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Spots Global Cancer Trial Database for IMA401 TCER® in Recurrent and/or Refractory Solid Tumors

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Trial Identification

Brief Title: IMA401 TCER® in Recurrent and/or Refractory Solid Tumors

Official Title: A Phase Ia/Ib First-In-Human Clinical Trial to Evaluate the Safety, Tolerability and Initial Anti-tumor Activity of IMA401, a Bispecific T Cell Engaging Receptor Molecule (TCER®), in Patients With Recurrent and/or Refractory Solid Tumors.

Study ID: NCT05359445

Study Description

Brief Summary: Primary objective: * To determine the maximum tolerated dose and/or recommended dose for extension for IMA401 Secondary objectives: * To characterize the safety and tolerability of IMA401 * To evaluate initial anti-tumor activity of IMA401 * To describe the pharmacokinetics of IMA401

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Universitaetsklinikum Freiburg, Zentralklinikum, Klinik fuer Innere Medizin I, Freiburg, Baden-Wurttemberg, Germany

Universitaetsklinikum Heidelberg AöR, Nationales Zentrum fuer Tumorkrankheiten, Heidelberg, Baden-Wurttemberg, Germany

Universitaetsklinikum Tuebingen AöR, Comprehensive Cancer Center Tuebingen, Tuebingen, Baden-Wurttemberg, Germany

Universitaetsklinikum Ulm AöR, ECTU-Early clinical Trials Unit Universitaetsklinikum Ulm Comprehensive Cancer Center Ulm_CCCU, Ulm, Baden-Wurttemberg, Germany

Universitaetsklinikum Erlangen AöR, Interdisciplinary Clinical Trial Unit with ECTU, Erlangen, Bavaria, Germany

Klinikum rechts der Isar der TU Muenchen AöR, Klinik und Poliklinik fuer Innere Medizin III, Munich, Bavaria, Germany

Klinikum Nuernberg, Klinik fuer Innere Medizin 5, Abteilung Onkologie/Haematologie, Nuremberg, Bavaria, Germany

Universitaetsklinikum Regensburg AöR, Klinik fuer Innere Medizin 3, Regensburg, Bavaria, Germany

Universitaetsklinikum Wuerzburg AöR, Interdisziplinaeres Studienzentrum mit ECTU, Wuerzburg, Bavaria, Germany

Medizinische Hochschule Hannover, Klinik fuer Haematologie, Haemostaseologie, Onkologie und Stammzelltransplantation, Hanover, Lower Saxony, Germany

Universitätsklinikum Bonn AöR, Medizinische Klinik IIII, Bonn, North Rhine-Westphalia, Germany

Marien Hospital Duesseldorf GmbH, Klinik fuer Onkologie/Haematologie und Palliativmedizin, Duesseldorf, North Rhine-Westphalia, Germany

Universitaetsklinikum Essen AöR, Innere Klinik (Tumorforschung) Westdeutsches Tumorzentrum Essen, Essen, North Rhine-Westphalia, Germany

Universitaetsklinikum Muenster AöR, Medizinische Klinik A, Muenster, North Rhine-Westphalia, Germany

Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, III. Medizinische Klinik, Mainz, Rhineland-Palatinate, Germany

Klinikum Chemnitz gGmbH, Klinik für Innere Medizin III, Chemnitz, Saxony, Germany

Universitaetsklinikum C. - G. - Carus Dresden, Technische Universitaet Dresden AöR, NCT/UCC Early Clinical Trial Unit, Dresden, Saxony, Germany

Universitaet Leipzig, Universitaeres Krebszentrum Leipzig (UCCL), Leipzig, Saxony, Germany

Universitaetsklinikum Schleswig- Holstein, Campus Kiel, Medizinische Klinik II Haematologie und Onkologie, Karl-Lennert Tumorzentrum, Kiel, Schleswig- Holstein, Germany

Charité Universitaetsmedizin Berlin KöR, Klinik fuer Haematologie und Onkologie, Berlin, , Germany

Contact Details

Name: Immatics Biotechnologies GmbH

Affiliation: Immatics Biotechnologies GmbH

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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