methodist Hospital, Columbus, Ohio, United States
Mount Carmel Health Center West, Columbus, Ohio, United States
Grandview Hospital, Dayton, Ohio, United States
Good Samaritan Hospital - Dayton, Dayton, Ohio, United States
Miami Valley Hospital, Dayton, Ohio, United States
Miami Valley Hospital North, Dayton, Ohio, United States
Dayton Veterans Affairs Medical Center, Dayton, Ohio, United States
Dayton NCI Community Oncology Research Program, Dayton, Ohio, United States
Hematology Oncology Center Incorporated, Elyria, Ohio, United States
Blanchard Valley Hospital, Findlay, Ohio, United States
Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio, United States
Fremont Memorial Hospital, Fremont, Ohio, United States
Kettering Medical Center, Kettering, Ohio, United States
Saint Rita's Medical Center, Lima, Ohio, United States
Lima Memorial Hospital, Lima, Ohio, United States
Saint Luke's Hospital, Maumee, Ohio, United States
Toledo Clinic Cancer Centers-Maumee, Maumee, Ohio, United States
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center, Maumee, Ohio, United States
Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio, United States
UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio, United States
Saint Charles Hospital, Oregon, Ohio, United States
Toledo Clinic Cancer Centers-Oregon, Oregon, Ohio, United States
UH Seidman Cancer Center at Salem Regional Medical Center, Salem, Ohio, United States
Firelands Regional Medical Center, Sandusky, Ohio, United States
North Coast Cancer Care, Sandusky, Ohio, United States
ProMedica Flower Hospital, Sylvania, Ohio, United States
Mercy Hospital of Tiffin, Tiffin, Ohio, United States
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio, United States
Saint Vincent Mercy Medical Center, Toledo, Ohio, United States
University of Toledo, Toledo, Ohio, United States
Toledo Community Hospital Oncology Program CCOP, Toledo, Ohio, United States
Mercy Health - Saint Anne Hospital, Toledo, Ohio, United States
Toledo Clinic Cancer Centers-Toledo, Toledo, Ohio, United States
Upper Valley Medical Center, Troy, Ohio, United States
Saint Joseph Warren Hospital, Warren, Ohio, United States
Fulton County Health Center, Wauseon, Ohio, United States
Clinton Memorial Hospital, Wilmington, Ohio, United States
Cancer Treatment Center, Wooster, Ohio, United States
Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio, United States
Greene Memorial Hospital, Xenia, Ohio, United States
Saint Elizabeth Youngstown Hospital, Youngstown, Ohio, United States
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma, United States
Three Rivers Community Hospital, Grants Pass, Oregon, United States
Asante Health System, Medford, Oregon, United States
Providence Medford Medical Center, Medford, Oregon, United States
Rogue Valley Medical Center, Medford, Oregon, United States
Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon, United States
Compass Oncology Rose Quarter, Portland, Oregon, United States
Kaiser Permanente Northwest, Portland, Oregon, United States
Oregon Health and Science University, Portland, Oregon, United States
Jefferson Abington Hospital, Abington, Pennsylvania, United States
Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania, United States
Saint Luke's University Hospital-Bethlehem Campus, Bethlehem, Pennsylvania, United States
Bryn Mawr Hospital, Bryn Mawr, Pennsylvania, United States
Marion Community Hospital, Carbondale, Pennsylvania, United States
Mercy Fitzgerald Hospital, Darby, Pennsylvania, United States
Oncology Hematology Associates of Northern Pennsylvania, DuBois, Pennsylvania, United States
Pocono Medical Center, East Stroudsburg, Pennsylvania, United States
Ephrata Cancer Center, Ephrata, Pennsylvania, United States
Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, United States
Riddle Memorial Hospital, Media, Pennsylvania, United States
Paoli Memorial Hospital, Paoli, Pennsylvania, United States
Drexel University School of Medicine, Philadelphia, Pennsylvania, United States
University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania, United States
Pennsylvania Hospital, Philadelphia, Pennsylvania, United States
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
Jefferson Torresdale Hospital, Philadelphia, Pennsylvania, United States
Temple University Hospital, Philadelphia, Pennsylvania, United States
Einstein Medical Center Philadelphia, Philadelphia, Pennsylvania, United States
