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Brief Title: Study of Lenalidomide to Evaluate Safety and Efficacy in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
Official Title: A Phase 2, Multi-Center, Randomized, Double-Blinded, Parallel Group Study of the Safety and Efficacy of Different Lenalidomide (REVLIMID®) Dose Regimens in Subjects With Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia
Study ID: NCT00963105
Brief Summary: The purpose of this study is to determine the safety and effectiveness of different dose regimens of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia (CLL).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
UCSD Moores Cancer Center, La Jolla, California, United States
Desert Hematology Oncology Medical Group, Inc., Rancho Mirage, California, United States
Stanford University School of Medicine, Stanford, California, United States
Cancer Center of Central Connecticut, Southington, Connecticut, United States
Cancer and Blood Disease Center, Lecanto, Florida, United States
Northwestern University Medical Center Division of Hematology Oncology, Chicago, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
Indiana University Cancer Center, Indianapolis, Indiana, United States
Karmanos Cancer Institute, Detroit, Michigan, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Roswell Park Cancer Institute, Buffalo, New York, United States
Long Island Jewish Medical Center CLL Research and Treatment Program, New Hyde Park, New York, United States
Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States
Gabrail Cancer Center Research, Canton, Ohio, United States
Cleveland Clinic Foundation, Cleveland, Ohio, United States
Drexel University, College of Medicine, Clinical Research Group, Philadelphia, Pennsylvania, United States
Cross Cancer Institute, Edmonton, Alberta, Canada
Juravinski Cancer Centre, Hamilton, Ontario, Canada
CHU Sud, Amiens, , France
Hopital Avicenne, Bobigny Cedex, , France
CHU Grenoble, Grenoble Cedex 09, , France
Clinique Victor Hugo, Le Mans, , France
Institut Paoli Calmettes, Marseille Cedex 9, , France
CHU Montpellier - Hôpital Saint Eloi, Montpellier Cedex 5, , France
Hopital Emile Muller, Mulhouse, , France
Hopital Pitie Salpetriere, Paris, , France
CH Perpignan - Hopital Saint-Jean, Perpignan, , France
CHRU - Hopital du Haut Leveque, Pessac, , France
Centre Hospitalier Lyon Sud, Pierre Bénite, , France
Hopital Robert Debre, REIMS cedex, , France
CHU Rennes Hematology, Rennes cedex, , France
CHRU Hopital Brabois, Vandoeuvre les Nancy, , France
Charite -Universitätsmedizin Berlin, Berlin, , Germany
Universitatsklinikum Essen, Essen, , Germany
Ernst-Moritz-Arndt-Universität Greifswald, Greifswald, , Germany
Universitatsklinikum Schleswig Holstein, Kiel, , Germany
Klinikum der Universitat zu Koln, Köln, , Germany
University of Ulm Abteilung Innere Medizin III, Ulm, , Germany
Azienda Ospedaliera Universitaria San Martino, Genova, , Italy
Ematologia ed Immunologia, Azienda Ospedaliera "Vito Fazzi" di Lecce, Lecce, , Italy
I.R.C.C.S. Ospedale San Raffaele, Milano, , Italy
Istituto Europeo di Oncologia - IEO, Milano, , Italy
Universita degli Studi di Padova, Padova, , Italy
Universita' Degli Studi Di Perugia, Perugia, , Italy
Hospital Clinic Provincial de Barcelona, Barcelona, , Spain
Hospital Universitari Germans Trias i Pujol, Barcelona, , Spain
Karolinska Universitetssjukhuset, Stockholm, , Sweden
St James's Institute of Oncology, Leeds, , United Kingdom
St.Bartholomew's Hospital, London, , United Kingdom
King's College Hospital, London, , United Kingdom
The Royal Marsden Hospital, London, , United Kingdom
Christie Hospital NHS Foundation Trust, Manchester, , United Kingdom
Name: Jeffery Jones, M.D., MPH
Affiliation: Celgene Corporation
Role: STUDY_DIRECTOR