Spots Global Cancer Trial Database for Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid Tumors
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Trial Identification
Brief Title: Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid Tumors
Official Title: Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid Tumors
Study ID: NCT02688881
Conditions
Interventions
Study Description
Brief Summary: This study is a single arm, pilot study of sirolimus in patient with Phosphatidylinositide-3-kinase (PIK3CA) mutation, PIK3CA amplification , PIK3CA-AKT pathway aberration Refractory solid tumor and/or specific sensitivity to mTOR inhibitors by Avatar scan that has progressed following standard therapy or that has not responded to standard therapy or for which there is no standard therapy. sirolimus 1mg will be administered orally daily. To investigate the efficacy and safety of sirolimus in patient with Refractory solid tumor.
Detailed Description:
Keywords
Eligibility
Minimum Age: 19 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Samsung Medical Center, Seoul, , Korea, Republic of
Contact Details
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