Spots Global Cancer Trial Database for Study of CP-675,206 in Refractory Melanoma
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Trial Identification
Brief Title: Study of CP-675,206 in Refractory Melanoma
Official Title: A Phase 2, Open Label, Single Arm Study To Evaluate The Efficacy, Safety, Tolerability And Pharmacokinetics Of CP-675,206 In Patients With Advanced Refractory And/Or Relapsed Melanoma
Study ID: NCT00254579
Conditions
Interventions
Study Description
Brief Summary: CP-675,206 is a fully human monoclonal antibody (mAb). It binds to the CTLA4 molecule, which is expressed on the surface of activated T lymphocytes. CP-675,206 is thought to stimulate patients' immune systems to attack their tumors. CP-675,206 is not expected to have a direct effect on tumor cells. CP-675,206 been shown to induce durable tumor responses in patients with metastatic melanoma in Phase 1 and Phase 2 clinical studies.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Scottsdale, Arizona, United States
Research Site, Bentonville, Arkansas, United States
Research Site, Fayetteville, Arkansas, United States
Research Site, Little Rock, Arkansas, United States
Research Site, Los Angeles, California, United States
Research Site, Los Angeles, California, United States
Research Site, Aurora, Colorado, United States
Research Site, Stamford, Connecticut, United States
Research Site, Ocoee, Florida, United States
Research Site, Orlando, Florida, United States
Research Site, Orlando, Florida, United States
Research Site, Chicago, Illinois, United States
Research Site, Indianapolis, Indiana, United States
Research Site, Indianapolis, Indiana, United States
Research Site, Indianapolis, Indiana, United States
Research Site, Louisville, Kentucky, United States
Research Site, Baltimore, Maryland, United States
Research Site, Boston, Massachusetts, United States
Research Site, Ann Arbor, Michigan, United States
Research Site, Buffalo, New York, United States
Research Site, New York, New York, United States
Research Site, Chapel Hill, North Carolina, United States
Research Site, Durham, North Carolina, United States
Pfizer Investigational Site, Columbus, Ohio, United States
Research Site, Columbus, Ohio, United States
Research Site, Bethlehem, Pennsylvania, United States
Research Site, Pittsburgh, Pennsylvania, United States
Research Site, Nashville, Tennessee, United States
Research Site, Nashville, Tennessee, United States
Research Site, Salt Lake City, Utah, United States
Research Site, Federal Way, Washington, United States
Research Site, Lakewood, Washington, United States
Research Site, Seattle, Washington, United States
Research Site, Seattle, Washington, United States
Research Site, Tacoma, Washington, United States
Research Site, Madison, Wisconsin, United States
Research Site, Ciudad de Buenos Aires, Buenos Aires, Argentina
Research Site, Waratah, New South Wales, Australia
Research Site, Westmead, New South Wales, Australia
Research Site, Woolloongabba, Queensland, Australia
Research Site, East Melbourne, Victoria, Australia
Research Site, Nedlands, Western Australia, Australia
Research Site, Hamilton, Ontario, Canada
Research Site, Lille, Cedex, France
Research Site, Paris Cedex 13, , France
Research Site, Villejuif, , France
Research Site, Berlin, , Germany
Research Site, Frankfurt, , Germany
Research Site, Kiel, , Germany
Research Site, Tuebingen, , Germany
Research Site, Meldola, FC, , Italy
Research Site, Milano, , Italy
Research Site, Milano, , Italy
Research Site, Milano, , Italy
Research Site, Pamplona, Navarra, Spain
Research Site, Barcelona, , Spain
Research Site, Madrid, , Spain
Research Site, Zaragoza, , Spain
Research Site, Truro, Cornwall, United Kingdom
Research Site, Northwood, Middlesex, United Kingdom
Research Site, Sutton, Surrey, United Kingdom
Research Site, Newcastle upon Tyne, Tyne and Wear, United Kingdom
Research Site, London, , United Kingdom
Research Site, Manchester, , United Kingdom
Research Site, Newcastle Upon Tyne, , United Kingdom
Contact Details
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