Spots Global Cancer Trial Database for Study of TQB2450 Injection in Subjects With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma
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Trial Identification
Brief Title: Study of TQB2450 Injection in Subjects With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma
Official Title: A Phase II, Multicenter, Open, Single-arm Study of TQB2450 Injection (PD-L1 Antibody) in Subjects With Relapsed or Refractory Primary Mediastinal B-cell Lymphoma (rrPMBCL)
Study ID: NCT04002622
Interventions
Study Description
Brief Summary: TQB2450 is a humanized monoclonal antibody targeting programmed death ligand-1 (PD-L1), which prevents PD-L1 from binding to PD-1 and B7.1 receptors on T cell surface, restores T cell activity, thus enhancing immune response and has potential to treat various types of tumors.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Peking University First Hospital, Beijing, Beijing, China
Fifth Medical Center of the Chinese People's Liberation Army General Hospital, Beijing, Beijing, China
Peking Union Medical College Hospital, Beijing, Beijing, China
Peking University Third Hospital, Beijin, Beijing, China
Peking Hospital, Beijin, Beijing, China
Union Medical College Hospital Affiliated to Fujian Medical University, Fuzhou, Fujian, China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
Cancer Hospital Affiliated to Harbin Medical University, Ha'erbin, Heilongjiang, China
Henan Cancer Hospital, Zhengzhou, Henan, China
Henan People's Hospital, Zhengzhou, Henan, China
Hunan Canser Hospital, Changsha, Hunan, China
First Hospital of Jilin University, Changchun, Jilin, China
First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China
Qilu Hospital of Shandong University, Jinan, Shandong, China
Affiliated Hospital of Qingdao University, Qingdao, Shandong, China
Shanghai Tongji Hospital, Shanghai, Shanghai, China
Shanghai Tumor Hospital, Shanghai, Shanghai, China
Zhejiang Tumor Hospital, Hangzhou, Zhejiang, China
Contact Details
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