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Brief Title: INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma
Official Title: A Randomized Open-Label Phase 1/2 Study of INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Participants With Relapsed or Refractory Multiple Myeloma
Study ID: NCT03837509
Brief Summary: The purpose of this study is to evaluate the safety and antitumor activity of INCB001158 in combination with daratumumab SC, compared with daratumumab SC alone, in participants with relapsed or refractory multiple myeloma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Southern Cancer Center, Daphne, Alabama, United States
Arizona Oncology Associates (Wilmot), Tucson, Arizona, United States
Rocky Mountain Cancer Centers, Denver, Colorado, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
Comprehensive Cancer Centers of Nevada - Twain, Las Vegas, Nevada, United States
New York Oncology Hematology, Albany, New York, United States
Lineberger Comprehensive Cancer Center At University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States
Oncology Hematology Care, Inc, Cincinnati, Ohio, United States
Texas Oncology-Austin Midtown, Austin, Texas, United States
Texas Oncology - Fort Worth South Henderson, Fort Worth, Texas, United States
Texas Oncology San Antonio, San Antonio, Texas, United States
Texas Oncology - Tyler, Tyler, Texas, United States
University of Virginia, Charlottesville, Virginia, United States
Virginia Cancer Specialists-Fairfax, Fairfax, Virginia, United States
Charite - Universit�Tsmedizin Berlin, Berlin, , Germany
University of Heidelberg, Heidelberg, , Germany
Universitatsmedizin Der Johannes Gutenberg-Universitat Mainz Iii, Mainz, , Germany
Universitatsklinikum Munster, Munster, , Germany
Hospital General Universitari Vall D Hebron, Barcelona, , Spain
Hospital Clinic I Provincial, Barcelona, , Spain
Ico Institut Catala D Oncologia, Barcelona, , Spain
Hospital Universitario Ramon Y Cajal, Madrid, , Spain
Fundacion Jimenez Diaz University Hospital, Madrid, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Clinica Universidad de Navarra (Cun), Pamplona, , Spain
Hospital Clinico Universitario de Salamanca, Salamanca, , Spain
Hospital Universitario Marques de Valdecilla, Santander, , Spain
Hospital Universitario Doctor Peset, Valencia, , Spain
Hospital Universitario Y Politcnico de La Fe, Valencia, , Spain
Name: Sven Gogov, MD
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR