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Brief Title: Study of Panobinostat in Combination With Sorafenib in Kidney, Soft Tissue or Lung Cancers
Official Title: A Phase I Safety and Tolerability Study of LBH589 in Combination With Sorafenib in Patients With Advanced Renal Cell Carcinoma, Soft Tissue Sarcoma, and Non-small Cell Lung Carcinoma (NSCLC) of Non-squamous Histologies.
Study ID: NCT01005797
Brief Summary: The purpose of this study is to determine if a new investigational drug called Panobinostat is safe, tolerable and to obtain an initial assessment of efficacy, when given in combination with Sorafenib for the treatment of certain types of lung cancer, kidney cancer and soft tissue sarcoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Medical University of South Carolina Hollings Cancer Center, Charleston, South Carolina, United States
Name: Harry Drabkin, MD
Affiliation: Medical University of South Carolina
Role: PRINCIPAL_INVESTIGATOR