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Spots Global Cancer Trial Database for Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

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Trial Identification

Brief Title: Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

Official Title: Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

Study ID: NCT05237258

Study Description

Brief Summary: This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute myeloid leukemia (AML).

Detailed Description: Patients with newly diagnosed AML confront a sudden and life-threatening diagnosis, requiring an immediate disruption of their life and an urgent hospitalization to begin therapy. During their hospitalization for chemotherapy, patients with AML often experience difficult physical symptoms that negatively impact their quality of life and physical function. Patients with AML also experience significant psychological distress as they combat the abrupt onset of illness, uncertainty regarding their prognosis, physical and social isolation during hospitalization, and complete loss of independence. The abrupt onset of these symptoms can be distressing to both the patient and their family and friends (also called "caregivers"). Research has shown that early involvement of a team of clinicians specializing in lessening (or "palliating") these physical and emotional symptoms and helping patients and their caregivers cope with AML improves their quality of life and experience with their illness. This team is called "specialty palliative care" and consists of physicians and advanced practice providers who work closely and collaboratively with the oncology team to care for patients and caregivers. Research has also shown that training oncology clinicians to incorporate palliative care skills into their practice, called "primary palliative care," is an alternative strategy to having specialty palliative care clinicians care for patients with leukemia. The purpose of this study is to determine whether specialty palliative care or primary palliative care is the best way to improve the quality of life and experience of patients with AML and their caregivers. This study will randomly assign hospitals to deliver either specialty palliative care or primary palliative care for patients with AML. Participants in this study will receive either specialty or primary palliative care during their hospital stays based upon which strategy their hospital has been assigned to. Participants assigned to specialty palliative care will be care for by both oncology and palliative care clinicians during their hospital stays for AML. Participants assigned to primary palliative care will be cared for by oncology clinicians who have been trained in palliative care during their hospital stays for AML.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

University of Alabama - Birmingham, Birmingham, Alabama, United States

Stanford University, Stanford, California, United States

University of Colorado Denver I Anschutz Medical Campus, Denver, Colorado, United States

University of Miami, Miami, Florida, United States

Moffitt Cancer Center, Tampa, Florida, United States

Emory University, Atlanta, Georgia, United States

Northwestern University, Evanston, Illinois, United States

Indiana University, Bloomington, Indiana, United States

Johns Hopkins University, Baltimore, Maryland, United States

Massachusetts General Hospital, Boston, Massachusetts, United States

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Mayo Clinic, Rochester, Minnesota, United States

University of Rochester, Rochester, New York, United States

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

Duke University, Durham, North Carolina, United States

Ohio State University, Columbus, Ohio, United States

Oregon Health & Science University, Portland, Oregon, United States

University of Pennsylvania, Philadelphia, Pennsylvania, United States

Fred Hutchinson Cancer Center, Seattle, Washington, United States

University of Wisconsin, Madison, Wisconsin, United States

Contact Details

Name: Areej El-Jawahri, MD

Affiliation: Massachusetts General Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Jennifer Temel, MD

Affiliation: Massachusetts General Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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