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Spots Global Cancer Trial Database for Molecular Profiling Protocol (SCRI-CA-001)

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Molecular Profiling Protocol (SCRI-CA-001)

Official Title: A Pilot Study Utilizing Molecular Profiling of Patients' Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers

Study ID: NCT00530192

Study Description

Brief Summary: This is an open-label, multicenter pilot study in patients with advanced solid tumors. The primary objective of this study is to compare progression-free survival using a treatment regimen selected by molecular profiling with progression-free survival for the most recent regimen the patient has progressed on. To be eligible, patients must have received at least two lines of prior chemotherapeutic, hormonal or biological regimens for advanced disease, have measurable or evaluable, refractory disease and have clear documentation of the time between treatment start and documented progression on the last treatment prior to study entry. Eligible patients must undergo or have available a tumor biopsy for molecular profiling within 2 months of IHC/FISH and/or DNA microarray analysis.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Oncology Specialties, Huntsville, Alabama, United States

TGen Clinical Research Services, Scottsdale, Arizona, United States

Mayo Clinic, Scottsdale, Arizona, United States

Tower Oncology, Beverly Hills, California, United States

Louis Warschaw Prostate Cancer Center at Cedars Sinai Medical Center, Los Angeles, California, United States

Central Indiana Cancer Center, Indianapolis, Indiana, United States

Cancer Center of the Carolinas, Greenville, South Carolina, United States

South Texas Oncology Hematology, San Antonio, Texas, United States

Tyler Cancer Center, Tyler, Texas, United States

Contact Details

Name: Daniel D Von Hoff, MD

Affiliation: TGen Clinical Research Services at Scottsdale Healthcare

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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