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Brief Title: A Study Evaluating The Safety And Pharmacokinetics Of Escalating Doses Of RO7297089 In Patients With Relapsed Or Refractory Multiple Myeloma
Official Title: An Open-Label, Multicenter, Phase I Trial Evaluating The Safety And Pharmacokinetics Of Escalating Doses Of RO7297089 In Patients With Relapsed Or Refractory Multiple Myeloma
Study ID: NCT04434469
Brief Summary: This is a first-in-human Phase I, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, and pharmacokinetics of RO7297089 and make a preliminary assessment of anti-tumor activity in patients with R/R MM for whom no established therapy for MM is appropriate and available or who are intolerant to those established therapies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Concord Repatriation General Hospital, Concord, New South Wales, Australia
LIVERPOOL HOSPITAL; HAEMATOLOGY; Ingham Institute for Medical Research, Liverpool, New South Wales, Australia
Royal Adelaide Hospital; Haematology Clinical Trials, Adelaide, South Australia, Australia
St. Vincent's Hospital Melbourne, Fitzroy, South Australia, Australia
Peter Mac Callum Cancer Center, East Melbourne, Victoria, Australia
UZ Gent, Gent, , Belgium
UZ Leuven, Leuven, , Belgium
Rigshospitalet, København Ø, , Denmark
Vejle Sygehus; Onkologisk Afdeling, Vejle, , Denmark
Oslo Universitetssykehus HF; Ullevål sykehus, Oslo, , Norway
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_DIRECTOR