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Brief Title: Semi-automated Segmentation Methods of SSTR PET for Dosimetry Prediction
Official Title: Semi-automated Segmentation Methods of SSTR PET for Dosimetry Prediction in Refractory Meningiomas Treated by SSTR-targeted Peptide Receptor Radionuclide Therapy
Study ID: NCT05537675
Brief Summary: Tumor dosimetry with somatostatin receptor-targeted peptide receptor radionuclide therapy (SSTR-targeted PRRT) by 177Lutetium-DOTATATE might contribute to improve follow-up and treatment response of refractory meningiomas. This study aims to evaluate Standard Uptake Value mean (SUVmean) as a tumoral absorbed dose predictive predictive factor and propose semi-automated segmentation method to determine metabolic tumor volume with pretherapeutic 68-Gallium-DOTATOC PET.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Nuclear medicine Department CHRU de NANCY, Vandoeuvre les Nancy cedex, , France
Name: Anne-Sophie HUE, MSc
Affiliation: CHRU Nancy
Role: STUDY_DIRECTOR