UPMC-Magee Womens Hospital, Pittsburgh, Pennsylvania, United States
West Penn Hospital, Pittsburgh, Pennsylvania, United States
Guthrie Medical Group PC-Robert Packer Hospital, Sayre, Pennsylvania, United States
Mercy Hospital, Scranton, Pennsylvania, United States
Hematology and Oncology Associates of North East Pennsylvania, Scranton, Pennsylvania, United States
Moses Taylor Hospital, Scranton, Pennsylvania, United States
Scranton Hematology Oncology, Scranton, Pennsylvania, United States
Associates In Hematology Oncology PC-Upland, Upland, Pennsylvania, United States
Reading Hospital, West Reading, Pennsylvania, United States
Lankenau Medical Center, Wynnewood, Pennsylvania, United States
Main Line Health NCORP, Wynnewood, Pennsylvania, United States
Women and Infants Hospital, Providence, Rhode Island, United States
Medical University of South Carolina, Charleston, South Carolina, United States
Prisma Health Richland Hospital, Columbia, South Carolina, United States
University of South Carolina School of Medicine, Columbia, South Carolina, United States
South Carolina Oncology Associates PA, Columbia, South Carolina, United States
Black Hills Obstetrics and Gynecology, Rapid City, South Dakota, United States
Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota, United States
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota, United States
Chattanooga's Program in Women's Oncology, Chattanooga, Tennessee, United States
East Tennessee State University, Johnson City, Tennessee, United States
Southeast Gynecologic Oncology Associates, Knoxville, Tennessee, United States
East Tennessee Baptist Hospital-Mercy Health Partners, Knoxville, Tennessee, United States
Knoxville Gynecologic Cancer Specialists PC, Knoxville, Tennessee, United States
Baptist Memorial Hospital and Cancer Center-Memphis, Memphis, Tennessee, United States
University of Tennessee Health Science Center, Memphis, Tennessee, United States
Meharry Medical College, Nashville, Tennessee, United States
Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States
The Don and Sybil Harrington Cancer Center, Amarillo, Texas, United States
Parkland Memorial Hospital, Dallas, Texas, United States
Clements University Hospital, Dallas, Texas, United States
UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas, United States
Brooke Army Medical Center, Fort Sam Houston, Texas, United States
University of Texas Medical Branch, Galveston, Texas, United States
Houston Methodist Hospital, Houston, Texas, United States
M D Anderson Cancer Center, Houston, Texas, United States
Texas Tech University Health Sciences Center-Lubbock, Lubbock, Texas, United States
Scott and White Memorial Hospital, Temple, Texas, United States
American Fork Hospital / Huntsman Intermountain Cancer Center, American Fork, Utah, United States
Sandra L Maxwell Cancer Center, Cedar City, Utah, United States
Logan Regional Hospital, Logan, Utah, United States
Cottonwood Hospital Medical Center, Murray, Utah, United States
Intermountain Medical Center, Murray, Utah, United States
McKay-Dee Hospital Center, Ogden, Utah, United States
Utah Valley Regional Medical Center, Provo, Utah, United States
Dixie Medical Center Regional Cancer Center, Saint George, Utah, United States
Intermountain Health Care, Salt Lake City, Utah, United States
Utah Cancer Specialists-Salt Lake City, Salt Lake City, Utah, United States
Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah, United States
LDS Hospital, Salt Lake City, Utah, United States
University of Vermont Medical Center, Burlington, Vermont, United States
Northern Virginia Pelvic Surgery Associates, Annandale, Virginia, United States
University of Virginia Cancer Center, Charlottesville, Virginia, United States
Danville Regional Medical Center, Danville, Virginia, United States
Kaiser Permanente - Fair Oaks Medical Center, Fairfax, Virginia, United States
Southside Community Hospital, Farmville, Virginia, United States
Fredericksburg Oncology Inc, Fredericksburg, Virginia, United States
Peninsula Cancer Institute-Gloucester, Gloucester, Virginia, United States
Virginia Oncology Associates-Hampton, Hampton, Virginia, United States
Rappahannock General Hospital, Kilmarnock, Virginia, United States
Peninsula Cancer Institute-Newport News, Newport News, Virginia, United States
Bon Secours Mary Immaculate Hospital, Newport News, Virginia, United States
