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Brief Title: Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies
Official Title: A Phase 1, Open-Label, Multicentre, Non-Randomized Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of AZD4573, a Potent and Selective CDK9 Inhibitor, in Subjects With Relapsed or Refractory Haematological Malignancies
Study ID: NCT03263637
Brief Summary: The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary antitumor activity of AZD4573 in subjects with relapsed or refractory haematological malignancies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Aachen, , Germany
Research Site, Bonn, , Germany
Research Site, Göttingen, , Germany
Research Site, Heidelberg, , Germany
Research Site, Ulm, , Germany
Research Site, Amsterdam, , Netherlands
Research Site, Nieuwegein, , Netherlands
Research Site, Cardiff, , United Kingdom
Research Site, Manchester, , United Kingdom
Research Site, Plymouth, , United Kingdom
Research Site, Southampton, , United Kingdom
Research Site, Sutton, , United Kingdom