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Brief Title: Study to Evaluate the Efficacy and Safety of Loncastuximab Tesirine Versus Idelalisib in Participants With Relapsed or Refractory Follicular Lymphoma
Official Title: A Phase 2 Randomized Study of Loncastuximab Tesirine Versus Idelalisib in Patients With Relapsed or Refractory Follicular Lymphoma (LOTIS-6)
Study ID: NCT04699461
Brief Summary: This study aims to evaluate the efficacy of single agent loncastuximab tesirine compared to idelalisib in participants with relapsed or refractory follicular lymphoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
Summit Medical Group - Florham Park Campus, Florham Park, New Jersey, United States
Summit Medical Group, Florham Park, New Jersey, United States
Hollings Cancer Center, Charleston, South Carolina, United States
Universitair Ziekenhuis Gent, Gent, , Belgium
Centre Hospitalier Universitaire Universite Catholique de Louvain, Yvoir, , Belgium
Centre Hospitalier de Dunkerque, Dunkerque, , France
Centre Hospitalier de La Rochelle, La Rochelle, , France
Centre de Lutte Contre le Cancer - Centre Henri-Becquerel, Rouen, , France
Hôpital Bretonneau, Tours Cedex 9, , France
Semmelweis Egyetem, Budapest, , Hungary
Országos Onkológiai Intézet, Budapest, , Hungary
Pécsi Tudományegyetem Klinikai Központ, Pécs, , Hungary
Soroka Medical Center, Be'er Sheva, , Israel
Carmel Medical Center, Haifa, , Israel
Rabin Medical Center - Beilinson Hospital, Petah tikva, , Israel
The Chaim Sheba Medical Center, Tel Aviv, , Israel
Tel Aviv Sourasky Medical Center, Tel Aviv, , Israel
Azienda Ospedaliero - Universitaria Careggi, Firenze, , Italy
Szpitale Pomorskie Spółka Z Ograniczoną Odpowiedzialnością, Gdynia, , Poland
Pratia Onkologia Katowice, Katowice, , Poland
Pratia Poznań, Skorzewo, , Poland
Institut Català d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet), L'Hospitalet De Llobregat, , Spain
Hospital Universitari Arnau de Vilanova, Lleida, , Spain
Hospital Universitario Ramón y Cajal, Madrid, , Spain
Hospital General Universitario Gregorio Marañón, Madrid, , Spain
Hospital Universitario Fundación Jiménez Díaz, Madrid, , Spain
Hospital Universitario La Paz, Madrid, , Spain
Hospital Universitario Quirónsalud Madrid, Pozuelo De Alarcón, , Spain
Hospital Universitario Virgen del Rocío, Sevilla, , Spain
Inselspital Universitätsspital Bern, Bern, , Switzerland
NHS Greater Glasgow and Clyde, Glasgow, , United Kingdom
Account University College London Hospitals NHS Foundation Trust, London, , United Kingdom