Virginia Oncology Associates - Lake Wright, Norfolk, Virginia, United States
Bon Secours Saint Mary's Hospital, Richmond, Virginia, United States
Richmond Radiation Oncology Center, Richmond, Virginia, United States
Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia, United States
Oncology and Hematology Associates of Southwest Virginia, Roanoke, Virginia, United States
Carilion Clinic Gynecological Oncology, Roanoke, Virginia, United States
VCU Community Memorial Health Center, South Hill, Virginia, United States
Peninsula Cancer Institute-Williamsburg, Williamsburg, Virginia, United States
Fred Hutchinson Cancer Research Center, Seattle, Washington, United States
University of Washington Medical Center - Montlake, Seattle, Washington, United States
MultiCare Tacoma General Hospital, Tacoma, Washington, United States
Northwest Medical Specialties PLLC, Tacoma, Washington, United States
PeaceHealth Southwest Medical Center, Vancouver, Washington, United States
HSHS Sacred Heart Hospital, Eau Claire, Wisconsin, United States
Marshfield Clinic Cancer Center at Sacred Heart, Eau Claire, Wisconsin, United States
Saint Agnes Hospital/Agnesian Cancer Center, Fond Du Lac, Wisconsin, United States
Green Bay Oncology at Saint Vincent Hospital, Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin, United States
Green Bay Oncology Limited at Saint Mary's Hospital, Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin, United States
Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States
University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States
Holy Family Memorial Hospital, Manitowoc, Wisconsin, United States
Bay Area Medical Center, Marinette, Wisconsin, United States
Marshfield Medical Center-Marshfield, Marshfield, Wisconsin, United States
Marshfield Medical Center, Marshfield, Wisconsin, United States
Ascension Columbia Saint Mary's Hospital Ozaukee, Mequon, Wisconsin, United States
Ascension Columbia Saint Mary's Hospital - Milwaukee, Milwaukee, Wisconsin, United States
Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin, United States
Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin, United States
ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Oconto Falls, Oconto Falls, Wisconsin, United States
Ascension All Saints Hospital, Racine, Wisconsin, United States
Ascension Saint Mary's Hospital, Rhinelander, Wisconsin, United States
Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin, United States
Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin, United States
Vince Lombardi Cancer Clinic - Slinger, Slinger, Wisconsin, United States
Ascension Saint Michael's Hospital, Stevens Point, Wisconsin, United States
Green Bay Oncology - Sturgeon Bay, Sturgeon Bay, Wisconsin, United States
ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin, United States
Marshfield Clinic-Wausau Center, Wausau, Wisconsin, United States
Aurora West Allis Medical Center, West Allis, Wisconsin, United States
Marshfield Medical Center - Weston, Weston, Wisconsin, United States
Marshfield Clinic - Wisconsin Rapids Center, Wisconsin Rapids, Wisconsin, United States
Welch Cancer Center, Sheridan, Wyoming, United States
McGill University Health Centre at Royal Victoria Hospital, Montreal, Quebec, Canada
Montreal General Hospital, Montreal, Quebec, Canada
Saint Mary's Hospital, Montreal, Quebec, Canada
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ), Quebec City, Quebec, Canada
Tohoku University School of Medicine, Sendai, Aoba-ku, Japan
Kure National Hospital, Kure, Hiroshima, Japan
Hokkaido University Hospital, Sapporo, Hokkaido, Japan
Iwate Medical University Hospital, Shiwa-gun, Iwate, Japan
Kagoshima City Hospital, Kagoshima City, Kagoshima, Japan
Jikei University Aoto Hospital, Katsushika-ku, Tokyo, Japan
Keio University, Shinjuku-ku, Tokyo, Japan
Hiroshima University Hospital, Hiroshima City, , Japan
National Hospital Organization-Kobe Medical Center, Kobe, , Japan
Shikoku Cancer Center, Matsuyama, , Japan
National Kyushu Cancer Center, Minami-ku, , Japan
Jikei University School of Medicine, Minato-ku, Tokyo, , Japan
Saitama Medical University International Medical Center, Saitama, , Japan
National Cancer Center Hospital, Tokyo, , Japan
Tottori University, Tottori, , Japan
Contact Details
Name: David S Miller
Affiliation: NRG Oncology
Role: PRINCIPAL_INVESTIGATOR
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